David Chukwuma Nwikwe

ORCID: 0000-0002-7214-8149
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About
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Research Areas
  • Herbal Medicine Research Studies
  • Computational Drug Discovery Methods
  • Drug-Induced Hepatotoxicity and Protection
  • Piperaceae Chemical and Biological Studies
  • Insect Pest Control Strategies
  • Moringa oleifera research and applications
  • Pharmacological Effects of Natural Compounds
  • Heavy Metal Exposure and Toxicity
  • Mosquito-borne diseases and control
  • Synthesis and bioactivity of alkaloids
  • Malaria Research and Control

University of Ilorin
2023-2024

Although herbal medicines are less potent compared to synthetic drugs in some cases, but still considered toxic side effects. Cryptolepis sanguinolenta stem ethanol extract (CSSE) is a reportedly antimalarial plant with dearth of data on the safety and efficacy brain heart animals. This study evaluated CSSE animal models. Thirty albino rats were randomly distributed into five groups (n=6). Group A=distilled water (control), Groups B-E=250, 500, 1000, 2000 mg/kg body weight extract,...

10.4314/ijs.v26i3.4 article EN other-oa Deleted Journal 2025-01-23

Traditional water purification methods are increasingly inadequate, leading to the exploration of novel approaches. This study investigated application plant-derived nanomaterials for heterogeneous photocatalytic treatment using ZnO-Vernonia amygdalina nanoparticles (ZVAN). The evaluated efficacy ZVAN in purifying Asa River (ARW) and assessed its toxicological profile rats. Synthesized was characterized by X-ray diffraction (XRD) scanning electron microscopy (SEM). ARW samples were collected...

10.1016/j.sciaf.2023.e02050 article EN cc-by Scientific African 2023-12-21

A potential antimalarial prospect should have high efficacy with low toxicity. SynriamTM drug has been proven to be safe and effective for the treatment of malaria in human dearth information on rats. This study investigated its toxicity from prolonged administration lipid profiles haematological indices Thirty-five Wistar rats were randomized into five groups (A – E) seven each. Animals group (control) received 0.5 mL distilled water, while B, C, D, E respectively 4.0, 8.0, 16.0 32.0 mg/kg...

10.26538/africanscientist.24.2.202306012 article EN African Scientist 2023-06-30
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