A5031570880- Colorectal Cancer Surgical Treatments
- Colorectal Cancer Screening and Detection
- Extracellular vesicles in disease
- Colorectal and Anal Carcinomas
- MicroRNA in disease regulation
- Gastric Cancer Management and Outcomes
- Circular RNAs in diseases
- Anodic Oxide Films and Nanostructures
- Cardiac, Anesthesia and Surgical Outcomes
- Urinary Tract Infections Management
- Electrolyte and hormonal disorders
- Anorectal Disease Treatments and Outcomes
- Streptococcal Infections and Treatments
- Bacterial Identification and Susceptibility Testing
- Sepsis Diagnosis and Treatment
- Neonatal and Maternal Infections
- Bladder and Urothelial Cancer Treatments
- Prostate Cancer Diagnosis and Treatment
- Pancreatic and Hepatic Oncology Research
- Gut microbiota and health
- High-Temperature Coating Behaviors
- Renal function and acid-base balance
- Bariatric Surgery and Outcomes
- Pediatric Urology and Nephrology Studies
- Esophageal and GI Pathology
First Affiliated Hospital of Jiangxi Medical College
2024-2025
Nanchang University
2022-2025
First Affiliated Hospital of Nanchang University
2022-2023
Second Affiliated Hospital of Nanchang University
2023
The tumor microenvironment (TME) is a dynamic system orchestrated by intricate cell-to-cell crosstalk. Specifically, macrophages within the TME play crucial role in driving progression. Exosomes are key mediators of communication between cells and TME. However, mechanisms underlying exosome-driven crosstalk during colorectal cancer (CRC) progression remain incompletely elucidated.
This study aimed to determine the optimal natural orifice specimen extraction (NOSE) method for robotic-assisted mid-rectal cancer resection in women. retrospective propensity score-matched (PSM) was analyze clinical data prospectively collected from female rectal patients who underwent either transvaginal (RATV) or transanal (RATA) at our center between June 2016 and December 2022. The main outcome measures were urinary, anal, sexual function. Disease-free survival (DFS), overall (OS) also...
Metastasis is the leading cause of mortality for colorectal cancer (CRC). Cancer-derived exosomes are widely recognized as primary catalysts behind development pre-metastasis niche (PMN) in distal sites. However, exact mechanism this process CRC remains elusive. This study aimed to investigate function and mechanisms underlying role exosomal miR-188-3p activating hepatic stellate cells (HSCs) develop PMN promote liver metastasis. We extracted from using ultracentrifugation. Exosomes were...
Abstract Background and Aim The dysbiosis of gut microbiota has been reported in acute pancreatitis. However, the direction magnitude between host pancreas remains to be established. This study investigated association pancreatitis using Mendelian randomization (MR) methods. Methods Summary statistics abundance were extracted from genome‐wide studies (GWAS). two‐sample bidirectional MR design was employed assess genetic pancreatitis, followed by a comprehensive sensitivity analysis verify...
The treatment strategy for stage II rectal mucinous adenocarcinoma (RMA) recommends neoadjuvant chemoradiotherapy (NCR) followed by total mesorectal excision (TME). However, the necessity of adjuvant chemotherapy (AC) remains controversial. Chi-square test was used to assess relationship between pathological classification, AC and clinicopathological characteristics. Kaplan-Meier (KM) curves log-rank were utilized analyze differences in overall survival (OS) cancer-specific (CSS) among...
Abstract Cancer cells exhibit heterogeneous metastatic potential, and high (HM) subclones can enhance the potential of low by transmitting some factors. Exosomal miRNAs play a pivotal role in crosstalk subclones. This study discovered that miR-20a-3p was upregulated colorectal adenocarcinoma (CRA), correlated with metastasis, potentially served as prognostic indicator for CRA. could promote proliferation, migration, invasion CRA cells. Interestingly, HM malignant phenotypes exosomal...
To assess whether serum chloride predicts risk of death in intensive care unit (ICU) patients with heart failure (HF) and the effect bicarbonate on efficacy predicting ICU patients.
To investigate the clinical diagnostic value of differential flora as biomarkers in patients with symptomatic urinary tract infection (UTI) and asymptomatic bacteriuria (ASB) undergoing cutaneous ureterostomy based on metagenomic next-generation sequencing construct predictive models to provide a scientific reference for diagnosis treatment. Material Methods. According standard procedures, samples were taken from each patient routine tests (urine, ureteral stent, skin swab around stoma)....
Abstract Background With the improvement of anastomotic techniques and iteration instruments, robotic intracorporeal suturing has become increasingly proficient. The era fully anastomosis in gastric cancer resection is emerging. This study aims to explore impact totally distal gastrectomy (TRDG) robotic-assisted (RADG) on patients' quality life survival. Patients Methods a comparative retrospective propensity score matching. included 306 patients who underwent for between June 2016 December...
Group B streptococcus(GBS)often causes adverse outcomes such as urinary system infection, intrauterine premature birth, and stillbirth in perinatal women. Perinatal screening of GBS is conducive to guiding clinical scientific intervention improving delivery outcomes.This study quantitative real-time PCR (RT-qPCR) combined with magnetic separation was used for detection.