A5051030911- Mass Spectrometry Techniques and Applications
- Breast Implant and Reconstruction
- Breast Cancer Treatment Studies
- Advanced Proteomics Techniques and Applications
- Body Contouring and Surgery
- Metabolomics and Mass Spectrometry Studies
- Ion-surface interactions and analysis
- Analytical chemistry methods development
- Wireless Body Area Networks
- Molecular Communication and Nanonetworks
- Breast Lesions and Carcinomas
- Advanced Optical Sensing Technologies
Tampere University
2018-2022
Fimlab (Finland)
2022
Tampere University Hospital
2018
The primary treatment of breast cancer is the surgical removal tumor with an adequate healthy tissue margin. An intraoperative method for assessing margins could optimize resection. Differential ion mobility spectrometry (DMS) applicable analysis and allows differentiation malignant benign tissues. However, number cells necessary detection remains unknown. We studied threshold DMS cell identification a widely characterized line (BT-474) dispersed in human myoma-based microenvironment...
Background and Aims: Reduction mammoplasty alleviates macromastia symptoms improves quality of life. We investigated a large series consecutive reduction mammoplasties to assess various risk factors for both minor major complications after the procedure. Materials Methods: A retrospective analysis 453 was performed between 2007 2010 at an academic tertiary referral center evaluate complications. Results: The incidence 40.5% 8.8%, respectively. Patients with had significantly higher mean body...
Abstract Background and Objectives Optimal margins for ductal carcinoma in situ (DCIS) remain controversial breast‐conserving surgery (BCS) mastectomy. We examine the association of positive margins, reoperations, DCIS age. Methods A retrospective study histopathological reports (4489 patients). Margin positivity was defined as ink on tumor invasive carcinoma. For DCIS, we applied 2 mm anterior side margin thresholds, posterior margin. Results The incidence 20% BCS 5% mastectomies ( p <...
Pathological gross examination of breast carcinoma samples is sometimes laborious. A tissue pre-mapping method could indicate neoplastic areas to the pathologist and enable focused sampling. Differential Mobility Spectrometry (DMS) a rapid affordable technology for complex gas mixture analysis. We present an automated laser analysis system imaging approaches (iATLAS), which utilizes computer-controlled evaporator unit coupled with DMS analyzer. The demonstrated in classification porcine...
Effective surgical margin assessment is paramount for good oncological outcomes and new methods are in active development. One emerging approach the analysis of chemical composition smoke from tissues. Surgical typically removed with a evacuator to protect operating room staff its harmful effects respiratory system. Thus, evacuated without disturbing operation feasible approach. Smoke transportation subject lags that affect system usability. We analyzed delay evaluated tissue classification...