- Cancer and Skin Lesions
- Nonmelanoma Skin Cancer Studies
- Oral Health Pathology and Treatment
- Immunotherapy and Immune Responses
- Cutaneous Melanoma Detection and Management
- Nail Diseases and Treatments
- Medical Imaging and Pathology Studies
- Chemokine receptors and signaling
- Autoimmune and Inflammatory Disorders Research
- Hedgehog Signaling Pathway Studies
- Forest ecology and management
- Multiple Myeloma Research and Treatments
- Cancer Cells and Metastasis
- Tattoo and Body Piercing Complications
- Peroxisome Proliferator-Activated Receptors
- Peripheral Neuropathies and Disorders
- Cutaneous lymphoproliferative disorders research
- Bone and Joint Diseases
- Intestinal and Peritoneal Adhesions
- Forensic Entomology and Diptera Studies
- Soft tissue tumor case studies
- Inflammatory Myopathies and Dermatomyositis
- Insect behavior and control techniques
- Genetic factors in colorectal cancer
- Myeloproliferative Neoplasms: Diagnosis and Treatment
Instituto de Investigación Biosanitaria de Granada
2002-2022
Hospital Universitario Virgen de las Nieves
2008-2021
Complejo Hospitalario Universitario de Granada
2020
Universidad de Sevilla
1990-1998
Consejo Superior de Investigaciones Científicas
1997
The assessment of discrepancies between surgical and histopathological measurements specimens is important in order to avoid repeat surgery unnecessary follow-ups.The objective this study was quantify the degree, time influential factors shrinkage cutaneous specimens.Data 111 patients were gathered on age, sex, localization, diagnosis specimen width length before excision (in vivo), at 5 min postsurgery (ex vivo) after 24 h fixation 10% buffered formalin (postfixation).The significantly...
Purpose. Previous studies have shown that melanoma cells produce excessive levels of cytokines, which various biological roles during development. The aim this study was to expand the profile serum chemokines, growth factors, and angiogenic factors are associated with melanoma, find more cytokines abnormal concentrations in patients, identify whether level correlated prognostic variants, such as Breslow thickness BRAF mutation, and, finally, out play important Materials Methods. Multiplex...
To determine possible mechanisms of action that might explain the nutrient partitioning effect betaine and conjugated linoleic acid (CLA) in Iberian pigs to address potential adverse effects, twenty gilts were restrictively fed from 20 50 kg BW Control, 0.5% betaine, 1% CLA or + diets. Serum hormones metabolites profile determined at 30 an oral glucose test was performed before slaughter. Pigs slaughtered livers obtained for chemical histological analysis. Decreased serum urea diets (11%; P...
Background: Lichen planopilaris (LPP) is a rare variant of cutaneous lichen planus that preferentially involves hair follicles.Observation: We describe the case an 87-year-old woman with cicatricial alopecia due to planopilaris.The diagnosis was based on clinical evaluation, histopathology and trichoscopy.Squamous cell carcinoma developed within hairless area after 18 years evolution. Conclusion:It necessary consider association between squamous ensure close follow-up LPP patients,...
The release and dynamics of macronutrients from decomposing leaf litter were determined for two deciduous oak species: one in Spain, Quercus pyrenaica, growing on a humic Cambisol (Sol brun forestier) the other France, Q lanuginosa, rendsic Leptosol (Rendzine).The same pro- cesses studied after leaf-litter exchanges between French stand Spanish stand.Nylon bags (1 mm 2 mesh), containing 10 g leaves, placed five stands (four Spain France) collected every months when they weighed analysed N,...
Scedosporium apiospermum is a filamentous fungus that can cause cutaneous or extracutaneous disease. A large number of cases have been published over the last decades, mainly in patients immunocompromised as result their disease treatment. These kinds infections progress rapidly and become disseminated, leading to very serious even fatal complications. We report two new skin infection by from our hospital.
We present the uncommon case of a subcutaneous fascia-based extramedullary plasmacytoma in leg, which was confirmed by pathology report and followed up until its remission. differential diagnosis with other more common soft tissue masses. Imaging findings are nonspecific but important to determine tumour extension plan biopsy.
Extramammary Paget disease (EMPD) is a very rare form of intraepithelial adenocarcinoma. We report the cases EMPD diagnosed in referral hospital over 5-year period from 2009 to 2013. Ten were 4 men and 6 women aged between 50 79 years. Erroneous clinical diagnoses led diagnostic delays 1 5 years all cases. Six patients had situ lesions dermal invasion was observed other Four second neoplasm 2 with invasive died. Because its presentation nonspecific, high degree suspicion required avoid...
Abstract Nodular lichen myxoedematosus is a localised form of myxoedematosus, chronic idiopathic cutaneous mucinosis known aetiology. Ustekinumab human interleukin‐12/23 monoclonal antibody that could directly or indirectly increase mucin production. Herein, we report for the first time case nodular associated with ustekinumab.
The influence of HLA class I and II loci on the susceptibility to melanoma remains an area intense debate. This study aimed examine whether system was related prognosis in a southern Spanish population. In this study, genotyping were performed using polymerase chain reaction sequence-specific oligonucleotides (PCR-SSO) 237 patients 636 ethnically matched controls. Data analyzed according clinical characteristics defined subgroups. Compared control group, DRB1∗16:01 (4% vs. 1.3%, p=0.001, Pc...
### Learning point for clinicians Mucocutaneous leishmaniasis is an increasingly common opportunistic infection that should be considered during treatment with mycophenolate mofetil, especially when other immunosuppressant drugs (such as corticosteroids) or diseases systemic lupus erythematosus) are present. Leishmaniasis infectious disease in which immunosupression a well-known risk factor its development. We report the first case of patient erythematosus (SLE) who was diagnosed...
Abstract Melanoma is one of the most aggressive forms human cancer and its incidence has significantly increased worldwide over last decades. This neoplasia been characterized by release a wide variety soluble factors, which could stimulate tumor cell proliferation survival in an autocrine paracrine manner. Consequently, we sought to evaluate pattern factors produced pre-metastatic metastatic melanoma established cultures, determine whether these can be detected autologous serum malignant...
3690 Background: Epidermal growth factor receptor (EGFR) is overexpressed in many types of cancers, especially colorectal cancer (CRC). Blocking EGFR activation represents an innovative strategy patient care but additional efforts are needed to establish better predictors the efficacy inhibitors. In present study, we evaluated and activated EGFR, such as phospho-EGFR, by immunohistochemistry (IHC) tissue microarrays (TMA) CRC patients analyzed their relationships with various clinical...