- Blockchain Technology Applications and Security
- Statistical Methods and Inference
- Telemedicine and Telehealth Implementation
- Ethics in Clinical Research
- Genetic factors in colorectal cancer
- Digital Mental Health Interventions
- Bayesian Methods and Mixture Models
- Scientific Computing and Data Management
- Statistical Distribution Estimation and Applications
- Statistical Methods in Clinical Trials
- Ethics and Social Impacts of AI
University of Missouri
2020-2025
In oncology studies, the assumption of proportional hazards is often questionable due to factors such as presence cured patients, a delayed treatment benefit, and possible switching. The restricted mean survival time (RMST) has emerged valuable alternative summary measure hazard ratio (HR) in this scenario it provides clinically meaningful interpretation benefit without additional assumptions. As commonly used primary endpoint, progression-free (PFS) defined from randomization first...
A clinical trial management system (CTMS) is a suite of specialized productivity tools that manage processes from study planning to closeout. Using CTMSs has shown remarkable benefits in delivering efficient, auditable, and visualizable trials. However, the current CTMS market fragmented, most fail meet expectations because their inability support key functions, such as inconsistencies data captured across multiple sites. Blockchain technology, an emerging distributed ledger considered...
<sec> <title>BACKGROUND</title> A clinical trial management system (CTMS) is a suite of specialized productivity tools that manage processes from study planning to closeout. Using CTMSs has shown remarkable benefits in delivering efficient, auditable, and visualizable trials. However, the current CTMS market fragmented, most fail meet expectations because their inability support key functions, such as inconsistencies data captured across multiple sites. Blockchain technology, an emerging...