- Functional Brain Connectivity Studies
- Mental Health Research Topics
- Stress Responses and Cortisol
- Psychosomatic Disorders and Their Treatments
- Suicide and Self-Harm Studies
- Psychopathy, Forensic Psychiatry, Sexual Offending
- Neural dynamics and brain function
- Neural and Behavioral Psychology Studies
- Advanced MRI Techniques and Applications
- Advanced Neuroimaging Techniques and Applications
- EEG and Brain-Computer Interfaces
- Tryptophan and brain disorders
- Neuroscience and Neuropharmacology Research
- Homicide, Infanticide, and Child Abuse
- Terrorism, Counterterrorism, and Political Violence
- Physical Education and Training Studies
- Gun Ownership and Violence Research
- Death Anxiety and Social Exclusion
- Sexual function and dysfunction studies
- Optical Imaging and Spectroscopy Techniques
- Mental Health Treatment and Access
- Bullying, Victimization, and Aggression
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Posttraumatic Stress Disorder Research
- COVID-19 and Mental Health
Otto-von-Guericke University Magdeburg
2019-2024
Salus Klinik
2020
University Hospital Magdeburg
2020
Klinikum Magdeburg
2020
Deficits in reward learning are core symptoms across many mental disorders. Recent work suggests that such impairments arise by a diminished ability to use history guide behaviour, but the neuro-computational mechanisms through which these emerge remain unclear. Moreover, limited has taken transdiagnostic approach investigate whether psychological and neural give rise deficits shared forms of psychopathology. To provide insight into this issue, we explored probabilistic patients diagnosed...
Abstract The brain's default mode network (DMN) and the executive control (ECN) switch engagement are influenced by ventral attention (VAN). Alterations in resting‐state functional connectivity (RSFC) within this so‐called triple have been demonstrated patients with major depressive disorder (MDD) or anxiety disorders (ADs). This study investigated alterations RSFC comorbid MDD ADs to better understand pathophysiology of prevalent group patients. Sixty‐eight participants (52.9% male, mean...
Major Depression (MDD) and anxiety disorders are stress-related that share pathophysiological mechanisms. There is evidence for alterations of glutamate-glutamine, N-acetylaspartate (NAA) GABA in the anterior cingulate cortex (ACC), a stress-sensitive region affected by hypothalamic-pituitary-adrenal axis (HPA). The aim was to investigate metabolic ACC whether hair cortisol, current stress or early life adversity predict them.We investigated 22 patients with MDD comorbid disorder 23 healthy...
Personality, psychopathology, and motives of 44 surviving offenders committing mass murder in Germany over 25 years (1984–2009) were analyzed using court files psychiatric expertises. Initially, 123 murders detected the time period 1980–2010 (inclusive deceased offenders). Using a data entry form based on ViCLAS (Violent Crime Linkage Analysis System), we categorized murderers into three prototypes 'TwoStep Cluster'-method (separation different groups depending their similarity specific...
Abstract Aggression occurs across the population ranging on a symptom continuum. Most previous studies have used magnetic resonance imaging in clinical/forensic samples, which is associated with several confounding factors. The present study examined structural brain characteristics two healthy samples differing only their propensity for aggressive behavior. Voxel- and surface-based morphometry (SBM) analyses were performed 29 male martial artists 32 age-matched controls. Martial had...
Abstract Objectives The direct exertion as well the visual perception of violence can have a hedonistic effect and elicit positive arousal in predisposed individuals. This appetitive aspect aggression healthy subjects has been neglected psychiatric research so far. Methods Using functional magnetic resonance imaging, we tested whether trained sports with violent component (martial arts) show altered brain responses reward‐associated areas when compared to controls. Sixteen martial artists...
The brain‘s default mode network (DMN) and the executive control (ECN) switch engagement influenced by ventral attention (VAN). Alterations in resting-state functional connectivity (RSFC) within this so-called triple have been demonstrated patients with major depressive disorder (MDD) or anxiety disorders (AD). This study investigated alterations RSFC comorbid MDD ADs to better understand pathophysiology of prevalent group patients. Sixty-eight participants (52.9 % male, mean age 35.25...
Introduction Perception and practice of violence have hedonistic aspects that are associated with positive arousal (appetitive aggression). Earlier studies primarily investigated the etiology aggressive behavior in forensic psychiatric samples. To deal possible confounds (e.g. hospitalization, co-morbidities), present study examined structural brain characteristics healthy people inclined to (martial artists) comparison controls not showing violent behavior.