- Plant Pathogens and Fungal Diseases
- Mycorrhizal Fungi and Plant Interactions
- Fungal Infections and Studies
- Antifungal resistance and susceptibility
- Yeasts and Rust Fungi Studies
- Nail Diseases and Treatments
- Infectious Diseases and Mycology
- Lichen and fungal ecology
- Fungal Biology and Applications
- Plant and animal studies
- Turtle Biology and Conservation
- Plant Pathogens and Resistance
- Ocular Infections and Treatments
- Amphibian and Reptile Biology
- Insect and Pesticide Research
- Forest Insect Ecology and Management
- Microbial infections and disease research
- Mycotoxins in Agriculture and Food
- Insect and Arachnid Ecology and Behavior
- Entomopathogenic Microorganisms in Pest Control
- Plant Disease Resistance and Genetics
- Aquaculture disease management and microbiota
- Genomics and Phylogenetic Studies
- Chemical synthesis and alkaloids
- Plant Pathogenic Bacteria Studies
University of Alberta
2011-2021
University of Toronto
2002-2020
The University of Texas Health Science Center at San Antonio
1999-2018
University of Antwerp
2018
The University of Texas Health Science Center at Houston
2018
University of Saskatchewan
2018
South Texas Veterans Health Care System
2018
Highland Hospital
2017
University of Manitoba
2017
The University of Texas at San Antonio
2017
In recent years, the Chrysosporium anamorph of Nannizziopsis vriesii (CANV), guarroi, ophiodiicola, and species have been reported as causes dermal or deep lesions in reptiles. These infections are contagious often fatal affect both captive wild animals. Forty-nine CANV isolates from reptiles six human sources were compared with N. based on their cultural characteristics DNA sequence data. Analyses sequences internal transcribed spacer small subunit nuclear ribosomal gene revealed that...
Recent discoveries of novel systemic fungal pathogens with thermally dimorphic yeast-like phases have challenged the current taxonomy Ajellomycetaceae, a family currently comprising genera Blastomyces, Emmonsia, Emmonsiellopsis, Helicocarpus, Histoplasma, Lacazia and Paracoccidioides. Our morphological, phylogenetic phylogenomic analyses demonstrated species relationships their specific phenotypes, clarified generic boundaries provided first annotated genome assemblies to support description...
The family Ajellomycetaceae (Onygenales) includes mammal-associated pathogens within the genera Blastomyces, Emmonsia, Histoplasma and Paracoccidioides, as well recently described genera, Emergomyces that causes disease in immunocompromised hosts, Emmonsiellopsis, known only from soil. To further assess phylogenetic relationships among between members of these several previously undescribed species, we sequenced analyzed DNA-directed RNA polymerase II (rPB2), translation elongation factor...
Abstract Sterile fungi isolated from surface-sterilized roots of the Ericaceae, and hypothesized to be conspecific based primarily on restriction fragment length polymorphisms, were provisionally named as Variable White Taxon (VWT). In preliminary resynthesis trials with Vaccinium myrtilloides or V. vitis-idaea, isolates did not form typical ericoid mycorrhizas. Additional obtained Orchidaceae, Pinaceae, Betulaceae Salicaceae, given informal names such white 1 (SW1), thought represent same...
Pure cultures of endophytic fungi were obtained from the mycorrhizae some native Alberta orchids (Amerorchis rotundifolia, Calypso bulbosa, Coeloglossum viride, Corallorhiza maculata, Platanthera dilatata, P. hyperborea, obtusata). Isolates Rhizoctonia constituted largest group endophytes, but few could be identified to species. One these strains was as repens, a species reported ubiquitous and common mycorrhizal fungus orchids. Another strain produced teleomorph stage Ceratobasidium...
Three cases of fatal cerebral mycosis in males with prior histories intravenous drug use from the United States and Australia are reported. Infection each case was limited to brain abscess; no other sites infection were observed. The fungus seen by histopathology isolated tissue identified as Chaetomium strumarium. This is first report human this species, C. strumarium second species known cause primary infection. unusual among members genus forming ascocarps covered pale, thin-walled,...
Phylogenies inferred from the analysis of DNA sequence data have shown that Onygenales contains clades do not correspond with previously described families. One lineage identified in recent molecular phylogenetic studies includes dimorphic pathogens belonging to genera Ajellomyces, Emmonsia and Paracoccidioides. To evaluate degree support for this determine whether it additional taxa, we examined relationships among members clade selected saprobic onygenalean taxa based on maximum-parsimony...
The Chrysosporium anamorph of Nannizziopsis vriesii (CANV), a keratinophilic fungus that naturally and experimentally causes severe often fatal dermatitis in multiple reptile species, was isolated pure culture from skin samples three inland bearded dragons (Pogona vitticeps) with deep granulomatous dermatomycosis. first animal presented focal maxillary swelling involving the gingiva. This lizard died while undergoing itraconazole topical miconazole therapy. second focally extensive...
Chronic granulomatous disease (CGD) is an inherited disorder of the nicotinamide adenine dinucleotide phosphate oxidase that leads to defective production microbicidal superoxide and other oxidative radicals, resulting in increased susceptibility invasive infections, especially those due fungi.Geosmithia argillacea was identified from cultured isolates by genomic sequencing internal transcribed spacer region. Isolates previously as Paecilomyces variotii, a filamentous fungus closely...
Two recent molecular analyses of morphologically similar fungal isolates formerly grouped under the appellation "Chrysosporium anamorph Nannizziopsis vriesii (CANV) complex" led to major taxonomic revisions and revealed new insights into biology these reptile pathogens. All CANV-complex differed from N. were assigned 16 species, either within or genera Paranannizziopsis Ophidiomyces, 14 species newly described. From revisions, a trend in host specificity clearly emerged that was not...
The taxonomy of the synnematous genera Cephalotrichum, Doratomyces and Trichurus, other related Gamsia, Wardomyces Wardomycopsis, has been controversial relies mainly on morphological criteria. These are microascaceous saprobic fungi mostly found in air soil with a worldwide distribution. In order to clarify their delineate generic boundaries within Microascaceae, we studied 57 isolates that include clinical, environmental all available ex-type strains large set species by means...
We report 4 patients in North America with disease caused by Emergomyces canadensis, a newly proposed species of pathogenic dimorphic fungus. Affected persons were immunocompromised; lived Saskatchewan, Colorado, and New Mexico; had systemic involving blood, skin, cervix, lung, lymph node. Two cases fatal.
Phenotypic similarities between the root endophytes Scytalidium vaccinii, a hyphomycete, and Hymenoscyphus ericae, an ascomycete, led to speculation that S. vaccinii might be anamorph of H. ericae. To test this hypothesis, we used polymerase chain reaction amplify portions ribosomal DNA from ex-type cultures each species several putatively identified as or ericae based on colonial morphological similarities. An initial restriction fragment analysis amplified rDNA separated isolates England...
The presence of clamp connections on hyphae and the development fruiting bodies in culture are primary characters which allow identification basidiomycete Schizophyllum commune cases human infection. diagnostic problems presented by a nonclamped, nonfruiting isolate from dense mass right upper lobe lung female with past history pulmonary tuberculosis diabetes described. Several features isolated fungus, including rapid growth rate white, dense, cottony colonies, tolerance to fungicide...
Coccidioides immitis is an anomaly amongst the human systemic fungal pathogens. Its unique parasitic cycle has contributed to confusion over its taxonomy. Early investigators mistakenly suggested that pathogen a protist, while others agreed it be fungus but placed in four different divisions of Eumycota. The taxonomy C. still unresolved. Ultrastructural examinations and saprobic phases have revealed features are diagnostic ascomycetous fungi. Moreover, striking similarities between kind...