Lynne Sigler

ORCID: 0000-0002-7338-9120
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Plant Pathogens and Fungal Diseases
  • Mycorrhizal Fungi and Plant Interactions
  • Fungal Infections and Studies
  • Antifungal resistance and susceptibility
  • Yeasts and Rust Fungi Studies
  • Nail Diseases and Treatments
  • Infectious Diseases and Mycology
  • Lichen and fungal ecology
  • Fungal Biology and Applications
  • Plant and animal studies
  • Turtle Biology and Conservation
  • Plant Pathogens and Resistance
  • Ocular Infections and Treatments
  • Amphibian and Reptile Biology
  • Insect and Pesticide Research
  • Forest Insect Ecology and Management
  • Microbial infections and disease research
  • Mycotoxins in Agriculture and Food
  • Insect and Arachnid Ecology and Behavior
  • Entomopathogenic Microorganisms in Pest Control
  • Plant Disease Resistance and Genetics
  • Aquaculture disease management and microbiota
  • Genomics and Phylogenetic Studies
  • Chemical synthesis and alkaloids
  • Plant Pathogenic Bacteria Studies

University of Alberta
2011-2021

University of Toronto
2002-2020

The University of Texas Health Science Center at San Antonio
1999-2018

University of Antwerp
2018

The University of Texas Health Science Center at Houston
2018

University of Saskatchewan
2018

South Texas Veterans Health Care System
2018

Highland Hospital
2017

University of Manitoba
2017

The University of Texas at San Antonio
2017

In recent years, the Chrysosporium anamorph of Nannizziopsis vriesii (CANV), guarroi, ophiodiicola, and species have been reported as causes dermal or deep lesions in reptiles. These infections are contagious often fatal affect both captive wild animals. Forty-nine CANV isolates from reptiles six human sources were compared with N. based on their cultural characteristics DNA sequence data. Analyses sequences internal transcribed spacer small subunit nuclear ribosomal gene revealed that...

10.1128/jcm.01465-13 article EN Journal of Clinical Microbiology 2013-08-08

Recent discoveries of novel systemic fungal pathogens with thermally dimorphic yeast-like phases have challenged the current taxonomy Ajellomycetaceae, a family currently comprising genera Blastomyces, Emmonsia, Emmonsiellopsis, Helicocarpus, Histoplasma, Lacazia and Paracoccidioides. Our morphological, phylogenetic phylogenomic analyses demonstrated species relationships their specific phenotypes, clarified generic boundaries provided first annotated genome assemblies to support description...

10.1111/myc.12601 article EN Mycoses 2017-02-07

The family Ajellomycetaceae (Onygenales) includes mammal-associated pathogens within the genera Blastomyces, Emmonsia, Histoplasma and Paracoccidioides, as well recently described genera, Emergomyces that causes disease in immunocompromised hosts, Emmonsiellopsis, known only from soil. To further assess phylogenetic relationships among between members of these several previously undescribed species, we sequenced analyzed DNA-directed RNA polymerase II (rPB2), translation elongation factor...

10.1007/s13225-018-0403-y article EN cc-by Fungal Diversity 2018-05-01

Abstract Sterile fungi isolated from surface-sterilized roots of the Ericaceae, and hypothesized to be conspecific based primarily on restriction fragment length polymorphisms, were provisionally named as Variable White Taxon (VWT). In preliminary resynthesis trials with Vaccinium myrtilloides or V. vitis-idaea, isolates did not form typical ericoid mycorrhizas. Additional obtained Orchidaceae, Pinaceae, Betulaceae Salicaceae, given informal names such white 1 (SW1), thought represent same...

10.3114/sim.53.1.1 article EN cc-by-nc-nd Studies in Mycology 2005-01-01

Pure cultures of endophytic fungi were obtained from the mycorrhizae some native Alberta orchids (Amerorchis rotundifolia, Calypso bulbosa, Coeloglossum viride, Corallorhiza maculata, Platanthera dilatata, P. hyperborea, obtusata). Isolates Rhizoctonia constituted largest group endophytes, but few could be identified to species. One these strains was as repens, a species reported ubiquitous and common mycorrhizal fungus orchids. Another strain produced teleomorph stage Ceratobasidium...

10.1139/b87-336 article EN Canadian Journal of Botany 1987-12-01

Three cases of fatal cerebral mycosis in males with prior histories intravenous drug use from the United States and Australia are reported. Infection each case was limited to brain abscess; no other sites infection were observed. The fungus seen by histopathology isolated tissue identified as Chaetomium strumarium. This is first report human this species, C. strumarium second species known cause primary infection. unusual among members genus forming ascocarps covered pale, thin-walled,...

10.1128/jcm.33.10.2692-2698.1995 article EN Journal of Clinical Microbiology 1995-10-01

Phylogenies inferred from the analysis of DNA sequence data have shown that Onygenales contains clades do not correspond with previously described families. One lineage identified in recent molecular phylogenetic studies includes dimorphic pathogens belonging to genera Ajellomyces, Emmonsia and Paracoccidioides. To evaluate degree support for this determine whether it additional taxa, we examined relationships among members clade selected saprobic onygenalean taxa based on maximum-parsimony...

10.1080/15572536.2005.11832928 article EN Mycologia 2004-07-01

The Chrysosporium anamorph of Nannizziopsis vriesii (CANV), a keratinophilic fungus that naturally and experimentally causes severe often fatal dermatitis in multiple reptile species, was isolated pure culture from skin samples three inland bearded dragons (Pogona vitticeps) with deep granulomatous dermatomycosis. first animal presented focal maxillary swelling involving the gingiva. This lizard died while undergoing itraconazole topical miconazole therapy. second focally extensive...

10.1080/13693780601188610 article EN Medical Mycology 2007-01-01

Chronic granulomatous disease (CGD) is an inherited disorder of the nicotinamide adenine dinucleotide phosphate oxidase that leads to defective production microbicidal superoxide and other oxidative radicals, resulting in increased susceptibility invasive infections, especially those due fungi.Geosmithia argillacea was identified from cultured isolates by genomic sequencing internal transcribed spacer region. Isolates previously as Paecilomyces variotii, a filamentous fungus closely...

10.1093/cid/ciq250 article EN Clinical Infectious Diseases 2011-02-23

Two recent molecular analyses of morphologically similar fungal isolates formerly grouped under the appellation "Chrysosporium anamorph Nannizziopsis vriesii (CANV) complex" led to major taxonomic revisions and revealed new insights into biology these reptile pathogens. All CANV-complex differed from N. were assigned 16 species, either within or genera Paranannizziopsis Ophidiomyces, 14 species newly described. From revisions, a trend in host specificity clearly emerged that was not...

10.5818/1529-9651-26.1-2.46 article EN Journal of Herpetological Medicine and Surgery 2016-03-01

The taxonomy of the synnematous genera Cephalotrichum, Doratomyces and Trichurus, other related Gamsia, Wardomyces Wardomycopsis, has been controversial relies mainly on morphological criteria. These are microascaceous saprobic fungi mostly found in air soil with a worldwide distribution. In order to clarify their delineate generic boundaries within Microascaceae, we studied 57 isolates that include clinical, environmental all available ex-type strains large set species by means...

10.1016/j.simyco.2016.07.002 article EN cc-by-nc-nd Studies in Mycology 2016-03-01

We report 4 patients in North America with disease caused by Emergomyces canadensis, a newly proposed species of pathogenic dimorphic fungus. Affected persons were immunocompromised; lived Saskatchewan, Colorado, and New Mexico; had systemic involving blood, skin, cervix, lung, lymph node. Two cases fatal.

10.3201/eid2404.171765 article EN cc-by Emerging infectious diseases 2018-03-01

Phenotypic similarities between the root endophytes Scytalidium vaccinii, a hyphomycete, and Hymenoscyphus ericae, an ascomycete, led to speculation that S. vaccinii might be anamorph of H. ericae. To test this hypothesis, we used polymerase chain reaction amplify portions ribosomal DNA from ex-type cultures each species several putatively identified as or ericae based on colonial morphological similarities. An initial restriction fragment analysis amplified rDNA separated isolates England...

10.1080/00275514.1992.12026271 article EN Mycologia 1993-03-01

The presence of clamp connections on hyphae and the development fruiting bodies in culture are primary characters which allow identification basidiomycete Schizophyllum commune cases human infection. diagnostic problems presented by a nonclamped, nonfruiting isolate from dense mass right upper lobe lung female with past history pulmonary tuberculosis diabetes described. Several features isolated fungus, including rapid growth rate white, dense, cottony colonies, tolerance to fungicide...

10.1128/jcm.33.8.1979-1983.1995 article EN Journal of Clinical Microbiology 1995-08-01

Coccidioides immitis is an anomaly amongst the human systemic fungal pathogens. Its unique parasitic cycle has contributed to confusion over its taxonomy. Early investigators mistakenly suggested that pathogen a protist, while others agreed it be fungus but placed in four different divisions of Eumycota. The taxonomy C. still unresolved. Ultrastructural examinations and saprobic phases have revealed features are diagnostic ascomycetous fungi. Moreover, striking similarities between kind...

10.1099/00221287-140-6-1481 article EN Microbiology 1994-06-01
Coming Soon ...