A5005233195- Olfactory and Sensory Function Studies
- Anesthesia and Sedative Agents
- Neuroendocrine regulation and behavior
- Neuropeptides and Animal Physiology
- Retinal Development and Disorders
- Stress Responses and Cortisol
- Receptor Mechanisms and Signaling
- Animal Ecology and Behavior Studies
- Anesthesia and Pain Management
- Metabolism and Genetic Disorders
- Insect and Pesticide Research
- Fluid Dynamics and Vibration Analysis
- Neuroscience and Neuropharmacology Research
- Virus-based gene therapy research
- Cardiac, Anesthesia and Surgical Outcomes
- Biochemical Analysis and Sensing Techniques
- Biochemical effects in animals
- Neurobiology and Insect Physiology Research
- Neurobiology of Language and Bilingualism
- Veterinary Medicine and Surgery
- Structural Engineering and Vibration Analysis
- Neuroscience of respiration and sleep
- Mast cells and histamine
- Glycosylation and Glycoproteins Research
- Animal health and immunology
Iwate University
2014-2024
National Institute of Mental Health
2018
Osaka University
1960-2013
keiyu Hospital
2007-2012
Neuroscience Institute
2012
Tokai University
2008-2011
Kyushu University
2000-2010
Yamaguchi Red Cross Hospital
1991-2010
AgroBio
2010
Osaka Medical and Pharmaceutical University
2010
Vascular endothelial growth factor-C (VEGF-C) functions specifically to induce lymphangiogenesis. We examined the relationship between expression of VEGF-C and clinicopathological features in patients with colorectal cancer. The 99 primary tumours 18 metastatic lymph nodes from cancer was immunohistochemically. To verify mRNA expression, reverse transcriptase-polymerase chain reaction (RT-PCR) carried out. correlated lymphatic involvement, metastasis, depth invasion. On other hand,...
The C-4 hydroxylation of sphinganine and dihydroceramide is a rate-limiting reaction in the biosynthesis phytosphingolipids. Mouse DES1 (MDES1) cDNA homologous to Drosophila melanogaster degenerative spermatocyte gene-1 (des-1) leads sphingosine Delta4-desaturase activity, another mouse homologue, MDES2, has bifunctional producing hydroxysphinganine Delta4-sphingenine yeast [Ternes, Franke, Zahringer, Sperling Heinz (2002) J. Biol. Chem. 277, 25512-25518]. Here, we report characterization...
Helically cut strips of dog renal and cerebral (basilar middle cerebral) arteries contracted with prostaglandin (PG) F2 alpha relaxed in response to angiotensin II (AII; 10(-9) 10(-7) M) a dose-dependent manner. In arterial strips, the relaxation was preceded by transient contraction. Both contraction induced AII were suppressed [Sar1,Ala8]AII or [Sar1,Ile8]AII. Treatment propranolol, atropine, hexamethonium, cocaine, aminophylline, cimetidine, ouabain failed alter relaxing effect AII. The...
Cats anoint themselves with plant metabolites that confer mosquito repellence.
Summary Fruit malformation is a major constrain in fruit production worldwide resulting substantial economic losses. The farmers for decades noticed that the chilling temperature before blooming often caused malformed fruits. However, molecular mechanism underlying this phenomenon unclear. Here we examined development response to cold stress tomato, and demonstrated short‐term increased callose accumulation both shoot apical floral meristems, symplastic isolation altered intercellular...
Normal mammals generally excrete only small amounts of protein in the urine, thus avoiding major leakage proteins from body. Proteinuria is most commonly recognized abnormality renal disease. However, healthy domestic cats ( Felis catus ) at high concentrations (about 0.5 mg/ml) their urine. We investigated possible cause proteinuria cats, and discovered a 70 kDa glycoprotein, which was excreted as urinary cat irrespective gender. To elucidate biochemical functions excretion mechanism this...
Scent emitted from anal sac secretions provides important signals for most Carnivora. Their emit a variety of volatile compounds, some which function as chemical with information about the scent owners. The domestic cat has pair glands to secrete pungent liquid. may give sex, reproductive state, and recognition individuals. However, little is known compounds their biological functions in cats. In this study, we examined profiles cats olfactory ability discriminate intraspecific secretions....
We isolated the Cobetia sp. strains IU 180733JP01 (5-11-6-3) and 190790JP01 (5-25-4-2) from seaweeds, showed that both accumulate poly(3-hydroxybutyrate) [P(3HB)] homopolymer in a nitrogen-limiting mineral salt medium containing alginate as sole carbon source. Genome sequence analysis of they have putative genes which encode enzymes relevant to assimilation P(3HB) synthesis, alginate-assimilating formed cluster. Investigation optimum culture conditions for high accumulation when 5-11-6-3...
AimAdrenomedullin (ADM) has been shown to protect the heart against ischaemic injury, but little is known of underlying mechanism. Mitochondrial Ca2+-activated K+ (mitoKCa) channels play a key role in cardioprotection. This study examined whether mitoKCa channel involved protection afforded by ADM.
Summary. In hepatitis C virus (HCV) infection, the Th1‐type immune response is involved in liver injury. A predominance of immunosuppressive regulatory T cells (Treg) hypothesized patients with persistently normal alanine aminotransferase (PNALT). Our aim was to clarify role Treg pathogenesis PNALT. Fifteen chronically HCV‐infected PNALT, 21 elevated ALT (CH) and 19 healthy subjects (HS) were enrolled. We determined naturally‐occurring (N‐Treg) as CD4+CD25high+FOXP3+ cells. The expression...