A5088098054- Colorectal Cancer Surgical Treatments
- Colorectal and Anal Carcinomas
- Gastric Cancer Management and Outcomes
- Colorectal Cancer Treatments and Studies
- Colorectal Cancer Screening and Detection
- Gastrointestinal Tumor Research and Treatment
- Metastasis and carcinoma case studies
- Cancer Immunotherapy and Biomarkers
- Tracheal and airway disorders
- Prostate Cancer Diagnosis and Treatment
- Prostate Cancer Treatment and Research
- Appendicitis Diagnosis and Management
- Surgical Simulation and Training
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Gastrointestinal disorders and treatments
- Medical Imaging and Pathology Studies
- Medical Imaging and Analysis
- Hernia repair and management
- Cardiac tumors and thrombi
- Lymphatic Disorders and Treatments
- Anatomy and Medical Technology
- Adrenal Hormones and Disorders
- Diagnosis and treatment of tuberculosis
- Venous Thromboembolism Diagnosis and Management
- Viral-associated cancers and disorders
Toranomon Hospital
2015-2025
Kyoto University
2018-2023
Chiba University
2023
Kyoto University Hospital
2009
The programmed death‐1/programmed death‐ligand 1 ( PD ‐L1) pathway is a negative feedback that suppresses the activity of T cells. Previous studies reported high ‐L1 expression on tumor cells TC ) was associated with poor survival in patients colorectal cancer; however, prognostic evaluation these limited because they included at various disease stages. purpose present study to evaluate relationship between status immune microenvironment and clinicopathological features stage III cancer. Two...
Abstract Background Artificial intelligence (AI) has the potential to enhance surgical practice by predicting anatomical structures within field, thereby supporting surgeons' experiences and cognitive skills. Preserving utilising nerves as critical guiding is paramount in rectal cancer surgery. Hence, we developed a deep learning model based on U-Net automatically segment nerves. Methods The performance was evaluated using 60 randomly selected frames, Dice Intersection over Union (IoU)...
Abstract We aimed to develop an AI model that recognizes and displays loose connective tissue as a dissectable layer in real-time during gastrointestinal surgery evaluate its performance, including feasibility for clinical application. Training data were created under the supervision of surgeons. Test images videos randomly sampled performance was evaluated visually by 10 external The mean Dice coefficient 50 0.46. could detect at least 75% 91.8% (459/500 responses). False positives found...
In high-risk patients undergoing surgery for colorectal cancer with organ invasion, a thorough evaluation of surgical indications and careful selection optimal approaches is essential. We report case advanced transverse colon gastric invasion in 58-year-old male Child-Pugh grade B liver cirrhosis. The patient underwent laparoscopic colectomy combined wedge resection. Intraoperative upper gastrointestinal endoscopy facilitated precise primary tumor was excised clear margin, the postoperative...
The prognostic nutritional index (PNI) based on the serum albumin level and lymphocyte count has been investigated as a factor in patients with malignant tumors. However, it poorly studied prostate cancer (PCa), little is known about its clinical utility.Clinical data of 353 de novo, metastatic, hormone-sensitive PCa (mHSPC) who received androgen deprivation therapy (ADT) were obtained from multiple institutions between 2000 2019. impacts pretreatment PNI treatment response survival,...
As laparoscopic surgery has become the mainstream technique for abdominal surgery, it difficult surgical residents to have opportunities perform open surgery. This study aimed examine appropriateness and feasibility of appendectomy performed by trainees who had little experience with or training animal models.We retrospectively reviewed all records patients underwent acute appendicitis from April 2008 December 2014. Residents were assigned two levels seniority: junior undergone 1-3 years...
Colorectal cancer seldom presents at the splenic flexure. Small series on left flexure tumors reported a high occurrence of negative prognostic factors called into question as causes poor prognosis. However, because small number cases, no definite conclusions can be drawn.The aim this study was to compare clinical-pathologic characteristics and short- long-term outcomes with other colonic locations.This retrospective analysis consecutive patients who underwent surgery for Each tumor paired...
FOLFOX and panitumumab combined chemotherapy plays an important role for metastatic colorectal cancer. However the usefulness of this regimen neoadjuvant therapy is unclear. A 67-year-old man with abdominal pain pneumaturia was diagnosed RAS wild-type sigmoid colon cancer urinary bladder invasion colovesical fistulas. Because considered to be unresectable, a transverse-loop colostomy performed. Colonoscopy computed tomography revealed marked reduction in size primary tumor after six courses...
Inguinal hernias account for 75 % of abdominal wall hernias, with a lifetime risk 27 in men and 3 women. Major complications are recurrence, chronic pain, surgical site infection, but their frequency is low. Few studies have reported calcified mesh causing neuropathy by compression the femoral nerve after & plug inguinal hernia repair. This first report laparoscopic removal colic due to irritation cause In July 2013, 53-year-old man presented our hospital chief complaint pain left lower limb...
A 53-year-old man was readmitted with abdominal distention 2 weeks after undergoing laparoscopic low anterior resection para-aortic lymphadenectomy for advanced rectal cancer (T4aN1M0, Stage IIIb). Ultrasound revealed massive ascites, and paracentesis chylous fluid a markedly elevated triglyceride level (1762 mg/dL). Despite conservative management, the fistula remained on postoperative day 120. On percutaneous lymphangiography, leakage point clearly visualized at site, surgical intervention...
The development of transplantation technology has improved the prognosis surgery; however, negative impact immunosuppressive drugs increased number patients with cancer after transplantation. Recently, minimally invasive surgery become more common for treatment. We report our experience performing laparoscopic sigmoid colon resection a patient history two renal transplantations and peritoneal dialysis. A 42-year-old male who developed purpura nephropathy underwent at ages eight 34 years. He...
Intensive localized therapy is promising for the treatment of rectal cancer. In Japan, chemoradiotherapy (CRT) and neoadjuvant chemotherapy (NAC) are used as preoperative treatments this disease. Magnetic resonance imaging (MRI) to diagnose lateral pelvic node (LPN) metastases, but changes in LPN findings on MRI following unclear. Furthermore, there may be patients whom dissection can omitted after CRT/NAC.
Surgical treatment of splenic flexure cancer (SFC) still presents some debated issues, including the role laparoscopic surgery. The literature is based on small single-centre series, while randomized controlled studies comparing open and for colon exclude SFC. This study aimed to determine surgery in SFC, short- long-term outcomes with surgery.This was an international multicentre retrospective cohort that analysed patients from 10 tertiary referral centres. From a 641 cases, 484 Stage I-III...
611 Background: Programmed death 1 (PD-1)/ PD-L1 pathway is a negative feedback mechanism that suppresses the activity of T cells. Some previous studies showed positive expression on tumor cells (TC) was poor prognostic factor in patients with colorectal cancer; however, recent suggest IC also play important roles to determine prognosis cancer patients. The aim this study investigate association clinical and pathological features TC IC. Methods: We retrospectively reviewed data consecutive...