A5031839908- Mesenchymal stem cell research
- Electrospun Nanofibers in Biomedical Applications
- Tissue Engineering and Regenerative Medicine
- Cytokine Signaling Pathways and Interactions
- Hematopoietic Stem Cell Transplantation
- Hydrogels: synthesis, properties, applications
- Neuroendocrine regulation and behavior
- Lymphatic System and Diseases
- Cellular Mechanics and Interactions
- Pluripotent Stem Cells Research
- Cancer Cells and Metastasis
- Muscle Physiology and Disorders
- Stress Responses and Cortisol
- 3D Printing in Biomedical Research
- Tryptophan and brain disorders
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Alzheimer's disease research and treatments
Tulane University
2020-2024
Louisiana Tech University
2019-2020
The growth and differentiation of adipose tissue-derived stem cells (ASCs) is stimulated regulated by the tissue (AT) microenvironment. In lipedema, both inflammation hypoxia influence expansion ASCs, resulting in hypertrophic adipocytes deposition collagen, a primary component extracellular matrix (ECM). goal this study was to characterize adipogenic potential assess levels expression ECM-remodeling markers 3D spheroids derived from ASCs isolated lipedema healthy individuals. data showed an...
Noradrenergic afferents to hypothalamic corticotropin releasing hormone (CRH) neurons provide a major excitatory drive the hypothalamic-pituitary-adrenal (HPA) axis via α1 adrenoreceptor activation. are recruited preferentially by somatic, rather than psychological, stress stimuli. Stress-induced glucocorticoids feed back onto hypothalamus negatively regulate HPA axis, providing critical autoregulatory constraint that prevents glucocorticoid overexposure and neuropathology. Whether negative...
Three-dimensional (3 D) hydrogel scaffolds are an attractive option for tissue regeneration applications because they allow cell migration, fluid exchange, and can be synthesized to closely mimic the physical properties of extracellular matrix environment. The material hydrogels play a vital role in cellular migration differentiation. In light this, in-depth understanding is required before such used study their influence on cells. Herein, various blends thicknesses poly (ethylene glycol)...
Human adipose-derived stem cells (ASCs) show immense promise for treating inflammatory diseases, attributed primarily to their potent paracrine signaling. Previous investigations demonstrated that short-term Rapamycin preconditioning of bone marrow-derived (BMSCs) elevated secretion prostaglandin E2, a pleiotropic molecule with therapeutic effects in the experimental autoimmune encephalomyelitis (EAE) model multiple sclerosis (MS), and enhanced immunosuppressive capacity vitro. However, this...
Abstract Background Alzheimer’s Disease (AD) is a prevalent age‐related neurodegenerative condition leading to dementia, yet factors regulating its polygenomic etiology and progression remain elusive. MicroRNAs (miRNAs), small RNA molecules protein expression, play role in neurodegeneration. MicroRNA‐34a (miR‐34a) crucial regulator of numerous genes associated with disorders, aggregation synaptic transmission genes. However, the lack effective tools for vivo study impedes comprehensive...