A5002976577- Growth Hormone and Insulin-like Growth Factors
- Helicobacter pylori-related gastroenterology studies
- Phytochemistry and biological activity of medicinal plants
- Neuropeptides and Animal Physiology
- Inflammatory Bowel Disease
- Bone Metabolism and Diseases
- Pharmacological Effects of Natural Compounds
- Gut microbiota and health
- Regional Development and Environment
- Ginseng Biological Effects and Applications
First Affiliated Hospital of Jinan University
2024-2025
Jiaxing University
2018
To synthesize a puerarin nanoparticle based on glycyrrhetinic acid (GA)-PEG-PBLA and evaluate it in vivo.In this study, drug was synthesized, characterized assessed as delivery system. Nanoparticle GA-PEG-PBLA could combine with via hydrophobic interaction to form the compound. Puerarin be quickly efficiently loaded at pH 7.4. Further, GA-PEG-PBLA-mediated system target for liver that had GA receptor binding. The antiliver ischemia/reperfusion injury role of puerarin/GA-PEG-PBLA measured...
Drynariae Rhizoma (DR) has been commonly used as a preventive and therapeutic agent for bone diseases. However, its pharmacological mechanisms have not fully elucidated. Here, we aimed to investigate the effects of DR in bilateral ovariectomized (OVX) rat model explore correlation with gut microbiome. We established an OVX treated different doses (DR-L, 0.27 g/kg/day; DR-M, 0.81 DR-H, 2.43 g/kg/day) through intragastric administration 12 weeks. Results showed that alleviated body weight,...