A5044437675- Fungal Biology and Applications
- Polysaccharides and Plant Cell Walls
- Food Quality and Safety Studies
- Seismic Imaging and Inversion Techniques
- Seismic Waves and Analysis
- Seismology and Earthquake Studies
- Chemical synthesis and alkaloids
- earthquake and tectonic studies
- Seaweed-derived Bioactive Compounds
- Botanical Research and Chemistry
- Radioactive element chemistry and processing
- Tea Polyphenols and Effects
- Plant Pathogens and Fungal Diseases
- Plant Physiology and Cultivation Studies
- Groundwater flow and contamination studies
- Groundwater and Isotope Geochemistry
- Polysaccharides Composition and Applications
- Advanced NMR Techniques and Applications
- Phytoestrogen effects and research
- Phytochemistry and Bioactivity Studies
- Mycorrhizal Fungi and Plant Interactions
- Phytochemicals and Antioxidant Activities
- Enzyme Production and Characterization
- Fermentation and Sensory Analysis
- Garlic and Onion Studies
Hokkaido University
1990-2025
Towada City Hospital
2020-2024
Konica Minolta (Japan)
2018-2024
Houston Methodist Sugar Land Hospital
2024
Japan Atomic Energy Agency
2009-2023
Nagoya University
2023
Schlumberger (British Virgin Islands)
2008-2022
Saitama University
1993-2021
Schlumberger (United States)
2019-2021
Gifu University
1951-2019
It has been known for many years that most mushrooms with effects against cancer belong to the family Polyporaceae s.l. (Agaricales s.l.). However, components responsible such action have not clearly defined. In Japan, in 1968, a hot water extract from some edible belonging s.l., showed marked host-mediated antitumor activity. Since then, numerous researchers isolated active polysaccharides and identified them be (1→3)-β-D-glucopyranans (1→6)-β-D-glucosyl branch containing protein. Several...
In the course of our screening work for new types lipase inhibitors, hesperidin was identified as a simple and small molecular weight inhibitor in peels Citrus unshiu. Hesperidin inhibited activity from porcine pancreas that Pseudomonas, their IC50 32 132 μg/ml, respectively. Hesperidin, neohesperidin, narirutin, naringin are known main flavonoids Neohesperidin also procine pancreas, but did not have any effect on Pseudomonas. Narirutin show this lipases animal experiments, concentration...
Abstract It has been known for many years that most fungi which have effects against cancers of the stomach, esophagus, lungs, etc., belong to Polyporacea. However, components responsible such action not clearly defined. In Japan, in 1968, it was reported a hot water extract from some edible mushrooms belonging Polyporacea showed marked host‐mediated antitumor activity. Since then, numerous researchers isolated active materials and identified them be (1—3)‐ß‐D‐glucopyranans with...
Journal Article Antitumor Active Fucoidan from the Brown Seaweed, Umitoranoo (Sargassum thunbergii) Get access Cun Zhuang, Zhuang United Graduate School of Agricultural Sciences, Gifu University (Shizuoka University), 1–1 Yanagido, 501–11, Japan Search for other works by this author on: Oxford Academic Google Scholar Hiroko Itoh, Itoh JapanLaboratory Marine Biochemistry, Faculty Bioresources, Mie University, Tsu, 514, Takashi Mizuno, Mizuno JapanDepartment Applied Biological Chemistry,...
Journal Article Antitumor Activity and Some Properties of Water-soluble Polysaccharides from “Himematsutake,” the Fruiting Body Agavicus blazei Murill Get access Takashi Mizuno, Mizuno Faculty Agriculture, Shizuoka University, Ohya, 422, Japan Search for other works by this author on: Oxford Academic Google Scholar Toshihiko Hagiwara, Hagiwara Nichirei Research Institute, Higashi-murayama, Tokyo 189, Takuji Nakamura, Nakamura Hitoshi Ito, Ito School Medicine, Mie Tsu, 514, Keishiro Shimura,...
(1995). Reishi, Ganoderma lucidum and tsugae: Bioactive substances medicinal effects. Food Reviews International: Vol. 11, Mushrooms: The Versatile Fungus-Food Medicinal Properties, pp. 151-166.
Journal Article Antitumor-active Polysaccharides Isolated from the Fruiting Body of Hericium erinaceum, an Edible and Medicinal Mushroom Called yamabushitake or houtou Get access Takashi Mizuno, Mizuno Faculty Agriculture, Shizuoka University, Ohya, 422, Japan Search for other works by this author on: Oxford Academic Google Scholar Tetsuya Wasa, Wasa Hitoshi Ito, Ito JapanSchool Medicine, Mie Tsu, 514, Chiharu Suzuki, Suzuki JapanFuji Biocenter, Fuji Seito Co., Ltd., Shibakawa-cho, 419–03,...
Abstract Out of the several thousand species mushrooms (Basidiomycetes and Ascomycetes) on earth, 1500 are found in Japan. Many these valuable as gene pool sources which can be utilized by biotechnology to develop new foods medicines. edible now being studied for their nutritional flavor properties. To utilize full potential mushrooms, it is necessary consider toxicity poisonous ones also improve food sanitation practices associated with cultivation, processing, preservation, storage mushrooms.
The accurate crystal structure of nicotinamide, 3-pyridinecarboxamide, was determined from X-ray and neutron diffraction experiments: C(6)H(6)N(2)O, M(r) = 122.13, monoclinic, P2(1)/c, Z 4. electron distribution at 150 K by the maximum entropy method electrostatic potential in calculated Fourier convolution distribution. properties nicotinamide molecule depend on molecular conformation. asymmetric field observed above below pyridine-ring plane is related to rotation carboxamide group with...
Polysaccharides extracted from Himematsutake, the fruiting body of Agaricus blazei Murill with hot water were fractionated and purified by ethanol precipitation, ion-exchange chromatography, gel-filtration, affinity etc. A total 17 polysaccharide samples thus obtained given an antitumor activity test (Sarcoma 180/mice i.p. p.o. method) traces their activities through fractionation purification processes found. FI0-a-β, FA-1-a-α, FA-1-a-β, FA-2-b-β, as soluble polysaccharides fractions having...
Journal Article Antitumor Active Polysaccharides from the Chinese Mushroom Songshan Lingzhi, Fruiting Body of Ganoderma tsugae Get access Guanying Wang, Wang Department Traditional Pharmacy, Changchun College Medicine, Changchun, Jilin, China Search for other works by this author on: Oxford Academic Google Scholar Jie Zhang, Zhang Takashi Mizuno, Mizuno ChinaFaculty Agriculture, Shizuoka University, Ohya, 422, Japan To whom all correspondence should be addressed. Cun Zhuang, Zhuang Hitoshi...
A probably new entity of metabolic error folic acid was described an infant whose clinical and biochemical characteristics were: 1) mental retarda-tion a marked dilatation cerebral ventricles, 2) abnormally high serum L. casei folate activity, 3) levels precursor in erythrocytes, 4) rise reticulocyte count by exogenous supplementation. The results investigation on tetrahydrofolate-dependent enzymes liver specimens revealed decreased activity N5 methyltetrahydrofolate transferase our own...
Protein-containing polysaccharides from Inonotus obliquus (Chaga), sclerotia and mycelia were extracted partially purified. They examined as potential inhibitors of the cell cycle regulatory enzymes cdc25 cdc2/cyclin B for their hypoglycemic effect, following results obtained. The enzyme inhibitory activity effects in normal mice detected both water-soluble water-insoluble polysaccharides. active principles β-glucan, heteroglucan, protein complexes. No clear antienzymic traits recognized by...