A5101888803- Plant Molecular Biology Research
- Plant Gene Expression Analysis
- Plant Stress Responses and Tolerance
- Plant biochemistry and biosynthesis
- Horticultural and Viticultural Research
- Liver Disease Diagnosis and Treatment
- Chronic Lymphocytic Leukemia Research
- Plant Reproductive Biology
- Obstructive Sleep Apnea Research
- Photosynthetic Processes and Mechanisms
- Plant Physiology and Cultivation Studies
- Postharvest Quality and Shelf Life Management
- Electrolyte and hormonal disorders
- Reproductive System and Pregnancy
- Immune Cell Function and Interaction
- Tracheal and airway disorders
- Folate and B Vitamins Research
- Cleft Lip and Palate Research
- Plant responses to water stress
- Lung Cancer Diagnosis and Treatment
- Alcohol Consumption and Health Effects
- Assisted Reproductive Technology and Twin Pregnancy
- Pregnancy and preeclampsia studies
- HIV Research and Treatment
- Flowering Plant Growth and Cultivation
Second Affiliated Hospital of Xinjiang Medical University
2025
Xinjiang Medical University
2025
Sun Yat-sen Memorial Hospital
2025
Sun Yat-sen University
2018-2025
Capital Medical University
2013-2024
Beijing Obstetrics and Gynecology Hospital
2019-2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2012-2024
Shenyang Agricultural University
2020-2024
Institute of Chemical Technology
2023
Jilin University of Chemical Technology
2023
AIMTo determine whether oral administration of Bifidobacterium infantis CGMCC313-2 (B.infantis CGMCC313-2) inhibits allergen-induced airway inflammation and food allergies in a mouse model. METHODSOvalbumin (OVA)-induced allergic asthma b-lactoglobulin-induced allergy models were used this study.Following B. during or after allergen sensitization, histopathologic changes the lung intestine
To understand the relationships between nuclear organization and gene expression in a model system, we employed three-dimensional imaging chromatin immunoprecipitation (ChIP)-chromosome conformation capture (3C) techniques to investigate topographies of immunoglobulin ( Ig ) genes transcripts during B-cell development. Remarkably, plasma cells, when antibody synthesis peaks, active residing on three different chromosomes exhibit pronounced colocalizations transcription factories, often near...
Abstract The SPL gene is a plant-specific transcription factor involved in the regulation of plant growth and development, which have been identified woody plants. process floral bud differentiation affects timing flowering fruit set regulates growth, however, mechanism flower development by genes less studied. In this study, 56 VcSPL were tetraploid blueberry. family was classified into six subfamilies, analysis cis-elements showed that regulated light, phytohormones (abscisic acid, MeJA),...
Rice is one of the major staple cereals in world, but heat stress increasingly threatening its yield. Analyzing thermotolerance mechanism from new thermotolerant germplasms very important for rice improvement. Here, physiological and transcriptome analyses were used to characterize difference between two germplasms, heat-sensitive MH101 heat-tolerant SDWG005. Two genotypes exhibited diverse responses pollen viability, pollination characteristics, antioxidant enzymatic activity leaves...
Background Worldwide cultivation of maize is often impacted negatively by drought stress. Hyperosmolality-gated calcium-permeable channels (OSCA) have been characterized as osmosensors in Arabidopsis . However, the involvement members OSCA ( ZmOSCA ) gene family response to stress unknown. It furthermore unclear which plays a major role genetic improvement tolerance Maize. Methods We predicted protein domain structure and transmembrane regions using NCBI Conserved Domain Database database...
Abstract Kiwifruit has gained increasing attention worldwide for its unique flavor and high nutritional value. Rapid softening after harvest greatly shortens shelf-life reduces the commercial Therefore, it is imperative urgent to identify clarify mechanism. This study aimed analyze compare long noncoding RNA (lncRNA) mRNA expression patterns in ABA-treated (ABA) room temperature (RT)-stored fruits with those freshly harvested (CK) as control. A total of 697 differentially expressed genes...
SUMMARY Anthocyanin is an important pigment responsible for plant coloration and beneficial to human health. Kale ( Brassica oleracea var. acephala ), a primary cool‐season flowers vegetables, ideal material study anthocyanin biosynthesis regulation mechanisms due its anthocyanin‐rich leaves. However, the underlying molecular mechanism of accumulation in kale remains poorly understood. Previously, we demonstrated that BoDFR1 key gene controlling kale. Here, discovered 369‐bp InDel variation...
Background and purpose Current studies have substantiated the sparing effect of ultra-high dose rate irradiation (FLASH) in various organs including brain, lungs, intestines. Whether this extends to esophageal tissue remains unexplored. This study aims compare different responses histological protein expression levels following conventional (CONV) FLASH ascertain presence a effect. Methods materials C57 female mice were randomly divided into three groups: control, CONV, groups. The chest...
Abstract Background and Aim With the changes in diet structure lifestyle, incidence of fatty liver disease is increasing C hina, especially cities. The goal present study was to accurately determine prevalence risk factors B eijing residents, hina. Methods By using random multistage stratification cluster sampling, residents aged > 20 years Dongcheng District Tongzhou were recruited, questionnaire survey, physical examination, detection fasting glucose, blood lipids biochemistry,...
Anticancer drug-induced interstitial lung disease (DIILD) has received increasing clinical attention, and the quality of relevant guidance documents become critical. Our purpose was to assess for anticancer DIILD summarize recommendations. Clinical practice guidelines (CPGs) consensus statements with recommendations were searched in electronic databases, websites guideline organizations, professional societies. The assessed using Appraisal Guidelines Research & Evaluation II (AGREE II)...
Atherosclerosis (AS) is emerging as a major global public health problem. Researchers are developing and implementing various anti-AS strategies. This study aimed to investigate gut microbiota metabolite changes associated with elevated serum low-density lipoprotein cholesterol (LDL-c). Mice were divided into two equal groups: Group C (mice from healthy subjects) B AS). At the end of 8-week study, blood samples collected for lipid analysis; rectal feces microbial 16S rRNA sequencing analysis...
Antibody-drug conjugates (ADCs) have demonstrated remarkable therapeutic efficacy in refractory cancers, however, ophthalmotoxicity remains a serious concern. This study aimed to investigate the association between ADCs and ophthalmotoxicity. A retrospective pharmacovigilance was conducted utilizing data extracted from U.S. Food Drug Administration Adverse Events Reporting System (FAERS) 2004 2023. Disproportionality analyses were performed using reporting odds ratio (ROR) information...
Kiwifruit (Actinidia spp.) is susceptible to waterlogging stress. Although abundant wild germplasm resources exist among Actinidia plants for improving the tolerance of kiwifruit cultivars, underlying mechanisms remain largely unknown. Here, a comparative study was undertaken using one germplasm, Maorenshen (A. valvata Dunn, MRS), and cultivar, Miliang-1 chinensis var. deliciosa (A.Chev.) A.Chev. cv. Miliang-1, ML). Under stress, ML plantlets were seriously damaged with wilted chlorotic...
The rhizomes and tubers of Curcuma kwangsiensis have extensive medicinal value in China. However, the inflorescences C. are rarely known horticulture, because its low field flowering rate. In order to improve rate kwangsiensis, we conducted drought stress treatment on rhizome kwangsiensis. was highest after 4d treatment, buds could be obviously swell 4th day rehydration culture. identify genes regulating time comparative transcriptome analysis performed before 4 d During this process, a...
Abstract A de novo transcriptome analysis was performed in C. album, a temperature sensitive fruit tree China, after treatment with varied temperatures. total number of 168,385 transcripts were assembled, comprising 109,439 unigenes, which 70,530 successfully annotated. Compared control check group (CK), treated under 25 °C, the chilling stress (4 °C) (CT), showed about 2810 up-regulated and 2567 down-regulated genes. Whereas, freezing (− 3 (FT) an up-regulation down-regulation 1748 1459...
Abstract Background Although acetaminophen is widely used in women during pregnancy, its safety has not been clearly stated. The study aimed to investigate the association between use and adverse pregnancy outcomes pregnant China. Methods We conducted a retrospective cohort by collecting data on who delivered Beijing Obstetrics Gynecology Hospital from January 2018 September 2023. An group control were formed based prenatal exposure acetaminophen. that we focused stillbirth, miscarriage,...