A5100411133- Statistical Methods and Inference
- Statistical Methods and Bayesian Inference
- Statistical Distribution Estimation and Applications
- Advanced Statistical Methods and Models
- Diabetic Foot Ulcer Assessment and Management
- Statistical Methods in Clinical Trials
- Bayesian Methods and Mixture Models
- Breast Cancer Treatment Studies
- Algebraic structures and combinatorial models
- Dementia and Cognitive Impairment Research
- Advanced Topics in Algebra
- Botulinum Toxin and Related Neurological Disorders
- Global Cancer Incidence and Screening
- Shoulder Injury and Treatment
- Advanced Causal Inference Techniques
- Ectopic Pregnancy Diagnosis and Management
- Nonlinear Waves and Solitons
- Pregnancy and preeclampsia studies
- Cancer Genomics and Diagnostics
- Endoplasmic Reticulum Stress and Disease
- Cancer Cells and Metastasis
- Cancer-related cognitive impairment studies
- Advanced Statistical Process Monitoring
- Health Systems, Economic Evaluations, Quality of Life
- Tensor decomposition and applications
Washington University in St. Louis
2016-2025
University of Virginia
2024-2025
China Pharmaceutical University
2024
First Affiliated Hospital of Shihezi University Medical College
2024
Hospital for Special Surgery
2024
University School
2024
Chongqing University
2024
Columbia University
2022-2023
Chengdu University of Traditional Chinese Medicine
2022
Anhui University
2013-2022
To assess the impact of early triggered palliative care consultation on outcomes high-risk ICU patients.Single-center cluster randomized crossover trial.Two medical ICUs at Barnes Jewish Hospital.Patients (n = 199) admitted to from August 2017 May 2018 with a positive screen indicating high risk for morbidity or mortality.The were intervention usual followed by washout and crossover, independent assignment patients each admission. Intervention arm received an interprofessional team led...
Evaluate the effectiveness of genicular nerve radiofrequency ablation (GNRFA) for chronic knee pain using Patient-Reported Outcomes Measurement Information System Global Health, Physical Health score (PROMIS-GH-PH). Patients who underwent GNRFA at a tertiary academic center were identified by CPT code query and contacted consent. Demographic, clinical, procedural characteristics collected from electronic medical record participants with baseline PROMIS-GH-PH scores. Outcome data standardized...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTCrystal structure of an electron-transfer complex between methylamine dehydrogenase and amicyaninLongyin Chen, Rosemary Durley, Barbara J. Poliks, Kensaku Hamada, Zhiwei F. Scott Mathews, Victor L. Davidson, Yoshinori Satow, Eric Huizinga, Cite this: Biochemistry 1992, 31, 21, 4959–4964Publication Date (Print):June 1, 1992Publication History Published online1 May 2002Published inissue 1 June 1992https://doi.org/10.1021/bi00136a006RIGHTS &...
Core needle biopsy (CNB) and fine-needle aspiration (FNA) are increasingly replacing excisional lymph node in the diagnosis of lymphomas. However, evaluation CNB FNA remains challenging owing to limited architectural information more detailed subclassification lymphomas required by WHO Classification Tumours Haematopoietic Lymphoid Tissues. Our study is largest assess diagnostic accuracy conjunction with ancillary studies. We analyzed 263 cases a was established 237, which 193 were...
Two novel cytotoxic and antifungal constituents, (4S,6S)-6-[(1S,2R)-1, 2-dihydroxybutyl]-4-hydroxy-4-methoxytetrahydro-2H-pyran-2-one (1), (6S,2E)-6-hydroxy-3-methoxy-5-oxodec-2-enoic acid (2), together with three known compounds, LL-P880γ (3), LL-P880α (4), Ergosta-5,7,22-trien-3b-ol (5) were isolated from the metabolites of endophytic fungi Dendrobium officinale. The chemical structures determined based on spectroscopic methods. All compounds 1–5 evaluated by cytotoxicity effects. Our...
Abstract Background. Current literature reports widely different rates of distant metastasis at presentation for squamous cell carcinoma the head and neck (SCCHN). We used Surveillance Epidemiology End Results (SEER) database to determine rate risk factors metastasis. Methods. identified patients with SCCHN diagnosed between 1988 2003. The was determined then stratified by tumor site, size, nodal status. To evaluate contribution each individual factor, both univariate multivariate analyses...
Significance Apparent mineralocorticoid excess, a rare autosomal recessive disorder characterized by low renin hypertension, may display severe or mild phenotype in patients. The variability clinical presentation stems from different extents of impairment the 11β-hydroxysteroid dehydrogenase type 2 (HSD11B2) enzyme arising distinct mutations encoding gene. computational model HSD11B2 protein that we constructed here will be useful predicting disease severity for newly reported missense this
In recent years, research has increasingly focused on the microenvironment of classical Hodgkin lymphoma (CHL) as a predictor treatment outcome. The focus this study was to assess interobserver reproducibility in interpreting macrophage-associated immunohistochemistry (IHC) for CD68 and CD163 retrospective cohort 88 patients with CHL.Staining results were correlated clinical outcome all those high international prognostic score (IPS).The intraclass correlation (ICC) five hematopathologists...
Abstract Johnson proposed some modified t tests to assess the mean of asymmetrical distributions. The were suggested for any parent distribution ranging from normal a as asymmetric an exponential sample sizes small 13. In many practical situations skewness can be greater than those studied by and quite small, possibly 10, due cost sampling procedures. these cases Johnson's test inaccurate. Sutton composite improve upper-tailed test. this article new procedure is positively skewed...
Wolfram syndrome (WFS) is a rare autosomal recessive disease with clinical manifestations of diabetes mellitus (DM), insipidus (DI), optic nerve atrophy (OA) and sensorineural hearing loss (SNHL). Although SNHL key symptom WFS, there limited information on its natural history using standardized measures. Such important for care determining use as an outcome measure in trials. Standardized audiologic measures, including pure-tone testing, tympanometry, speech perception, the unaided Speech...
Background: This study aims to investigate whether maternal SARS-CoV-2 status affects placental pathology. Methods: A retrospective case-control was conducted by reviewing charts and slides of placentas delivered between April 1 July 24, 2020. Clinical history "COVID-19" searched in Pathology Database (CoPath). Controls were matched with SARS-CoV-2-negative women singleton deliveries the 3rd-trimester. Pathological features extracted from pathology reports. Results: Twenty-one 3rd trimester...
Background: Although metatarsophalangeal joint (MTPJ) arthrodesis is considered the “gold standard” for treatment of advanced MTPJ arthritis, a modified oblique Keller capsular interposition arthroplasty (MOKCIA) an alternative hallux rigidus that retains motion. We aim to retrospectively compare long-term patient-reported outcomes, radiographic alignment, walking kinematics, and plantar pressure between MOKCIA rigidus. Methods: Thirty-five patients were recruited from retrospective chart...
ABSTRACT Elementary science education, particularly in the 4th and 5th grades, is essential for setting foundation lifelong learning, fostering critical thinking, preparing students success science, technology, engineering, mathematics (STEM) fields. This stage especially with disabilities, as achievement gaps between them their peers emerge during elementary school. Despite this importance, little known about how taught classrooms these years, disabilities. To address gap, we surveyed...
Introduction: Aspiration of a posttraumatic hemarthrosis has been postulated to improve pain and reduce the burden proinflammatory cytokines chemokines that accumulate in aftermath an acute anterior cruciate ligament injury. However, clinical implications routine aspiration have not fully investigated. The purpose this study was determine effect preoperative on (1) development arthrofibrosis (2) overall revision surgery rate following ACL reconstruction (ACLr). Methods: population interest...
The prevalence of vitamin D deficiency among patients with cancer has been previously reported. Because is fat soluble, pancreatic adenocarcinoma may have an especially high risk in association ongoing and varying degrees malabsorption. However, little known about the correlation between status prognosis these patients.We conducted a retrospective review who were treated at Siteman Cancer Center. Patients' demographic information, clinical staging time assessment, levels, survival data...
Abstract Background Severe obstetric haemorrhage caused by placenta accreta spectrum (PAS) results in significant maternal morbidity and mortality. The effectiveness of prophylactic balloon occlusion the internal iliac artery PAS patients remains controversial. Therefore, we conducted a retrospective case-control study to investigate clinical this treatment. Methods data 104 with complicated previa who delivered caesarean section between January 2016 2019 were collected, divided into two...
Cannabis sativa (C. sativa) leaves are rich in cannabinoids and flavonoids, which play important antioxidant roles. Since the environmental factors may influence accumulation of antioxidants herbal medicines, affects their activity, this study aimed to investigate correlation between chemical composition C. geographical origin activity. Firstly, a high-resolution mass spectrometry method assisted by semi-quantitative feature-based molecular networking (SQFBMN) was established for...
Wolfram syndrome is a rare disease caused by mutations in the WFS1 gene leading to symptoms early mid-childhood. Brain structural abnormalities are present even young children, but it not known when these arise. Such information critical determining optimal outcome measures for clinical trials and understanding aberrant neurobiological processes syndrome. Using voxel-wise regional longitudinal analyses, we compared brain volumes patients (n = 29; ages 5-25 at baseline; mean follow-up 3.6...
Remote limb ischemic conditioning (RLIC) is a clinically feasible method in which brief, sub-lethal bouts of ischemia protects remote organs or tissues from subsequent injury. A single session RLIC can improve exercise performance and increase muscle activation. The purpose this study, therefore, was to assess the effects two-week protocol repeated combined with strength training on gain neural adaptation healthy young adults. Participants age 18–40 years were randomized receive either plus...