Md. Al Amin

ORCID: 0000-0003-2428-9657
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About
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Research Areas
  • Computational Drug Discovery Methods
  • Synthesis and biological activity
  • Genomics, phytochemicals, and oxidative stress
  • Bioactive Compounds and Antitumor Agents
  • Nutrition, Genetics, and Disease
  • Fractional Differential Equations Solutions
  • Medicinal Plants and Neuroprotection
  • Phytoestrogen effects and research
  • Phytochemicals and Antioxidant Activities
  • Gene expression and cancer classification
  • Alzheimer's disease research and treatments
  • Cancer therapeutics and mechanisms
  • Berberine and alkaloids research
  • Advanced biosensing and bioanalysis techniques
  • Machine Learning in Healthcare
  • Estrogen and related hormone effects
  • Ovarian function and disorders
  • Allelopathy and phytotoxic interactions
  • Food Safety and Hygiene
  • Ferrocene Chemistry and Applications
  • Advanced Control Systems Design
  • Innovative Teaching Methods
  • Escherichia coli research studies
  • Helicobacter pylori-related gastroenterology studies
  • Sepsis Diagnosis and Treatment

Mawlana Bhashani Science and Technology University
2021-2025

Daffodil International University
2020-2025

University of Rajshahi
2024

Trine University
2024

American University
2024

Kent State University
2024

Prime University
2023

Stamford University Bangladesh
2019

University of Chittagong
2017

Breast cancer (BC) is one of the most common malignancies in women. Although widespread successful synthetic drugs are available, natural compounds can also be considered as significant anticancer agents for treating BC. Some have similar effects with fewer side on normal cells. Therefore, we aimed to unravel and analyze several molecular mechanisms genistein (GNT) against GNT a type dietary phytoestrogen included flavonoid group structure estrogen that might provide strong alternative...

10.3390/pr10020415 article EN Processes 2022-02-21

Maternal Embryonic Leucine Zipper Kinase (MELK), a pivotal signaling protein, plays crucial role in various physiological processes such as cell growth, survival, and differentiation. There is currently growing interest MELK promising therapeutic target for multiple cancers, including triple‐negative breast cancer (TNBC). Exploring offers prospective strategy to impede progression enhance the efficacy of conventional anticancer therapies. In this study, we employed multistep docking...

10.1002/cbdv.202402864 article EN Chemistry & Biodiversity 2025-01-27

As many devices connect to the internet and people save more information on cloud increase their usage of digital communication, threat level sphere has increased significantly. With device connectivity use money transactions cyber threats have become sophisticated than ever. Conventional discrete security policies are ineffective address behavioral constantly changing nature today’s cybersecurity such as zero-day exploits, APTs or ransomware. In this light, AI ML considered strategic...

10.5121/ijcsit.2025.17101 article EN International Journal of Computer Science and Information Technology 2025-02-27

Neurodegenerative diseases (NDs) exhibit significant global public health challenges due to the lack of effective treatments. Berberine (BBR), a natural alkaloid compound in various plants, has been recognized for its potential neuroprotective properties. This review explores current understanding BBR's mechanisms action and therapeutic preventing treating NDs such as Alzheimer's disease, Parkinson's Huntington's disease. properties are attributed multifaceted actions, including...

10.1002/cbdv.202500170 article EN Chemistry & Biodiversity 2025-03-24

Breast cancer, a leading cause of female mortality, is closely linked to mutations in estrogen receptor beta (ESR2), particularly the ligand-binding domain, which contributed altered signaling pathways and uncontrolled cell growth.

10.1002/cam4.70074 article EN cc-by Cancer Medicine 2024-08-01

Despite modern treatment, infertility remains one of the most common gynecologic diseases causing severe health effects worldwide. The clinical and epidemiological data have shown that several cancerous risk factors are strongly linked to Female Infertility (FI) development, but exact causes remain unknown. Understanding how these affect FI-affected cell pathways might pave door for discovery critical signaling hub proteins may be targeted therapeutic intervention. To deal with this, we used...

10.1371/journal.pone.0265746 article EN cc-by PLoS ONE 2023-01-06

Shigella stands as a major contributor to bacterial dysentery worldwide scale, particularly in developing countries with inadequate sanitation and hygiene. The emergence of multidrug-resistant strains exacerbates the challenge treating infections, regions where access healthcare alternative antibiotics is limited. Therefore, investigations on how bacteria evade eventually develop resistance could open new avenues for research novel therapeutics. aim this study was analyze whole genome...

10.1155/2024/5554208 article EN BioMed Research International 2024-03-21

This study retrieves some novel exact solutions to the family of 3D space-time fractional Wazwaz-Benjamin-Bona-Mahony (WBBM) equations in context diverse nonlinear physical phenomena resulting from water wave mechanics. The WBBM is transformed for this purpose using a space and time transformation into an ordinary differential equation (ODE). ODE then uses strong method, namely Unified Method. Consequently, lump solutions, dark-bright soliton, singular multiple soliton periodic are...

10.1038/s41598-024-61405-8 article EN cc-by Scientific Reports 2024-07-16

This article delves into the dynamic constructions of distinctive traveling wave solutions for circulation in shallow water mechanics, specifically addressing time-fractional couple Drinfel'd–Sokolov–Wilson (DSW) equation. Introducing previously untapped $$exp(-\phi (\xi ))$$ -expansion method, we successfully generate a diverse set analytic expressed hyperbolic, trigonometric, and rational functions, each with permitted parameters. Visualization through three-dimensional (3D) as well...

10.1038/s41598-024-64348-2 article EN cc-by-nc-nd Scientific Reports 2024-08-14

Abstract Background Helicobacter pylori is a gastric pathogen that responsible for causing chronic inflammation and increasing the risk of cancer development. It capable persisting decades in harsh environment because inability host to eradicate infection. Several treatment strategies have been developed against this bacterium using different antibiotics. But effectiveness treating H. has significantly decreased due widespread antibiotic resistance, including an increased cancer. The small...

10.1002/cam4.6772 article EN cc-by Cancer Medicine 2023-12-01

Female infertility may be caused by several medical conditions and environmental factors that induce fallopian tube damage or hormonal difficulties. Several metabolic comorbidities like polycystic ovarian syndrome (PCOS), type 2 diabetes (T2D), obesity, cardiovascular disease (CVD) have been associated with female (FI). However, the causal connection molecular features are still unknown. Here, we used differentially expressed genes (DEGs) to uncover various biological targets for a better...

10.1016/j.imu.2022.100960 article EN cc-by-nc-nd Informatics in Medicine Unlocked 2022-01-01

Mycoplasma genitalium is a pathogenic microorganism linked to variety of severe health conditions including ovarian cancer, prostate HIV transmission, and sexually transmitted diseases. A more effective approach address the challenges posed by this pathogen, given its high antibiotic resistance rates, could be development peptide vaccine. In study, we used experimentally validated 13 membrane proteins their immunogenicity identify suitable vaccine candidates. Thus, based on immunogenic...

10.1016/j.heliyon.2024.e28223 article EN cc-by-nc Heliyon 2024-03-28

Bangladesh is aspiring to develop a competitive workforce for the 21stcentury. To reach this aspiration, STEM education can be good way as it has widely been considered have potential prepare students with 21st-century skills. The potentiality of fully utilized only when teachers apply approaches effectively in their practices. Since teachers’ prior views and perceptions fluence teaching, study aims explore theteachers ’ perception education. This also analyzes challenges introducing at...

10.34257/gjhssgvol23is8pg39 article EN Global Journal of Human-Social Science 2023-08-25

Despite the significant progress in cancer genomics America, there is still a noteworthy gap regarding genomic markers that predict drug sensitivity which presents major obstacle to personalized oncology care. Tumors This research project aims identify set of genetic variations or mutations influence individual response patient certain drugs. study also develop machine learning models can analyze patient's data their likely different therapies. utilized Genomic Drug Sensitivity Cancer...

10.37547/tajmspr/volume06issue12-06 article EN The American Journal of Medical Sciences and Pharmaceutical Research 2024-12-11
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