- Sports Dynamics and Biomechanics
- Shoulder Injury and Treatment
- Catalytic C–H Functionalization Methods
- Fungal Biology and Applications
- Synthesis and Catalytic Reactions
- Asymmetric Hydrogenation and Catalysis
- Neurosurgical Procedures and Complications
- Polysaccharides and Plant Cell Walls
- Stress Responses and Cortisol
- Cerebrovascular and genetic disorders
- Glycosylation and Glycoproteins Research
- Intracerebral and Subarachnoid Hemorrhage Research
- Mycorrhizal Fungi and Plant Interactions
- Cancer Treatment and Pharmacology
- Sports Performance and Training
- Catalytic Cross-Coupling Reactions
- Connective tissue disorders research
- Pain Management and Placebo Effect
- Intracranial Aneurysms: Treatment and Complications
- S100 Proteins and Annexins
- Pain Management and Opioid Use
- Tryptophan and brain disorders
- Food Quality and Safety Studies
- Healthcare professionals’ stress and burnout
- Proteoglycans and glycosaminoglycans research
Nagoya University
2025
Aichi Medical University
2010-2024
Meijo University
2022-2024
Systems Biology Institute
2024
National Institute for Fusion Science
2024
Neurological Surgery
2023
Chiba University
2023
Gunma University
2022
St. Luke's International University
2021
St. Luke's International Hospital
2021
The iridium-catalyzed dehydrogenative cyclization of 2-aminobiphenyls proceeds smoothly in the presence a copper cocatalyst under air as terminal oxidant through intramolecular direct C–H amination to produce N-H carbazoles. A similar iridium/copper system can also catalyze unprecedented dimerization reaction 2-aminobiphenyl involving 2-fold C–H/N–H couplings.
Journal Article Antitumor-active Polysaccharides Isolated from the Fruiting Body of Hericium erinaceum, an Edible and Medicinal Mushroom Called yamabushitake or houtou Get access Takashi Mizuno, Mizuno Faculty Agriculture, Shizuoka University, Ohya, 422, Japan Search for other works by this author on: Oxford Academic Google Scholar Tetsuya Wasa, Wasa Hitoshi Ito, Ito JapanSchool Medicine, Mie Tsu, 514, Chiharu Suzuki, Suzuki JapanFuji Biocenter, Fuji Seito Co., Ltd., Shibakawa-cho, 419–03,...
The ruthenium-catalyzed alkenylation reactions of 2-aminobiphenyls and cumylamine proceed smoothly to produce the corresponding regioselectively alkenylated products. These involve a C-H bond cleavage directed by their free amino groups.
Abstract The dehydrogenative direct coupling of α,α‐disubstituted benzylamines with acrylates takes place efficiently at room temperature under ruthenium catalysis, accompanied by free amino group‐directed ortho ‐alkenylation and successive cyclization to produce (isoindol‐1‐yl)acetic acid derivatives. reactions using styrenes in proceed effectively the presence a rhodium catalyst rather than ruthenium. magnified image
To determine the prevalence of burnout according to job category after first wave COVID-19 in Japan and explore its association with certain factors.An online cross-sectional survey health care workers (HCWs) from June 15 July 6, 2020, was conducted at a tertiary hospital Tokyo, Japan. Demographic characteristics, results Japanese version Maslach Burnout Inventory-General Survey, types anxiety stress, changes life work peak pandemic, support aimed reducing physical or mental burden, were...
Protein-containing polysaccharides extracted from fruiting bodies of a Chinese fungus named Feng Wei Gu, were fractionated and purified, their antitumor activities tested, out which the following active fractions obtained. FIo-a: A protein-containing xyloglucan, MW 280,000, polysaccharide: protein = 76:24 (w/w), polysaccharide consisting Man:Gal:Xyl:Glc 2:12:42:42 (molar ratio). [alpha]D23 + 25.3 degrees. FA-2: mannogalactan, 120,000, 76:16 Xyl:Man:Gal 9:35:56 ratio), 98.5 FII-1: xylan...
A water-soluble polysaccharide, FI, and water-insoluble polysaccharides, FII FIII were extracted from Pleurotus citrinopileatus mushrooms. After fractionation, the antitumor activity of fractions against Sarcoma 180 implanted in mice examined, following active polysaccharides obtained: Water-soluble FIO: heteropolysaccharide containing 9.8% protein, composed glucose, mannose, arabinose, galactose. FA-2-b-β: glycoprotein consisting glycan: protein = 40:60 w/w, with glyco-chain xylose,...
Spinal cord injury (SCI) induces devastating permanent deficits. Recently, cell transplantation therapy has become a notable treatment for SCI. Although stem cells from human exfoliated deciduous teeth (SHED) are an attractive therapy, their precise mechanism of action remains to be elucidated. In this study, we explored one the neuroprotective mechanisms SHED at subacute stage after We used rat clip compression SCI model. The animals were randomly divided into three groups: SCI, +...
Anaerobic soil disinfestation (ASD) consists of the application labile organic materials to soil, flooding, and covering surface with plastic film. is a widely used ecofriendly alternative chemical fumigation for eliminating soil-borne plant pathogens. However, exact mode action ASD has not been elucidated. In particular, potential role anaerobic bacteria in unclear. this study, we isolated predominant bacterium designated as strain E801 from cocopeat medium after laboratory-scale ethanol...
Metastatic bone pain is characteristic of cancer and a form refractory pain, as the includes not only nociceptive but also neuropathic pain. Although some drugs are effective in management painful metastases, while moving one most forms pulsed radiofrequency (RF) dramatically reduces chronic vertebral metastatic number cases reported these studies was very small (five or less).Case report.Single center.Fifteen patients suffering from intractable pain.Dorsal root ganglion (DRG) RF.A numerical...
During the life cycle of flowering plants, nuclear fusion, or karyogamy, occurs three times: once during female gametogenesis, when two polar nuclei fuse in central cell, and twice double fertilization. In Arabidopsis thaliana, fusion events sexual reproduction proceed without breakdown envelope, indicating that membrane is essential for completion this process. gamete expressed 1 (GEX1) a protein conserved among plant species. GEX1 shares homology with yeast karyogamy Kar5, which primarily...
The high-pressure gas (HPG) method with carbon monoxide (CO) and oxygen (O2) mixture maintains the preserved rat heart function. metabolites of hearts using HPG (HPG group) cold storage (CS) (CS by immersion in a stock solution for 24 h were assessed to confirm CO O2 effects. Lactic acid was significantly lower citric higher group than CS group. Moreover, adenosine triphosphate (ATP) levels as well some pentose phosphate pathway (PPP) reduced nicotinamide adenine dinucleotide (NADPH)...
A chronic subdural hematoma (CSDH) is considered to be an inflammatory and angiogenic disease. The CSDH outer membrane, which contains cells, plays important role in development. Osteopontin (OPN) extracellular matrix protein that cleaved by thrombin, generating the N-terminal half of OPN, prominently involved integrin signal transduction. We explored expression OPN fluid integrins α9 β1 downstream components signaling pathways membrane CSDHs.Twenty samples eight were collected from patients...
The purpose of this study was to clarify the relationship between ball velocity and mechanical power lower limbs during pitching motion in 30 collegiate baseball pitchers. 3-dimensional positions 37 reflective markers attached subject were tracked by an optical capture system (Mac3D System) with 12 cameras. ground-reaction forces (GRF) pivot stride legs determined using 2 multicomponent force plates. Pitching assessed terms joint torques, torque powers work done each a three-dimensional...
The purpose of this study was to clarify the profiles lower limb and trunk motion during baseball pitching in relation differences between mound flat ground, determine characteristics while from 2 locations. subjects were 12 pitchers (age 18.6±2.5 yr, height 173.4±6.5 cm, weight 74.7±11.0 kg) who belonged high school or university teams. Three-dimensional positions 36 reflective markers attached each subject tracked by an optical capture system (Mac3D System) with cameras. ground-reaction...