- Asthma and respiratory diseases
- Climate Change and Health Impacts
- Global Health Care Issues
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Respiratory Support and Mechanisms
- Inhalation and Respiratory Drug Delivery
- Pneumonia and Respiratory Infections
- COVID-19 Clinical Research Studies
- Air Quality and Health Impacts
- Smoking Behavior and Cessation
- Diverticular Disease and Complications
- Obesity and Health Practices
- Urinary and Genital Oncology Studies
- Allergic Rhinitis and Sensitization
- Diagnosis and treatment of tuberculosis
- Global Public Health Policies and Epidemiology
- School Health and Nursing Education
- Urologic and reproductive health conditions
- Intestinal and Peritoneal Adhesions
- SARS-CoV-2 and COVID-19 Research
- Sarcoma Diagnosis and Treatment
- Cardiovascular Health and Risk Factors
- Respiratory viral infections research
- Health, Environment, Cognitive Aging
- Food Allergy and Anaphylaxis Research
Rutgers, The State University of New Jersey
2022-2024
All India Institute of Medical Sciences
2024
Christian Medical College & Hospital
2024
Dhanalakshmi Srinivasan Group of Institutions
2024
Vijaya Medical and Educational Trust
2024
Institute for Health Metrics and Evaluation
2024
University of Washington
2024
University of Electronic Science and Technology of China
2023
Rutgers Sexual and Reproductive Health and Rights
2023
Subbaiah Medical College
2021-2022
There is a need for biomarkers to predict outcomes, including mortality, in interstitial lung disease (ILD). Krebs von den Lungen-6 (KL-6) and surfactant protein D (SP-D) are associated with damage fibrosis all ILDs related important clinical outcomes. Though these two have been ILD there no studies that evaluated their predictive potential combination. This study aims determine whether KL-6 SP-D linked poor outcomes mortality. Additionally, we plan examine changes concentrations correspond...
To assess the association between ambient heat and all-cause cause-specific emergency department (ED) visits acute hospitalizations among Medicare beneficiaries in conterminous United States.
To achieve herd immunity to a disease, large portion of the population needs be vaccinated, which is possible only when there broad acceptance vaccine within community. Thus, policymakers need understand how general public will perceive vaccine. This study focused on degree COVID-19 hesitancy and refusal explored sociodemographic correlations that influence refusal. A cross-sectional online survey was conducted among adult India. The consisted basic demographic questions from Vaccination...
Introduction: Coronavirus disease 2019 (COVID-19) pandemic has caused unprecedented mortality and stretched the health infrastructure thin worldwide, especially in low- middle-income countries. There is a need to evaluate easily available biomarkers for their clinical relevance poor outcomes severe cases of COVID-19. It also known that comorbidities affect these with or without We aimed unearth influence on feasible hematological predictive markers hospitalized COVID-19 patients. Materials...
Background Chronic obstructive pulmonary disease (COPD) is no longer considered a exclusive to the respiratory system. It multipronged with both lung and systemic involvement. Although forced expiratory volume (FEV) in one second of most commonly used markers assess severity, recent years, biomarkers such as interleukin-1 beta, serum C-X-C motif chemokine ligand 10, fibrinogen, soluble receptor for advanced glycation, surfactant protein D, club cell secretory have been proven be effective...
Introduction Medication errors (MEs) are a major public health concern as they detrimental to patient safety, compromise patients' confidence in the healthcare system, increase costs, and adversely affect patient's quality of life. This is especially true low middle-income countries where significance MEs largely undervalued. study aims investigate prevalence analyze causes, medicines involved, reporting, severity tertiary care setting. Methods A prospective observational was conducted from...
Acute exacerbations of COPD (AECOPD) are clinically significant events having therapeutic and prognostic consequences. However, there is a lot variation in its clinical manifestations described by phenotypes. The phenotypes AECOPD were categorized this study based on pathology exposure. In our cross-sectional study, conducted between 1 January 2016 to 31 December 2020, the patients into six groups pathology: non-bacterial non-eosinophilic; bacterial; eosinophilic; bacterial infection with...
High-flow nasal cannula (HFNC) and ventilator-delivered non-invasive mechanical ventilation (NIV) were used to treat acute respiratory distress syndrome (ARDS) due COVID-19 pneumonia, especially in low- middle-income countries (LMICs), lack of ventilators manpower resources despite the paucity data regarding their efficacy. This prospective study aimed analyse efficacy HFNC versus NIV management ARDS. A total 88 RT-PCR-confirmed patients with moderate ARDS recruited. Linear regression...
The use of the Ratio Oxygen Saturation (ROX) index to predict success high-flow nasal oxygenation (HFNO) is well established. ROX can also need for intubation, mortality, and easier calculate compared with APACHE II. In this prospective study, primary aim compare (easily administered in resource limited setting) II clinically relevant outcomes such as mortality intubation. Our secondary was identify thresholds predicting length ICU stay failure non-invasive respiratory support therapies...
ADAM33 has been linked to airway structural changes in patients with asthma, leading hyperresponsiveness, narrowing, and ultimately poor treatment responsiveness. This study aimed evaluate the genetic association of SNPs disease severity, responsiveness ICS+LABA South Indian population. In this case-control (486 controls 503 cases), we performed genotyping using MassArray for six ADAM33, namely rs2280091, rs2787094, rs3918396, rs67044, rs2853209, rs3918392. We studied asthma ICS+LABA,...
To evaluate the synergistic effects created by fine particulate matter (PM2.5) and corticosteroid use on hospitalisation mortality in older adults at high risk for cardiovascular thromboembolic events (CTEs). A retrospective cohort study using a US nationwide administrative healthcare claims database. 50% random sample of participants with high-risk conditions CTE from 2008-2016 Medicare Fee-for-Service population. Corticosteroid therapy seasonal-average PM2.5. Incidences myocardial...
Ketone-prone diabetes or Flatbush is being increasingly recognized worldwide. It typically seen in obese middle-aged men with a family history of Type 2 DM. Atypicality the onset age and gender variation observed Predisposition to glucose desensitization one many unclear pathophysiologic mechanisms which why extensive studies are obligatory. After intensive insulin therapy, patients eventually become insulin-independent attain euglycemia oral hypoglycemic agents diet alone due recovered...
Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity and mortality worldwide. However, there lack comprehensive data from low- middle-income countries (LMICs) regarding factors influencing COPD outcomes, particularly in regions where biomass exposure prevalent.
Abstract Background Multiple studies from countries with relatively lower PM 2.5 level demonstrated that acute and chronic exposure even at than recommended level, e.g., 9 μg/m 3 in the US increased risk of cardiovascular (CV) events. However, limited using individual data exist a wider range levels to illustrate shape exposure-response curve throughout including > 20 2·5 concentrations. Taiwan its policies reduced over time provide opportunities dose response curves how reductions...
: Pulmonary tuberculosis (TB) remains a major public health issue in India, with high incidence and mortality. The current literature on post-TB sequelae functional defects focuses heavily spirometry, conflicting obstruction vs. restriction data, lacks advanced statistical analysis, has insufficient data diffusion limitation impairment.
Background The escalating global obesity epidemic requires comprehensive investigations for effective weight management strategies. Understanding the patterns, barriers, and facilitators of dietary interventions is crucial developing protocols. This research aims to assess modification among loss subjects in Tamilnadu, South India. Specific objectives included evaluating various interventions, analyzing patterns adopted by subjects, examining characteristics, associated with specific...
Background: Inhaled corticosteroids (ICS) have an essential and established role in the treatment of asthma. Both systemic local adverse effects may accompany long-term use ICS. Systemic drug reactions (ADRs) ICS are well established. However, there is a pau-city information on ADRs, especially Indian population. Objectives: This study aimed to determine prevalence, severity, predictability, preventabil-ity ADRs their associated risk factors. Methods: Patients with asthma who need were...
Background: There is a paucity of data on biomarkers for the early deterioration and clinical instability patients in community-acquired pneumonia (CAP), as treatment failure occurs first seven days 90% patients. Aim: To evaluate serum albumin copeptin with CURB-65, PSI scoring ATS/IDSA minor criteria prediction mortality or ICU-admission (7 days) after 72 h. Methods: In 100 consecutive hospitalized adult CAP patients, PSI-scores, CURB-65 scores, 2007 criteria, admission were evaluated....
Computer tomography of kidneys, ureters and bladder (CT KUB) is the main investigation in suspected renal tract calculi.Ultrasound (KUB) region can come hand during acute conditions especially patients with ureteric calculus causing hydronephrosis hydroureter.However, several pathologies other than calculi cause apparent urinary calcification.We describe series cases who presented colic.CT KUB performed on admission revealed a calcified urachal remnant mimicking wall calcification, confirmed...