Seonghun Park

ORCID: 0000-0003-3209-5617
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About
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Research Areas
  • Osteoarthritis Treatment and Mechanisms
  • Orthopaedic implants and arthroplasty
  • Lower Extremity Biomechanics and Pathologies
  • Total Knee Arthroplasty Outcomes
  • Vibration Control and Rheological Fluids
  • Fatigue and fracture mechanics
  • Urological Disorders and Treatments
  • Inflammatory Bowel Disease
  • Urologic and reproductive health conditions
  • Orthopedic Infections and Treatments
  • Spine and Intervertebral Disc Pathology
  • Heat Transfer and Optimization
  • Advanced materials and composites
  • Advanced Radiotherapy Techniques
  • Vehicle Dynamics and Control Systems
  • Knee injuries and reconstruction techniques
  • Engineering Applied Research
  • Sperm and Testicular Function
  • Wave and Wind Energy Systems
  • Hydraulic and Pneumatic Systems
  • Endodontics and Root Canal Treatments
  • Seismic Performance and Analysis
  • Dental Radiography and Imaging
  • Gastric Cancer Management and Outcomes
  • Bone Metabolism and Diseases

Icahn School of Medicine at Mount Sinai
2025

Asan Medical Center
2010-2024

University of Ulsan
2010-2024

Ulsan College
2015-2024

Yonsei University
2023-2024

Colorado State University Pueblo
2024

Samsung Medical Center
2008-2023

Pusan National University
2013-2022

Pusan National University Yangsan Hospital
2010-2018

Sungkyunkwan University
2008-2016

Peroxisome proliferator-activated receptors (PPARs), members of the nuclear hormone receptor superfamily transcription factors, are key regulators in various pathophysiological processes related to energy metabolism including lipid, carbohydrate metabolism, and inflammation. At present, little information is on effect age calorie restriction (CR) PPARs. In present study, we investigated how CR (60% ad libitum intake) modulate PPARs kidneys obtained from Fischer 344 rats, ages 13 25 months....

10.1093/gerona/59.10.b997 article EN The Journals of Gerontology Series A 2004-10-01

It has been well established that articular cartilage is compositionally and mechanically inhomogeneous through its depth. To what extent this structural inhomogeneity a prerequisite for appropriate function integrity not understood. The first hypothesis to be tested in study was the depth-dependent of acts maximize interstitial fluid load support at surface, provide efficient frictional wear properties. second produces more homogeneous state elastic stress matrix than would achieved with...

10.1115/1.1610018 article EN Journal of Biomechanical Engineering 2003-10-01

Abstract The aim of this two-center randomized controlled trial was to assess the outcomes and relative factors associated with pulpotomies performed using a premixed injectable calcium silicate cement, as compared mineral trioxide aggregate in mature permanent premolar molar teeth reversible pulpitis. Included were randomly divided into two groups according pulpotomy material (ProRoot MTA [PMTA] group, Endocem Premixed [EPM] group). After pulp exposure, superficial either removed depth 2 mm...

10.1038/s41598-024-52818-6 article EN cc-by Scientific Reports 2024-02-06

<title>Abstract</title> Squalene-based adjuvants like MF59, and its research alternative AddaVax, induce transient muscle injury, but their mechanisms downstream of injury remain unclear. We show that an AddaVax-adjuvanted quadrivalent inactivated influenza virus vaccine (QIV) intramuscular injection triggers regeneration-like immune processes increases CX3CR1+Ly6C+ macrophages in the inguinal lymph nodes by day 4 post-injection. This leads to a Th2 skewed response with higher levels...

10.21203/rs.3.rs-5760877/v1 preprint EN cc-by Research Square (Research Square) 2025-01-28

PURPOSE: To evaluate the clinical effectiveness of a polyurethane-covered, retrievable, self-expandable metallic stent and hook catheter in treatment esophageal strictures. MATERIALS AND METHODS: Stents were constructed 0.4-mm stainless steel wire cylindric zig-zag configuration six to nine bends. Four eight stents connected tandem by dipping polyurethane solution. A nylon loop was hooked inside each bend proximal portion strung with thread. Under fluoroscopic guidance, 22 placed 16 patients...

10.1148/radiology.203.3.9169699 article EN Radiology 1997-06-01

Due to the prevalence of osteoarthritis (OA) and damage articular cartilage, coupled with poor intrinsic healing capacity this avascular connective tissue, there is a great demand for an cartilage substitute. As bearing material diarthrodial joints, has remarkable functional properties that have been difficult reproduce in tissue‐engineered constructs. We previously demonstrated by using tissue engineering approach incorporates mechanical loading into long‐term culture environment, one can...

10.1177/0006355x2004041003004023 article EN Biorheology 2004-05-01

Very limited information is currently available on the constitutive modeling of tensile response articular cartilage and its dynamic modulus at various loading frequencies. The objectives this study were to (1) formulate experimentally validate a model for intrinsic viscoelasticity in tension, (2) confirm hypothesis that energy dissipation tension less than compression frequencies, (3) test unconfined dependent upon modulus. Experiment 1: Immature bovine samples tested stress relaxation...

10.1115/1.2206201 article EN Journal of Biomechanical Engineering 2006-01-04

10.1007/s12555-010-0512-1 article EN International Journal of Control Automation and Systems 2010-10-01

10.1007/s12541-010-0024-1 article EN International Journal of Precision Engineering and Manufacturing 2010-04-01

Atomic force microscopy (AFM) techniques have been increasingly used for investigating the mechanical properties of articular cartilage. According to previous studies reporting microscale Young's modulus under AFM indentation tests, Hertz contact model has employed with a sharp conical tip indenter. However, non-linear behaviour cartilage could not be resolved by standardized analysis using small and atomic microscope tips. Therefore, objective this study was evaluate more accurately through...

10.1243/09544119jeim516 article EN Proceedings of the Institution of Mechanical Engineers Part H Journal of Engineering in Medicine 2009-02-03

Purpose: To investigate the causes of varicocele recurrence and assess use embolization subinguinal varicocelectomy in its treatment patients with angiography varicocelectomy.Materials Methods: The present study involved 15 recurrent varicoceles.The mean patient age was 21.2 years (range: 12-42 years).Preoperative performed 11 patients.Embolization used patent internal spermatic veins (ISVs).Patients without ISVs or preoperative underwent magnification-assisted which included testicular...

10.3349/ymj.2012.53.4.723 article EN cc-by-nc Yonsei Medical Journal 2012-01-01

To evaluate the impact of temporary internal ureteral stents on surgical outcomes dismembered pyeloplasty in children.The medical records 70 children (76 renal units) who underwent for ureteropelvic junction (UPJ) obstruction at Asan Medical Center between January 2005 and December 2010 were retrospectively reviewed. We classified units into stented group (22 nonstented (54 units). Fifty-four patients male their mean age was 2.2±3.8 years old. The follow-up period 29.6±16.8 months.Sixty-four...

10.4111/kju.2012.53.8.564 article EN Korean journal of urology 2012-01-01

The tribological performance of total hip arthroplasty has an important influence on its success rate. This study examined the concentration-dependent role hyaluronic acid (HA) and phospholipid (dipalmitoylphosphatidylcholine, DPPC) in boundary lubricating ability retrieved cobalt–chromium femoral heads. microscale frictional coefficients (μ) were measured by atomic force microscopy using a rectangular silicon cantilever integrated with sharp tips. In case HA lubricant, decreased...

10.1116/1.4886255 article EN cc-by Biointerphases 2014-07-01

Anogential distance (AGD) and the 2:4 digit length ratio appear to provide a reliable guide fetal androgen exposure. We intended investigate current status of penile size relationship between AGD or according birth weight in Korean newborn infants. Between May 2013 February 2014, among total 78 male infants, 55 infants were prospectively included this study. Newborn with gestational age 38 42 weeks weight>2.5 kg assigned NW group (n=24) those age<38 weight<2.5 LW (n=31). Penile other...

10.4111/kju.2015.56.3.248 article EN Korean journal of urology 2015-01-01
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