Sinéad Holden

ORCID: 0000-0002-7314-2152
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About
Contact & Profiles
Research Areas
  • Sports injuries and prevention
  • Lower Extremity Biomechanics and Pathologies
  • Knee injuries and reconstruction techniques
  • Occupational Health and Performance
  • Musculoskeletal pain and rehabilitation
  • Pediatric Pain Management Techniques
  • Shoulder Injury and Treatment
  • Foot and Ankle Surgery
  • Child and Adolescent Health
  • Sports Performance and Training
  • Tendon Structure and Treatment
  • Physical Activity and Health
  • Childhood Cancer Survivors' Quality of Life
  • School Health and Nursing Education
  • Total Knee Arthroplasty Outcomes
  • Pain Mechanisms and Treatments
  • Diabetic Foot Ulcer Assessment and Management
  • Children's Physical and Motor Development
  • Cardiovascular Effects of Exercise
  • Obesity, Physical Activity, Diet
  • Osteoarthritis Treatment and Mechanisms
  • Radiology practices and education
  • Ultrasound in Clinical Applications
  • Mental Health and Patient Involvement
  • Exercise and Physiological Responses

Aalborg University
2017-2025

University College Dublin
2013-2025

Institute for Musculoskeletal Health
2020-2022

Government of Western Australia Department of Health
2022

North Denmark Region
2019-2020

Pain Management Institute
2018

Poor reporting of medical and healthcare systematic reviews is a problem from which the sports exercise medicine, musculoskeletal rehabilitation, science fields are not immune. Transparent, accurate comprehensive review helps researchers replicate methods, readers understand what was done why, clinicians policy-makers implement results in practice. The Preferred Reporting Items for Systematic Reviews Meta-Analyses (PRISMA) Statement its accompanying Explanation Elaboration document provide...

10.1136/bjsports-2021-103987 article EN cc-by-nc British Journal of Sports Medicine 2021-10-08

Patellofemoral pain (PFP) is a prevalent lower limb musculo-skeletal injury in adolescent females. Female athletes with PFP display increased frontal plane knee joint motion comparison to control subjects. The current investigation aimed determine prospectively whether two-dimensional valgus displacement during landing could predict the risk of developing PFP. Seventy-six injury-free female (age = 12.9 ±0.35 years) participated. At baseline participants performed three drop vertical jump...

10.1111/sms.12633 article EN Scandinavian Journal of Medicine and Science in Sports 2015-12-29

Investigate the prognosis of adolescent knee pain, and evaluate its impact on health, care-seeking career choices 5 years later.Pre-registered, prospective cohort study.Population-based initiated in school setting.From a 2200 adolescents aged 15-19 2011, 504 reported pain at least monthly basis, were followed prospectively this study, together with 252 controls who did not have 2011.Outcomes included Pain Symptoms subscales from Knee injury Osteoarthritis Outcome Score (KOOS), intensity...

10.1136/bmjopen-2018-024113 article EN cc-by-nc BMJ Open 2019-05-01

To compare pain, physical activity, quality of life, strength, and knee function in adolescents with patellofemoral pain (PFP) Osgood-Schlatter disease (OSD) to those pain-free controls.Cross-sectional study.Self-report questionnaires were used describe function, life participants PFP (n = 151) or OSD 51) controls 50) between 10 14 years age. Hip strength measured by handheld dynamometry. Physical activity levels using wearable accelerometers.Adolescents highly active (accumulating greater...

10.2519/jospt.2020.8770 article EN Journal of Orthopaedic and Sports Physical Therapy 2020-01-06

Patellofemoral pain is a common and often debilitating musculoskeletal condition. Clinical translation evidence synthesis of patellofemoral research are compromised by heterogenous inadequately reported study details. This consensus statement associated checklist provides standards for REPORTing quantitative PatelloFemoral Pain (REPORT-PFP) to enhance clinical synthesis, support clinician engagement with data collection. A three-stage Delphi process was initiated at the 2015 International...

10.1136/bjsports-2020-103700 article EN British Journal of Sports Medicine 2021-06-14

Background: Patellofemoral pain (PFP) affects 7% of adolescents, especially those who are highly active. Exercise-focused treatments show limited effect and overlook activity modification load management. As many adolescents continue at high levels sports despite pain, a new strategy addressing this problem is warranted. Purpose: To investigate the effects treatment for that focuses on Study Design: Cohort study; Level evidence, 2. Methods: Adolescents aged 10 to 14 years with PFP were...

10.1177/0363546519843915 article EN The American Journal of Sports Medicine 2019-05-16

Objective The aim of this study was to examine the association between musculoskeletal (MSK) pain, insomnia, anxiety and depressive symptoms in patients from general practice. Design This is a cross-sectional study. Setting conducted practice Denmark. Participants A consecutive sample 390 (aged 12 years or older) were included; 183 with MSK pain 207 without pain. To be included group, participants required report at least weekly during preceding month, which had negative impact on daily...

10.1136/bmjopen-2019-031971 article EN cc-by-nc BMJ Open 2019-06-01

Abstract Background Osgood–Schlatter disease (OSD) is the most common knee pain complaint among adolescents playing sports. Despite this, there remains controversy over pathophysiology and whether specific anatomical characteristics are associated with OSD. Purpose This study aimed to systematically comprehensively characterize OSD using magnetic resonance imaging (MRI) compared pain‐free controls, including both tissue abnormalities that may be OSD, as well characteristics. A secondary...

10.1111/sms.14634 article EN cc-by-nc-nd Scandinavian Journal of Medicine and Science in Sports 2024-04-29

Osgood Schlatter Disease (OSD) is a common injury in adolescents. A recent systematic review identified multiple tissue characteristics evaluated imaging studies, but the studies used different modalities, varying MRI protocols and were of poor study quality, which led to conflicting findings hamper clinical utility scans. This aimed develop evaluate reliability semi-quantitative scoring system for use adolescents with OSD. Based on review, we an expert-led process list describe soft...

10.1016/j.ejrad.2025.111934 article EN cc-by European Journal of Radiology 2025-01-19

Objectives: Poor sleep is common among young adults and often associated with pain. This study investigates the relationship between pain-related outcomes, quality, quality of life in without knee Methods: a secondary analysis 5-year follow-up prospective cohort study. 523 were surveyed for pain 2011 followed up five years later. Respondents reporting at both points categorized as having (n=177), while controls did not report (n=85). Five-year data assessed clinical intensity, life, physical...

10.1097/ajp.0000000000001283 article EN Clinical Journal of Pain 2025-03-13

Isometric exercise is commonly recommended for immediate pain relief in individuals suffering from lower limb tendinopathies, despite the limited evidence supporting its analgesic effect. Due to similarities between plantar fasciopathy and aim of this trial was investigate acute effect isometric on pain, compared isotonic exercise, or walking, with fasciopathy. We recruited 20 prospectively‐registered, participant‐blinded, randomized, superiority crossover (ClinicalTrials.gov: NCT03264729)....

10.1111/sms.13296 article EN Scandinavian Journal of Medicine and Science in Sports 2018-09-11

Osgood-Schlatter disease (OSD) affects 1 in 10 adolescents. There is a lack of evidence-based interventions, and passive approaches (eg, rest avoidance painful activities) are often prescribed.To investigate an intervention consisting education on activity modification knee-strengthening exercises designed for adolescents with OSD.Case series; Level evidence, 4.This study included 51 (51% female; age range, 10-14 years) OSD. The 12-week consisted ladder to manage patellar tendon loading...

10.1177/2325967120911106 article EN cc-by-nc-nd Orthopaedic Journal of Sports Medicine 2020-04-01

Knee pain is common during adolescence, with Osgood-Schlatter disease (OSD) being the most frequent condition. Despite this, research regarding long-term prognosis of OSD limited.To evaluate 2 to 6 years after diagnosis OSD.Cohort study; Level evidence, 3.This retrospective cohort study included patients diagnosed at a single orthopaedic department between 2010 and 2016. Patients were contacted in 2018 asked complete self-reported questionnaire knee pain, function (Knee injury Osteoarthritis...

10.1177/2325967119878136 article EN cc-by-nc-nd Orthopaedic Journal of Sports Medicine 2019-10-01

Background Osgood Schlatter disease (OSD) is the most common knee condition in adolescent athletes aged 9‐16. Without evidence to guide clinical practice, it unclear how OSD managed. The aim of this study was investigate international healthcare professionals (general practitioners, physiotherapists, rheumatologists, sports and exercise medicine doctors, orthopedic surgeons) diagnose manage OSD. Methods This mixed‐method used a convergent parallel design. A quantitative questionnaire...

10.1111/sms.13751 article EN Scandinavian Journal of Medicine and Science in Sports 2020-06-20

To decide clinical and research priorities on pain features psychological factors in persons with patellofemoral pain.Consensus development process.We undertook a 3-stage process consisting of (1) updating 2 systematic reviews quantitative sensory testing pain, (2) an online survey health care professionals (3) consensus meeting expert professionals. Participants responded that they agreed, disagreed, or were unsure feature factor was important practice as priority. Greater than 70%...

10.2519/jospt.2022.10647 article EN Journal of Orthopaedic and Sports Physical Therapy 2022-01-01

Abstract Patellofemoral pain (PFP) is a common and recurrent knee condition in young females, characterized by pressure hyperalgesia reduced inhibitory control. This study investigated antinociceptive pronociceptive profiles females with long-standing (>5 years) PFP (current-PFP), those who recovered from adolescent (recovered-PFP), pain-free controls. preregistered, assessor-blinded, cross-sectional included 87 younger than 25 years: 36 current-PFP, 22 recovered-PFP, 29 The primary...

10.1097/j.pain.0000000000001356 article EN Pain 2018-08-01
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