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Contact & Profiles
A5013125223
Research Areas
- Ubiquitin and proteasome pathways
- RNA modifications and cancer
- Genomics and Chromatin Dynamics
- NF-κB Signaling Pathways
- Peptidase Inhibition and Analysis
- RNA Research and Splicing
- Cancer-related gene regulation
York University
2017-2021
Transcription-related proteins are frequently identified as targets of sumoylation, including multiple subunits the RNA polymerase II (RNAPII) general transcription factors (GTFs). However, it is not known how sumoylation affects GTFs or whether they sumoylated when assemble at promoters to facilitate RNAPII recruitment and initiation. To explore can regulate genome-wide, we performed SUMO ChIP-seq in yeast found, agreement with others, that most chromatin-associated detected genes encoding...
10.1371/journal.pgen.1009828
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PLoS Genetics
2021-09-29
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