- Dermatology and Skin Diseases
- Food Allergy and Anaphylaxis Research
- Contact Dermatitis and Allergies
- Nonmelanoma Skin Cancer Studies
- Infectious Diseases and Mycology
- Cancer and Skin Lesions
- Thermal Regulation in Medicine
Princess Alexandra Hospital
2023
Bond University
2022
Gold Coast Hospital
2022
Vanderbilt University
2002
Royal London Hospital
1989
The main carcinogen for keratinocyte skin cancers (KCs) such as basal and squamous cell carcinomas is ultraviolet (UV) radiation. There growing evidence that accumulation of mutations clonal expansion play a key role in KC development. relationship between UV exposure, epidermal mutation load, KCs remains unclear. Here, we examined the load both murine (n = 23) human 37) samples. Epidermal accumulated dose-dependent manner, this correlated with burden. ablation (either mechanical or laser...
lymphocytes with scattered eosinophils.A second skin biopsy showed epidermal detachment abundant eosinophils, consistent TEN or severe contact dermatitis.All other investigations were all unremarkable.The eruption subsequently progressed to full thickness necrosis denudation, requiring admission the burns unit where he was treated supportive care.The patient ultimately made a complete recovery without ensuing sequelae of event.Conclusion: ICD causing an EM-like reaction is rare, and only...