A5091878235- Ethnobotanical and Medicinal Plants Studies
- Essential Oils and Antimicrobial Activity
- Phytochemicals and Antioxidant Activities
- Computational Drug Discovery Methods
- Natural Antidiabetic Agents Studies
- Phytochemistry and Biological Activities
- Natural product bioactivities and synthesis
- Pharmacological Effects of Natural Compounds
- Medicinal Plants and Neuroprotection
- Drug-Induced Hepatotoxicity and Protection
- Rheumatoid Arthritis Research and Therapies
- Morinda citrifolia extract uses
- Moringa oleifera research and applications
- Pharmacological Effects of Medicinal Plants
- Botanical Research and Applications
- Nanoparticle-Based Drug Delivery
- Pharmacological Effects and Assays
- Cancer Research and Treatment
- Spectroscopy and Chemometric Analyses
- Cholinesterase and Neurodegenerative Diseases
- Analytical Chemistry and Sensors
- Genomics, phytochemicals, and oxidative stress
- Medicinal Plant Research
- Phytochemical compounds biological activities
- Hibiscus Plant Research Studies
Dayananda Sagar University
2021-2024
Dr. Hari Singh Gour University
2021-2024
Maternal Embryonic Leucine Zipper Kinase (MELK), a pivotal signaling protein, plays crucial role in various physiological processes such as cell growth, survival, and differentiation. There is currently growing interest MELK promising therapeutic target for multiple cancers, including triple‐negative breast cancer (TNBC). Exploring offers prospective strategy to impede progression enhance the efficacy of conventional anticancer therapies. In this study, we employed multistep docking...
The present study was undertaken to investigate the protective effect and possible mechanism of methanolic extract Barleria montana (BM) on ethanol-induced rat hepatic injury. This respective activity assessed through monitoring liver function tests measurement triglycerides, cholesterol, total protein, bilirubin, serum enzymes like SGOT SGPT in vivo antioxidant parameters lipid peroxidase, Superoxide dismutase(SOD) catalase,. Further, tissues were also subjected histopathological studies....
Introduction: Gauzuma ulmifolia Lam. (GU) belonging to the family Malvaceae, commonly called Bastard Cedar is native tropical American countries. It was introduced into India more than 100 years ago. Methods: In present study, alcoholic seed extract of subjected GC MS/MS analysis and chemical compounds were characterized. Results: Totally sixteen Chemical showed that it includes bioactive like D-Asarinin (65.02 %), 2,6-Bis (3,4-methylenedioxyphenyl)-3,7-dioxabicyclo (3.3.0) octane (20.12...
Rheumatoid Arthritis (RA) is a persistent inflammatory autoimmune illness that damages bones by causing joint discomfort, edema, and stiffness. In RA, cell infiltration synovial hyperplasia lead to the generation of proinflammatory cytokines like TNF-α IL-1. To find phytochemical substances utilised in RA treatment, SciELO, Virtual Health Library, PubMed databases were searched for rheumatoid arthritis, herbal remedies, medicinal plants. One predominant transcription factors NF-κB,...
Introduction: Indigenous plants are plant species that native to a specific region and have evolved naturally adapted local environmental conditions over long period. Aim: This study aimed explore the anti-arthritic effects of Atylosia goensis, an indigenous in Western Ghats India. Methodology: An ethanolic extract goensis was obtained using Soxhlet extraction method, which revealed diverse array phytochemicals through liquid chromatography-mass spectroscopy (LC-MS). Key compounds, including...
Abstract Alzheimer’s disease (AD) is a neuron degenerative disorder. The MAO enzymes are potential therapeutic targets for the treatment of neurological illnesses because their crucial role in breakdown neurotransmitters that results formation some hazardous compounds. Because inhibition reduces oxidative stress brought on enzymes, it has significant anti-Alzheimer impact. Consequently, purpose this investigation was to find out potent natural compounds could be used as medication treat AD...
The present investigation was carried out to study the histological characters of roots plant Barleria cristata Linn. Further phytochemical studies on methanolic extract revealed presence alkaloids. Column chromatography (MEBC) by using silica gel (60–120#) column chromatography. It eluted different solvents in their increasing order polarity. Fraction No.11 purified fractional crystallization yield 55mg brown coloured amorphous powder Compound-I which characterized and confirmed as...
Protein kinases play a prominent role in transferring phosphate group from ATP (adenosine triphosphate) to serine, tyrosine, or threonine residues.Mutation and dysregulation their activity lead an imbalance the health causing diseases like cancer.Protein kinase inhibitors have proved be more effective addressing such impairment caused by of protein kinases.Several antibodies small molecules been approved regulatory bodies US FDA, many them are being developed expected enter clinical trials...
Plant-based medicine gained importance due to its safety margin and multiple benefits.Regular intake of antioxidants is an alternative avoid serious illness.The current investigation aims measure the phenolic, flavonoid content, antioxidant activity Atylosia goensis Dalzell, antiinflammatory profile.Total phenolic content was estimated by standard colorimetric assays screened using DPPH Nitric Oxide free radical scavenging assay.The extracts were for In vitro COX enzyme inhibition assay with...