To investigate the prevalence of orthostatic hypotension and nature postural events related to a fall in blood pressure patients with Parkinson's disease.Blood was measured first supine position after rest at least 15 minutes every minute during 10 an active standing up procedure. Orthostatic considered as present when 20 mm Hg systolic recorded. Postural which occurred test were identified from questionnaire self reporting. Statistical analysis performed determine relation between disease...

Fast foods are quite popular among children owing to taste, appearance and hype created by mass media. However, the increased incidence of lifestyle disorders seen now-a-days at an early age could be attributed fast foods.This study was done assess awareness health hazards, consumption pattern find out its association with overweight high school students.This cross-sectional boys 3 private schools in Mangalore city March 2012.Data collected using a semi-structured self-administered...

Visual inspection of peripheral blood samples is a critical step in the leukemia diagnostic process. Automated solutions based on artificial vision approaches can accelerate this procedure, while also improving accuracy and uniformity response telemedicine applications. In study, we propose novel GBHSV-Leuk method to segment classify Acute Lymphoblastic Leukemia (ALL) cancer cells. two staged The first stage involves pre-processing, which uses Gaussian Blurring (GB) technique blur noise...

Breast cancer is a dreaded disease affecting women the most in cancer-related deaths over other cancers. However, early diagnosis of can help increase survival rates. The existing breast tools do not support disease. Therefore, there great need to develop diagnostic for this cancer. Photoacoustic spectroscopy (PAS), being very sensitive biochemical changes, be relied upon its application detecting tumors vivo. With motivation, current study, an aseptic chamber integrated photoacoustic (PA)...

Nanocomposite for comprehensive pharmacokinetic and antitumor potential using transferrin bypassing BBB anti-nestin antibody as a homing moiety against glioma.

Diagnosis of tuberculosis (TB) in resource-limited countries relies primarily on bacteriological confirmation using Ziehl-Neelsen (ZN) stain sputum or other representative samples. However, this method has low sensitivity due to suboptimal sampling and techniques. While AFB culture remains a gold standard for diagnosing TB mycobacterial infections, its limitations include slow turnaround time, the requirement specialized resources expertise. Neutrophils, monocytes, lymphocytes are crucial...

Abstract Introduction Endometrial carcinoma (EC) is the most common cancer in women (7% of all malignancies) standing fourth prevalence. Its molecular categorization has lately gained substantial importance, because its prognostic implications and association mismatch repair (MMR) proteins with Lynch syndrome. Objectives Our aim study was to analyze expression MMR (MLH1, PMS2, MSH6, MSH2) EC hyperplasia (EH). Materials Methods This performed on 52 65 EH cases (7 - disordered proliferative...

ABSTRACT Fine needle aspiration cytology (FNAC) is a cost‐effective, minimally invasive diagnostic tool requiring collaboration among pathologists, radiologists, nurses, and technicians for optimal outcomes. However, interprofessional remains limited, leading to delays reduced patient satisfaction. This study identifies the need an FNAC training module through comprehensive needs assessment stakeholders involved in service. Methods A mixed‐methods approach was used, comprising retrospective...

Urine cytology is an important screening tool of patients for urothelial carcinoma (UC) and follow-up with treated disease. Ease procurement, cost-effectiveness, lower turnaround time are the major advantages.

Interaction of polarized light with healthy and abnormal regions tissue reveals structural information associated its pathological condition. Even a slight variation in alignment can induce change polarization property, which play crucial role the early detection morphology. We propose transmission-based Stokes-Mueller microscope for quantitative analysis microstructural properties specimen. The based microscopy provides significant through various parameters such as degree (DOP), linear...

<b>Context:</b> Dysplastic changes are well documented in myelodysplastic syndromes (MDS). However, they also observed non-MDS hematological conditions.<b> Aims:</b> To evaluate the megakaryocytic alterations bone marrow aspirations cases of related thrombocytopenia. <b> Setting and Design: </b> A prospective study 144 aspirates was conducted department pathology, Kasturba Medical College, Mangalore. The were studied to assess number morphology megakaryocytes thrombocytopenia their...

Rheumatic fever (RF) is an important problem concerning developing countries like India. heart disease (RHD) one of the most readily preventable chronic diseases.This study was done to find out clinical profile, risk factors, compliance with treatment and outcome among RF/RHD cases so as suggest better case management strategies.Clinical records 51 RF 71 RHD admitted in tertiary care hospitals Mangalore between 2001 2010 were reviewed retrospectively.Mean age 17.4 ± 12.1 years 33.2 18.6...

Knowledge of community medicine is essential for health care professionals to function as efficient primary physicians. Medical students learning Community Medicine a subject are expected be competent in critical thinking and generic skills so analyze problems better. However, current teaching by didactic lectures fails develop these skills. Problem-based (PBL) could an effective strategy this respect. This study was hence done compare the academic performance who were taught PBL method with...

The aim of the study is to compare histologic quality microwave histoprocessing with that conventional method and determine its positive impact on turnaround times reduction costs tissue processing. One hundred eighty-five paired sections from different organs were taken. Each size 15 mm × 10 3 divided into two; one set as experimental group other control group. tissues in further six groups processed by vacuum-microwave according protocols I VI. Other compared. Overall, microscopic both...

In the current study, a breast tumor xenograft was established in athymic nude mice by subcutaneous injection of MCF-7 cell line and assessed progression photoacoustic spectroscopy combined with machine learning tools. The advancement tumors validated volume kinetics histopathology corresponding image analysis TissueQuant software compared to controls. ex vivo progressive conditions belonging time points, day 5th, 10th, 15th & 20th, were excited 281 nm pulsed laser light recorded spectra...

Sudden unexplained deaths, especially those unwitnessed can lead to forensic issues and would necessitate the need for a meticulous complete postmortem examination including ancillary investigations discover cause of death. We herein report case sudden death caused by malaria in an apparently healthy individual. This fatal is presented remind pathologist possibility as malaria-endemic regions. In present case, histopathological demonstrated presence parasitized red blood cells with malarial...

Sir, Gouty tophi presenting as periarticular masses are uncommon and often mistaken for a neoplasm. These nodules may not be recognized because the clinical diagnosis of gout in many instances is straightforward. In such setting, fine needle aspiration cytology (FNAC) gouty would facilitate treatment. We report one case. A 52-year-old male came to surgical outpatient department with painful swellings near elbow ankle joint. On examination, two firm, immobile were seen subcutaneous plane, on...

Extramedullary plasmacytoma (EMP) constitutes approximately 4% of all plasma cell neoplasms. It may present as the sole manifestation neoplasm, a solitary bone or consequence multiple myeloma. This study was done to determine role fine needle aspiration cytology (FNAC) in diagnosis EMP.In our 8 cases EMP at various sites were diagnosed on FNAC. In 3 patients initial presentation neoplasm. remaining 5 tumors occurred during course treatment for myeloma.The lesions located anatomic sites,...

<ns7:p>Background The Coronavirus disease-19 (COVID-19) infection of severe acute respiratory syndrome coronavirus-2 (SARS-Cov-2) has emerged as a recent pandemic, increasing the need for epidemiological studies and on public health. Only some have evaluated awareness medical undergraduates in India other countries, leading to lack literature. Methods This study is descriptive cross-sectional questionnaire-based conducted Kasturba Medical College, Mangalore, India, between June August 2020....

Endometrial Carcinoma (EC) is the most common gynecological cancer with a global incidence of 23.2 per 1 lakh population. Histological subclassification EC extremely crucial for diagnosis, proper management strategies, and prognosis. This study was conducted in tertiary care institute to analyze expression pattern minimum panel 4 markers (ER, p53, CEA, Napsin A) emphasis on their utility routine histological subtyping, aberrant expression, correlation various clinicopathological parameters.

Background: Ancient schwannoma is a rare subtype of characterized by an extended duration development and distinctive degenerative changes. These changes encompass relative loss Antoni type A areas, perivascular hyalinization, hemorrhage, cystic necrosis, calcification, the presence atypical nuclei that can mimic sarcomatous pleomorphism. histologic features often lead to diagnostic challenges, with ancient schwannomas frequently being misdiagnosed as malignant tumors. Objectives: This study...