A5009098657- Breast Cancer Treatment Studies
- Breast Lesions and Carcinomas
- Breast Implant and Reconstruction
- Radiomics and Machine Learning in Medical Imaging
- Cancer Risks and Factors
- MRI in cancer diagnosis
- Estrogen and related hormone effects
- Advanced Radiotherapy Techniques
- Reproductive Biology and Fertility
- HER2/EGFR in Cancer Research
- Cancer Treatment and Pharmacology
- Reconstructive Surgery and Microvascular Techniques
- Cancer Diagnosis and Treatment
- Medical Imaging Techniques and Applications
- BRCA gene mutations in cancer
- Cancer Genomics and Diagnostics
- Radiopharmaceutical Chemistry and Applications
- Advanced MRI Techniques and Applications
- Brain Metastases and Treatment
- Radiation Dose and Imaging
- Advanced X-ray and CT Imaging
- Cancer Cells and Metastasis
- Advanced Breast Cancer Therapies
- Coronary Interventions and Diagnostics
- Metastasis and carcinoma case studies
University of Ulsan
1999-2025
Asan Medical Center
2009-2025
Ulsan College
1999-2025
Seoul Medical Center
2024
Seoul Veterans Hospital
2024
University of Yamanashi
2023
University of British Columbia
2023
National Cancer Center
2015-2017
Samsung Medical Center
2011-2017
Korea Institute of Radiological and Medical Sciences
2015
To determine the updated long-term outcomes of Addition Ovarian Suppression to Tamoxifen in Young Women With Hormone-Sensitive Breast Cancer Who Remain Premenopausal or Regain Vaginal Bleeding After Chemotherapy (ASTRRA) trial.This study is a post-trial follow-up ASTRRA trial, involving 1,483 premenopausal women younger than 45 years treated with definitive surgery after completing adjuvant neoadjuvant chemotherapy for estrogen receptor-positive breast cancer. Patients were randomly assigned...
Importance Young women with breast cancer who have germline pathogenic variants in BRCA1 or BRCA2 face unique challenges regarding fertility. Previous studies demonstrating the feasibility and safety of pregnancy survivors included limited data BRCA carriers. Objective To investigate cumulative incidence disease-free survival young are Design, Setting, Participants International, multicenter, hospital-based, retrospective cohort study conducted at 78 participating centers worldwide. The...
PURPOSE To investigate the clinical behavior of breast cancer in young BRCA carriers according to specific gene ( BRCA1 v BRCA2 ) and association timing genetic testing (before at diagnosis) with prognosis. METHODS This was an international, multicenter, hospital-based, retrospective cohort study that included 4,752 patients harboring germline pathogenic/likely pathogenic variants (PVs) or , who were diagnosed stage I-III invasive 40 years younger between January 2000 December 2020 78...
We investigated the safety and performance of Da Vinci SP single-port robot (SP robot) in nipple-sparing mastectomy (NSM) with immediate reconstruction. Medical records 60 women aged ≥ 19 years who had undergone robot-assisted unilateral or bilateral NSM reconstruction between October 2020 August 2021 were retrospectively analyzed. Stage I (31, 47.1%) was most common pathological tumor-node-metastasis stage, followed by stages II (22, 33.3%), 0 (7, 10.6%), III (4, 6.0%). The median total...
This study analyzed the pathological complete response (pCR) rates, long-term outcomes, and biological features of human epidermal growth factor receptor 2 (HER2)-zero, HER2-low, HER2-positive breast cancer patients undergoing neoadjuvant treatment. single-center included 1,667 who underwent chemotherapy from 2008 to 2014. Patients were categorized by HER2 status, their clinicopathological characteristics, responses, recurrence-free survival (RFS) rates analyzed. with HER2-low tumors more...
This study aimed to evaluate the clinical status of radiation therapy (RT), including RT utilization (RTU) rate and infrastructure in Korea 2020 2021. Patient data for individuals undergoing 2021 were sourced from Health Insurance Review Assessment Service. Through these data, we assessed following aspects: total number patients who received 2021, RTU with cancer, by cancer diagnosis, treated age, region, hypofractionated breast specific modality. In 90,351 97,840 patients, respectively,...
The Avoid Axillary Sentinel Lymph Node Biopsy After Neoadjuvant Chemotherapy (ASLAN) trial aims to demonstrate the oncologic safety of omitting axillary surgery in patients with excellent response after neoadjuvant chemotherapy (NACT) for early human epidermal growth factor 2 (HER2)-positive (+)/triple-negative breast cancer (TNBC) who have undergone breast-conserving (BCS) and adjuvant radiotherapy. ASLAN will provide crucial information that could change procedure highly selected undergoing NACT.
In this study, the authors compared conventional and robot-assisted mastectomy breast reconstruction. To authors' knowledge, study is first to report results of reconstruction provide a comparison patient-reported outcomes.
To determine how pulmonary paragonimiasis may be confused with lung cancer, we retrospectively analysed the clinical and radiological characteristics of 47 patients (27 males, median age 55 years; interquartile range 49-61) serologically or histopathologically confirmed seen between October 2004 December 2009.Respiratory symptoms were present in 29 (62%) patients; remaining 18 (38%) asymptomatic. Chest radiography (CXR) revealed intrapulmonary parenchymal lesions (n = 35, 75%) more...
(Abstracted from JAMA 2024;331(1):49–59 Individuals who are diagnosed with breast cancer at a young age often carriers of pathogenic variant in the BRCA1 or BRCA2 genes, and many women this situation interested preserving future fertility, if possible. Reproductive counseling can be complex due to risk passing on variant, as well implications their own mutation impact ovarian reserve, fertility potential, other factors.
Nonmass lesions (NMLs) on breast ultrasound lack clear definition and encompass a broad range of benign malignant entities. Given anticipated inclusion NMLs in the BI-RADS 6th edition, thorough understanding these will be critical for optimal management.
OBJECTIVES: Clinicians might be misled in interpreting an elevated CA19-9 when differentiating pancreaticobiliary cancer from benign clinical conditions such as acute cholangitis or cholestasis, because these conditions, the concentration of may also elevated. The aims our study were to calculate new individual cutoff values for according situations using a receiver operating characteristic (ROC) curve and define strategy cancer. METHODS: One hundred sixty patients with pancreatic diseases...
This study aimed to analyze the waiting time for initial treatment after breast cancer diagnosis and determine factors influencing delay in South Korea.This nationwide retrospective cohort was conducted using Health Insurance Review Assessment data. The participants were classified according regions where their biopsy performed (Seoul-Seoul, Metro-Metro, Other-Other, Metro-Seoul, Other-Seoul). Waiting analyzed regional subgroup, year of diagnosis, type treatment. Multivariable logistic...
Abstract Background Imaging-guided or physiology-guided percutaneous coronary intervention (PCI) improved clinical outcomes in complex artery disease. However, it is not known to what extent routine functional testing after imaging PCI affect among high-risk patients. Objectives To assess impact of test standard care alone intravascular ultrasound (IVUS) fractional flow reserve(FFR) guided PCI. Methods Of the 1706 randomized patients with anatomical features enrolled POST-PCI (Pragmatic...
One of major threatening search and destroy MRSA is rising mupirocin resistance. In a 2,200-bed tertiary care hospital, only 38-bed neonatal intensive unit (NICU) was under active surveillance decolonization colonizers for last 10 years. Mupirocin resistances isolates from NICU clinical Staphylococcus aureus the institute were compared.
Abstract Background: Oncofertility counseling in BRCA carriers has unique challenges due to a possible negative impact of germline pathogenic/likely pathogenic variants (PVs) on reproductive potential and the indication undergo risk-reducing bilateral salpingo-oophorectomy. While previous studies demonstrated safety pregnancy women with prior breast cancer (BC) history, limited evidence exists specifically. We report results largest study date investigating likelihood after BC, disease...
Abstract Background Neoadjuvant chemotherapy (NACT) for breast cancer (BC) is downstaging inoperable tumors into operable and de-escalating breast/axillary surgery. According to advanced NACT, dual human epidermal growth factor-2 (HER2) blockage in HER2-positive BC, carboplatin, immunotherapy triple-negative (TNBC) revealed pathologic complete response (ypCR) rates of up 68% 80%, the indications NACT have expanded early BC expected ypCR rate has increased. Therefore, it may be reasonable...
Abstract Background and Aims Cutaneous manifestations are frequently found in end-stage kidney disease (ESKD) disturbing quality of life patients under maintenance hemodialysis. Even dialysis visit the hospital, they do not receive active dermatologic care. The aim this study is to assess cutaneous hemodialysis investigate changes before after treatment by dermatologists. Method A 12-weeks, prospective was conducted with two centers Patients one center received intervention another...
546 Background: Invasive Lobular Carcinoma (ILC), a unique breast cancer subtype, exhibits distinct clinical and pathological features. Multigene assays, notably the Oncotype DX (ODX) test, provide personalized prognostic insights in cancer. However, research gap exists for clinical-pathological characteristics affecting multigene assay risk scores ILC. This study aims to address this gap, investigating factors specific ILC, from those invasive ductal carcinoma (IDC), contributing refined...