A5027650066- SARS-CoV-2 detection and testing
- SARS-CoV-2 and COVID-19 Research
- Neonatal and fetal brain pathology
- Advanced Neuroimaging Techniques and Applications
- Fetal and Pediatric Neurological Disorders
- COVID-19 Clinical Research Studies
- Respiratory viral infections research
University Hospital Cologne
2022
University of Cologne
2022
Article abstract—The syndrome of autosomal recessive pontocerebellar hypoplasia, microcephaly, severely impaired mental and motor development, extrapyramidal dyskinesia is a distinct system degeneration, previously designated hypoplasia type 2 (PCH-2). To further characterize its clinical neuroimaging features, we compiled data from 10 nonrelated pedigrees. Six pedigrees were Dutch, two Swedish, German. All 16 patients showed an identical profile virtually absent developmental milestones,...
Abstract Systematic SARS-CoV-2 testing is a valuable tool for infection control and surveillance. However, broad application of high sensitive RT-qPCR in children often hampered due to unpleasant sample collection, limited capacities costs. Here, we developed high-throughput approach (‘Lolli-Method’) detection children, combining non-invasive collection with an RT-qPCR-pool strategy. infections were diagnosed sensitivities 100% 93.9% when viral loads >10 6 copies/ml 3 corresponding...
Abstract Systematic SARS-CoV-2 testing is a valuable tool for infection control and surveillance. However, broad application of high sensitive RT-qPCR in children often hampered due to unpleasant sample collection, limited capacities costs. Here, we developed high-throughput approach (‘Lolli-Method’) detection children, combining non-invasive collection with an RT-qPCR-pool strategy. infections were diagnosed sensitivities 100% 93.9% when viral loads >10 6 copies/ml 3 corresponding...