Mahmoud Salama
A5047370443- Reproductive Biology and Fertility
- Reproductive Health and Technologies
- Ovarian function and disorders
- Renal and related cancers
- Cancer Risks and Factors
- Assisted Reproductive Technology and Twin Pregnancy
- Cardiac, Anesthesia and Surgical Outcomes
- Pluripotent Stem Cells Research
- Tissue Engineering and Regenerative Medicine
- Nerve Injury and Rehabilitation
- BRCA gene mutations in cancer
- Peripheral Nerve Disorders
- Ovarian cancer diagnosis and treatment
- Nerve injury and regeneration
- Cancer Research and Treatments
- Colorectal Cancer Surgical Treatments
- Surgical site infection prevention
- Acute Lymphoblastic Leukemia research
- Hernia repair and management
- Orthopedic Surgery and Rehabilitation
- 3D Printing in Biomedical Research
- Birth, Development, and Health
- Demographic Trends and Gender Preferences
- Pelvic and Acetabular Injuries
- Ultrasound and Hyperthermia Applications
Barts Health NHS Trust
2024
Queen Elizabeth Hospital Birmingham
2024
Michigan State University
2021-2024
Manchester Royal Infirmary
2024
Royal London Hospital
2024
Bradford Royal Infirmary
2024
University Hospitals Birmingham NHS Foundation Trust
2024
Royal Derby Hospital
2024
National Health Service
2024
Alexandria University
2021-2024
Fertility preservation (FP) is an important quality of life issue for cancer survivors reproductive age. Despite the existence broad international guidelines, delivery oncofertility care, particularly amongst paediatric, adolescent and young adult patients, remains a challenge healthcare professionals (HCPs). The care variable uptake utilization FP low. Available guidelines fall short in providing adequate detail on how models (MOC) allow real-world application by HCPs.
Importance Young women with breast cancer who have germline pathogenic variants in BRCA1 or BRCA2 face unique challenges regarding fertility. Previous studies demonstrating the feasibility and safety of pregnancy survivors included limited data BRCA carriers. Objective To investigate cumulative incidence disease-free survival young are Design, Setting, Participants International, multicenter, hospital-based, retrospective cohort study conducted at 78 participating centers worldwide. The...
Abstract Background The incidence of cancer diagnosed during pregnancy is increasing. Data relating to investigation and management, as well maternal foetal outcomes lacking in a United Kingdom (UK) population. Methods In this retrospective study we report data from 119 patients with 14 centres the UK across five-year period (2016-2020). Results Median age at diagnosis was 33 years, breast, skin haematological most common primary sites. majority cases were new diagnoses (109 patients,...
Oncofertility focuses on providing fertility and endocrine-sparing options to patients who undergo life-preserving but gonadotoxic cancer treatment. The resources needed meet patient demand often are fragmented along disciplinary lines. We quantify assets gaps in oncofertility care a global scale.Survey-based questionnaires were provided 191 members of the Consortium Global Partners Network, National Institutes Health-funded organization. Responses analyzed measure trends regional subtleties...
Despite international evidence about fertility preservation (FP), several barriers still prevent the implementation of equitable FP practice. Currently, oncofertility competencies do not exist. The aim this study was to develop an competency framework that defines key components care, develops a model for prioritizing service development, and roles health care professionals (HCPs) play.A quantitative modified Delphi methodology used conduct two rounds electronic survey, querying synthesizing...
Purpose In the accompanying article, “Survey of Fertility Preservation Options Available to Patients With Cancer Around Globe,” we showed that specific fertility preservation services may not be offered at various sites around world because cultural and legal barriers. We assessed global regional experiences as well status third-party reproduction adoption serve a comprehensive international data set resource for groups wish begin oncofertility interventions. Methods provide on legalities...
Phosphatidylserine is the phospholipid component which plays a key role in cell cycle signaling, specifically regards to necrosis and apoptosis. When affected by some negative factors, phosphatidylserine no longer restricted intracellular side of membrane can be translocated extracellular surface cell. Cryopreservation induce translocation response hypoxia, increasing Ca2+, osmotic disruption cellular membranes, generation reactive oxygen species lipid peroxidation. As such aim this study...
Oncofertility is an emerging discipline which aims to preserve fertility of young cancer patients. As preservation services have become increasingly available patients in many countries around the globe, it crucial establish a foundation collaborative reporting continuously monitor and assess oncofertility practices. This survey study investigates current global landscape official national registries, vital tool allows for surveillance field.
It is not uncommon for a severe traumatic brachial plexus injury to involve all 5 roots, resulting in flail upper limb. In such cases, surgical reconstruction often palliative, providing only rudimentary function. Nerve transfers are the mainstay of reconstructive strategies due predominance root avulsions. Consistent results obtained restoration shoulder stability and elbow flexion, whereas restoring useful hand function remains challenge. The transfer contralateral C-7 (cC-7) commonly used...
The state of limited resource settings that Coronavirus (COVID-19) pandemic has created globally should be taken seriously into account especially in healthcare sector. In oncofertility, patients receive their fertility preservation treatments urgently even before initiation anticancer therapy. Therefore, it is very crucial to learn more about oncofertility practice such as developing countries suffer often from shortage services provided young with cancer. As an extrapolation during the...
Little is known about oncofertility practice in developing countries that usually suffer from a shortage of health services, especially those related to cancer care.
Oncofertility practice continues to grow in developing countries despite the lack of health care services, especially those related cancer care. The purpose this study is further explore oncofertility these and identify opportunities for field-wide coalescence.
Oncofertility practice continues to grow in developing countries despite the lack of health care services, especially those related cancer care. The purpose this study is further explore oncofertility these and identify opportunities for field-wide coalescence.