Abstract Background and objectives Family caregivers play a curial role in supporting caring for their mentally ill relatives. Their struggle facing stigma shouldering caregiving burden is marginalized, undervalued, invisible to medical services. This study assessed the of mental illnesses, correlates among family patients. Methods A cross-sectional design was used collect data from 425 main patients at Assiut University Hospital. structured interview questionnaire designed socio-demographic...

Background: Nursing students may be particularly exposed to the psychological consequences of climate change due their emphasis on future and chance that would alter career paths. Aim: To assess related depression, anxiety, stress among nursing students. Research design: A descriptive correlational research design was used in this study. Setting: The study carried out at faculty nursing, Assiut University. Sample: random, stratified sample 330 included Tools: Demographic characteristics...

Abstract Background Mental illness is associated with misunderstanding and unfavorable attitude worldwide. The belief in its spiritual nature made traditional healers the main service consultants for mentally ill patients. present study a cross-sectional conducted among 425 family caregivers of patients at Assiut University Hospital. objective was to assess caregivers’ knowledge towards mental as well their health-seeking behavior relatives. Results studied had low scores illness. Age...

Background: The COVID-19 pandemic has imposed several challenges on different populations all around the world, with stress being identified as one of major challenges. This study aims to investigate impact COVID-19-induced prevalence and severity anxiety and/or depression, factors that predict development coping strategies in Egyptian population during COVID 19 outbreak. Subjects Methods: is an observational cross-sectional online study. questionnaire our included five sections: demographic...

Schizophrenia is a typical N-methyl-d-aspartate receptor (NMDA-R) hypofunction disorder. Decreased d-serine (d-Ser) levels in the periphery occur schizophrenia and may reflect decreased availability of d-Ser to activate NMDA-R brain.The objective this study was investigate role metabolism pathogenesis via biochemical assays correlates, serum level d-Ser, racemase (SR) (responsible for its formation from l-serine [l-Ser]) d-amino acid oxidase (DAAO) catabolism), among different clinical types...

Abstract Background One of the most consistent findings in childhood psychopathology literature is that children with dyslexia frequently presented additional psychiatric disorders. Over 60% meets criteria for at least one diagnosis. Aim results Dyslexia shows high comorbidity ADHD, ODD, and CD (18%, 14%, 8%, respectively) than ccontrols affect dyslexic boys more girls. Dyslexic group show marked increase internalizing externalizing syndromes control group. girls behaviors boys, unlike which...

Abstract Introduction Beta-thalassemia is a prevalent autosomal recessive haemolytic disorder, particularly in the Middle East. Patients with beta-thalassemia major (βTM) require iron chelation therapy and regular blood transfusions, while those intermedia (βTI) exhibit milder symptoms. This study aimed to evaluate cognitive function, behavioural problems, quality of life, related aspects individuals βTM βTI. Methods The cross-sectional included 20 participants, βTI 19 healthy controls....

Abstract Background Most autism spectrum disorder (ASD) interventions evaluated child outcomes and ignoring the role of parent family factors on both immediate- long-term effects therapy. The purpose this study was to determine relationship between stigma, mental health problems, quality life burden in families children with ASD Egypt its risk factors. Seventy parents were recruited from two intervention centers. Participants divided into groups based scale: caregivers moderate ( n = 27)...

Abstract Background Breast cancer is the most frequent among women, impacting 2.1 million women each year. The aim of study to determine prevalence sleep disorders patients with breast cancer, its correlation different psychological symptoms and ability such predict those patients. current a case-control compromised 153 participants, 93 versus 60 cross-matched healthy control persons recruited from outpatient clinic Oncology Department—Assiut University Hospital. Arabic versions Beck’s...

Abstract Background Studies show that autism spectrum disorder and attention-deficit hyperactivity place a significant stigma burden on caregivers, economically as well socially, psychologically, emotionally. The current study aims to assess caregivers of those children with reference disease burden, evaluation different psychiatric symptoms, quality life. Also, it compare the extent such disruption related type (ASD versus ADHD). A cross-sectional, analytical was designed including 72 {38...

Abstract Background Epilepsy has significant effects on the behavior of most people who suffer it. In some cases, seizure activity itself is manifested as a brief change in that might appear unusual to casual observer. Evidence also suggests epilepsy can affect when seizures are not occurring. Descriptions inter-ictal with have long and controversial history. The study aims assess personality disorders among epileptic patients impact severity traits. Methods: This conducted upon 90 presented...

Abstract Background Tramadol is a centrally active synthetic opioid analgesic that used extensively among Egyptian males for premature ejaculation as self-medication. The present work conducted to outline male sex hormone affection in patients with tramadol dependence and its relation sexual satisfaction. Results Tramadol-dependent have significantly lower mean serum level of testosterone compared the control group Sexual Satisfaction Scale than group. Conclusions results provide evidence...

Abstract Background Tramadol hydrochloride is a centrally acting analgesic drug that has turned out to be of growing interest due its success in the management pain humans. By considering twin mechanism action tramadol, as activation opioid and monoaminergic systems, potential immunological effects this should considered evaluated. Studies show induces an improvement postoperative immune suppression increases NK cell activity, lymphocyte proliferation, IL-2 production which may linked...

Objective Behcet’s disease (BD) is a chronic autoimmune multisystemic vasculitis of unknown cause that affects one case per 170 000 persons in the USA. There are few studies literature targeted BD patient group for cognitive and psychological evaluation scarce evaluated patients with without neurological manifestations. In this study, we aimed to assess those who have manifestations impairments. Patients methods A case–control study was conducted. total 45 consecutive adult patients, aged...

Background: Behcet’s disease (BD) is a chronic multi-systemic autoinflammatory associated with increase prevalence of psychiatric comorbidity (Ilhan et al. 2016 ). Pro-inflammatory cytokines have been reported to be elevated in patients depression and anxiety. IL-23/IL-17 axis has shown play remarkable role pathogenesis BD, anxiety (Sugita 2012, Gheita 2015 However, the relation between serum level interleukin (IL)-17 IL-23 incidence cognitive impairment, Behcet are still unknown....

Abstract Background Several studies have observed that painful diabetic peripheral polyneuropathy (PDPN) had an impact on the level of functioning domains and quality sleep as well cognitive functions. This study is aimed to explore relationship between severity pain functioning, quality, functions among these patients. We recruited 100 diabetics with a mean HbA1C% 7.3±0.9, diagnosed PDPN, included in age 51±12.8 years disease duration 10.2±7.4 years. The following assessment was done for...

Background and Objectives: Studies show that ASD ADHD places a significant stigma burden on caregivers, economically as well socially, psychologically, emotionally. The current study aims to assess caregivers of children regard disease burden, evaluation their mental health characteristics quality life. Also, the compare extend such disruption related type disorder (ASD versus ADHD).Methods: cross sectional, analytic includes 72 {38 Caregivers Autism 34 ADHD} assessed for 1-stigma using...