A5038125782- Palliative Care and End-of-Life Issues
- Cancer survivorship and care
- Childhood Cancer Survivors' Quality of Life
- Interprofessional Education and Collaboration
- Genetic factors in colorectal cancer
- Cancer Genomics and Diagnostics
- Evaluation and Performance Assessment
- Pain Management and Opioid Use
- Neuroendocrine Tumor Research Advances
- Lung Cancer Research Studies
- Clinical practice guidelines implementation
- Neuroblastoma Research and Treatments
- Colorectal Cancer Screening and Detection
- Patient-Provider Communication in Healthcare
University of Pittsburgh Medical Center
2022
University of Pittsburgh
2021
Icahn School of Medicine at Mount Sinai
2018-2020
Mount Sinai Hospital
2018
Providence Regional Medical Center Everett
2018
Objective Given the lack of consensus on surveillance guidelines after pancreatic neuroendocrine tumor (PanNET) resection, we assessed outcomes in a large cohort patients with nonmetastatic, surgically resected PanNETs. Methods Data PanNETs between 1990 and 2017 were retrospectively collected using databases at 3 academic institutions. The National Death Index was queried to determine vital status. Kaplan-Meier analysis used estimate recurrence-free survival (RFS) disease-specific (DSS)...
PURPOSE Limited data are available on the prevalence and clinical impact of Lynch syndrome (LS)–associated genomic variants in non-European ancestry populations. We identified characterized individuals harboring LS-associated ancestrally diverse Bio Me Biobank New York City. PATIENTS AND METHODS Exome sequence from 30,223 adult participants were evaluated for pathogenic, likely predicted loss-of-function MLH1, MSH2, MSH6, PMS2. Survey electronic health record variant-positive reviewed...
Purpose: The Quality Oncology Practice Initiative (QOPI) is a quality measurement and improvement program designed to assess practice performance for various consensus-based evidence-based measures. In this study, we evaluated differences in QOPI metrics met among patients with advanced solid cancer receiving routine oncologic care alone (routine care) compared integrated oncology specialty-level palliative (supportive care). Methods: We conducted retrospective chart review of 100 randomly...
Older patients with acute leukemia (AL) have a high symptom burden and poor prognosis. Although integration of palliative care (PC) oncologic has been shown to improve quality-of-life end-of-life in AL, the malignant hematologists at our tertiary hospital make limited use PC services do so late disease course. Using Plan-Do-Study-Act (PDSA) methodology, we aimed increase early utilization by older newly diagnosed AL.We instituted following standardized criteria trigger inpatient...
Despite guidelines, chemotherapy near end-of-life (EOL) remains common, particularly in hematologic malignancy (HM). Determinants of EOL for hospitalized cancer patients are not well elucidated. We performed a retrospective cross-sectional descriptive study who died inpatient within two weeks 2012 and 2014. By chart review, we identified patient characteristics, estimated performance status, categorized cause death, abstracted clinical intent. 102 patients; 65% with HM 35% SM. Amongst these...
1520 Background: Lynch syndrome (LS), caused by germline pathogenic variants in mismatch repair (MMR) genes, results increased risk of colorectal, endometrial, and other cancers. LS has a prevalence ~1 440 European ancestry populations; data populations are limited. We identified characterized carriers MMR gene the multi-ethnic Bio Me Biobank New York City. Methods: Exome sequence from ~31,000 participants were evaluated for known (per ClinVar) predicted (loss-of-function) genes. Population...
12105 Background: Prior studies have shown that integration of early outpatient specialty palliative care (OSPC) with oncologic improves patient’s symptom burden and quality life. As a result, the American Society Clinical Oncology (ASCO) recommends OSPC be offered within 8 weeks diagnosis an advanced solid malignancy. Over past decade, there has been increase in availability services, particularly at National Cancer Institute (NCI)-designated cancer centers; however, majority referrals...