A5056997523- Traditional and Medicinal Uses of Annonaceae
- Alkaloids: synthesis and pharmacology
- Natural product bioactivities and synthesis
- Phytochemistry and Biological Activities
- Mosquito-borne diseases and control
- Berberine and alkaloids research
- Chemical synthesis and alkaloids
- Insect Pest Control Strategies
- Education and Digital Technologies
- Light effects on plants
- Handwritten Text Recognition Techniques
- Mercury impact and mitigation studies
- Radioactivity and Radon Measurements
- Bioactive natural compounds
- Advanced Chemical Sensor Technologies
- Phytochemicals and Antioxidant Activities
- Various Chemistry Research Topics
- Heavy metals in environment
- Image Processing and 3D Reconstruction
- Chromatography in Natural Products
- Digital Media Forensic Detection
- Microbial Metabolic Engineering and Bioproduction
- Thyroid Disorders and Treatments
- Enzyme Catalysis and Immobilization
- Business and Management Studies
Universidade Federal do Rio de Janeiro
2014-2025
Laboratory cultivation experiments were conducted under soil contamination using fluorescent lamps (50 and 100 mg kg–1 of Pb) to observe the seed germination growth tomatoes (Lycopersicum esculentum Miller) over 60, 90, 120 days. The parameters selected evaluate impact on plant development included survival rates, morphological characteristics such as production root, stem, leaf tissues (masses), well changes in chemical profile, with a focus polyphenolic content leaves. Tomato was...
Uncaria tomentosa (Willd.) DC. and U. guianensis (Aubl.) Gmel., known as cat's claw, are large woody vines native to the Amazonian Central American rainforests. The species contain, in different proportions, indole oxindole alkaloids, triterpenoid glycosides, sterols proanthocyanidins. can be chemically identified by its alkaloid profile content, whereas has no satisfactorily established chemical markers. This work describes, for first time, isolation of kaempferol-3,7-O-(α)-dirhamnoside...
The methanol (MeOH) leaf extracts of the species Faramea bahiensis, F. hyacinthina and truncata (Rubiaceae) have previously shown in vitro non-cytotoxic anti-dengue virus serotype 2 (DENV2) activities human hepatocarcinoma cell lineage (HepG2). Chemical studies led to isolation major flavonoids, but quite complex fractions phenolic compounds still remain.To complete study leaves access presence these stems spp. by online high-performance liquid chromatography-diode array...
The defatted fractions of the Faramea hyacinthina and F. truncata (Rubiaceae) leaf MeOH extracts showed in vitro non-cytotoxic anti-dengue virus serotype 2 (DENV2) activity human hepatocarcinoma cell lineage (HepG2). Submitting these to developed RP-SPE method allowed isolating antiviral flavanone (2S)-isosakuranetin-7-O-β-d-apiofuranosyl-(1→6)-β-d-glucopyranoside (1) from both species yielded less active sub-fractions. new diastereoisomeric epimer pair (2S) + (2R)...
The leaf MeOH extract of Psychotria leiocarpa (Rubiaceae) showed in vitro non-cytotoxic and anti-dengue virus serotype 2 (DENV2) activity human hepatocarcinoma cell lineage (HepG2).A one-step cost-effective reversed-phase solid-phase extraction method based on high-performance liquid chromatography (HPLC) parameters allowed the isolation, directly from this bioactive extract, monoterpene indole alkaloids: N-glucopyranosyl vincosamide (1), (2) strictosidinic acid (3).The chemical structures...
A simple and low-cost solid-phase extraction methodology for isolating the bioactive flavonoid kaempferitrin from a defatted fraction of Uncaria guianensis leaf ethanol extract was developed using retention behavior in reversed-phase-high-performance liquid chromatography as well thin-layer coupled to ImageJ software (Bethesda, USA) densitometric analyses. In addition, method enabled isolation less-complex mixtures further separation minor constituents. The target compound successfully...
With the primary objective of transitioning from classical iodometric method to an instrumental approach, preserving precision in analytical process, this study presents development a spectrophotometric for quantifying iodate (iodine equivalent) nutritionally significant salts. Therefore, wavelengths maximum absorption I3- (350.8 nm) and I3-starch (574.1 complexes were determined. The demonstrated stability, as indicated by respective molar extinction coefficient values (ε) obtained over...
The Amazonian Rubiaceae species Uncaria guianensis (UG) is locally used as antiinflammatory, antitumor, antidiabetic, anti-ulcers, and others. phenolic content of its leaves characterized by the great predominance flavonoid kaempferol-3,7-O-(α)-L-dirhamnoside (kaempferitrin). present study quantitatively evaluates kaempferitrin in branches cultivated wild UG specimens collected different locations Brazilian Amazon rainforest employing high-performance liquid chromatography coupled to a diode...
Dengue virus infection is a neglected disease prevalent in most tropical and subtropical areas. Currently there no vaccine or any antiviral drug indicated for the routine treatment of dengue patients. As part our ongoing search potential anti-dengue agents we have investigated MeOH extracts from leaves three Brazilian species genus Faramea (Rubiaceae). The vitro cytotoxic serotype 2 effects were measured human hepatocarcinoma cell lineage (HepG2). HepG2 cells infected at multiplicity (MOI) 1...
An anti-DENV-2 flavanone glycoside (1) was previously isolated from the leaf methanol extract of Faramea hyacinthina Mart. (Rubiaceae) by liquid-liquid partition followed Sephadex LH-20 and reversed-phase (C18) CC [1]. The search for development effective methodologies purifying large amounts target natural compounds further studies or applications is an ongoing challenge. In this work a simple low-cost method isolating bioactive SPE developed on basis HPLC conditions [2]. polyphenolic-rich...
Abstract Documentoscopy is a specialized field in criminalistics that verifies the authenticity of suspect documents during fraud investigations, providing crucial forensic evidence. Traditional documentoscopy relies on costly scanning electron microscopy (SEM), subject to bias, with an accuracy about 63% determining stroke sequences. Recent advancements led cost-effective alternatives. Using Computer Vision (CV) and Convo-lutional Neural Networks (CNN), prototype was developed identify...
A large amount of seed cake is generated as a by-product during biodiesel production from physic nut (Jatropha curcas). This material has high protein and fiber content, which make them interesting for use livestock feed. However the presence toxic phorbol esters (PE) restricts its [1]. In previous study Brazilian Jatropha was used cultivation medium Penicillium simplicissimum in solid-state fermentation (SSF) to obtain lipase simultaneous detoxification [2]. this order contribute...
Uncaria guianensis (UG) (Rubiaceae) is a species widely used in traditional medicine. The EtOH extract of their leaves has demonstrated anti-inflammatory and anti-allergic activities. In this work Semi-Prep-HPLC was employed to separate the polyphenolic compounds present UG leaf by applying chromatographic models. Polyphenolic enriched fractions previously obtained RP-CC were analyzed an Inertsil Prep-ODS column (250×6mm, 10µm), 30°C, flow rate 1.4 mL/min, isocratic mode CH3CN:H2O at five...
A importância do trabalho colaborativo e transdisciplinar na educação a distância.