Background: Insulin-regulated aminopeptidase (IRAP) is involved in insulin sensitivity and glucose metabolism important the pathophysiology of type 2 diabetes. Serum IRAP levels are strongly associated with diabetes resistance. The aim this study was to evaluate level as a potential biomarker for early diagnosis management resistance women gestational mellitus (GDM). Methods: This cohort included 40 GDM healthy pregnancies. Maternal serum were measured enzyme-linked immunosorbent assay...

Cytoreductive surgery (CRS) is the most important treatment method that increases survival in advanced-stage ovarian cancer (OC) patients. However, complications after CRS are seen as a significant cause of morbidity and mortality. Preoperative risk assessment patients great importance. In recent years, inflammatory markers have been subject many studies evaluating malignancy surgical outcomes. Ca125, Neutrophil-lymphocyte ratio (NLR), platelet-lymphocyte (PLR), Monocyte-lymphocyte (MLR),...

SUMMARY OBJECTIVE: The aim of this study was to compare the efficiency fetal thymic-thoracic ratio and thymus transverse diameter measurements in gestational diabetes mellitus. METHODS: Fetal were assessed 360 pregnant women. Patients examined two groups: 180 mellitus (study group) healthy women (control group). RESULTS: There no statistically significant differences between cases with control group terms diameter; however, found be significantly lower compared that (p<0.001). CONCLUSION: is...

Catestatin can inhibit catecholamine release from chromaffin cells and adrenergic neurons. also have a strong vasodilator effect. This may be useful in understanding the pathophysiology of preeclampsia its treatment. In this study, we investigated serum catestatin levels pregnant women with without preeclampsia. Fifty consecutive mild preeclampsia, 50 severe 100 gestational age-matched (±1 week) uncomplicated pregnancy were evaluated cross-sectional study. Mean was significantly increased...

Many people grieve in a resilient manner, often having sense of equilibrium restored within six months. The most devastating type loss is usually considered to be the death child. For such loss, bereavement may take period distressing years with signs and symptoms that are related grief. There have been different phases identified grieving process, this process encompasses various difficulties levels psychological effects. Women perinatal losses can suffer long periods purpose study was...

Ovarian torsion is a common cause of local ischemic damage, reduced follicular activity and infertility. This study aimed to investigate how well platelet-rich plasma (PRP) protects against experimental (I) ischemia-reperfusion (I/R) injury in rat ovaries its effect on vitro fertilization (IVF) outcomes.Fifty-six adult female Sprague-Dawley albino rats were randomly assigned six groups eight animals each: Sham, Ischemia, I/R, Sham + PRP, I I/R PRP. The remaining used prepare the ischemia...

This study aimed to evaluate the effects of propofol and dexmedetomidine over different timescales on IVF outcomes for transvaginal oocyte retrieval (TVOR). Twenty-four rats included in were divided into two main groups three subgroups subjected ovulation induction process. Group 1 was administered (100 mg/kg i.v.) group 2 (25 µg/kg i.p.) The oviduct collection procedure completed within 15 min subgroup Pro15min, Dex15min (n = 4), 16 30 Pro30min, Dex30min 4) 31 60 Pro60min, Dex60min after...

The study aimed to investigate the effectiveness of aspartate aminotransferase (AST), alanine (ALT), and platelet values in predicting intrahepatic cholestasis pregnancy (ICP) first trimester, together with aminotransferase/platelet ratio index (APRI) score.This consisted a patient group diagnosed ICP (n=49) control (n=62). Laboratory tests both groups were analyzed retrospectively.The first-trimester APRI score AST ALT found be statistically significantly higher than those group. value was...

BACKGROUND/AIMS:The inadequate prenatal and postnatal services due to the deployment of health coronavirus disease-2019 (COVID-19) related arrangements has led an increased number patients experiencing a fear contracting COVID-19 in addition their childbirth.Therefore, this study aimed examine relationship between childbirth. MATERIALS AND METHODS:The was designed descriptive correlational types.Three hundred forty-three pregnant women included using methods were evaluated Fear Scale (CFS)...

To compare the fetal thymic thoracic ratio in preeclamptic pregnant women and healthy women.Fetal was evaluated 240 third trimester. Patients were examined two groups. They included 120 (study group) (control group).The found to be statistically significantly lower cases compared that control group (p = .001). When between mild preeclampsia (0.399 (0.388-0.413)), severe (0.385 (0.350-0.394)), (0.43 (0.324-0.462)), it significant differences groups .001).The decreased this decrease more...

The purpose of this study was to investigate the prevalence anxiety among high-risk pregnant women in late period coronavirus disease 2019 pandemic and evaluate relationship between levels, attitudes-behaviors, coping styles, other psychometric parameters.Pregnant who were followed up our gynecology outpatient clinic evaluated during their admissions November 15, 2020 February 2021. This cross-sectional analyzes prospectively collected data from a university hospital. Inclusion criteria...

Objective Endothelial dysfunction is a major feature of preeclampsia. sVE-cadherin plays role in the preservation and regulation endothelial barrier. For that reason, to evaluation may help elucidate disease pathophysiology

Aim: This study evaluates the role of hematologic inflammatory markers, specifically neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte (PLR), in predicting late-onset fetal growth restriction (FGR). Material Methods: A retrospective comparative analysis was conducted on 76 pregnancies complicated by late- onset FGR 100 healthy as controls. Maternal blood samples were collected, parameters, including NLR PLR, recorded. Data compared markers between control groups to assess...

2019'un sonunda Çin'in Hubei eyaleti Wuhan şehrinde ortaya çıkan ve yayılan SARS-CoV-2 virüsü sonucu meydana gelen COVID-19 pandemisi halen ciddi bir halk sağlığı problemi olarak etkisini sürdürmektedir. Hızlı yayılması, tedavisinin olmaması ölümcül seyretmesi virüsün yarattığı etkiyi önemli kılmaktadır. Pnömoninin maternal morbidite mortalitenin nedeni olduğu düşünüldüğünde, COVID-19'un çıkışı küresel bu salgının gebe kadınlar fetüsleri üzerindeki etkileri hakkında endişeleri artırmıştır....

To compare the size of fetal thymus, using both thymic-thoracic ratio and thymus transverse diameter values in Assisted reproductive technologies (ART) or naturally conceived pregnancies.In this retrospective study, were evaluated 204 pregnant women. Patients examined two groups. The study included 58 Intracytoplasmic sperm injection (ICSI) patients (study group) 146 healthy women (control group).Fetal ART pregnancies found to be statistically significantly lower than that control group (p =...

To evaluate the possible associations between serum Neprilysin (NEP) levels and preeclampsia mild severe subgroups.Fifty-five consecutive women with fifty-five were compared 110 approximately gestational age-matched (±1 week) an uncomplicated pregnancy.Mean NEP was significantly higher in to that of age-matched-controls (231.62 ± 65.30 pg/mL vs. 187.75 84.38 pg/mL, p < 0.001). Mean group its control (228.84 67.26 186.14 85.09 = 0.008); (234.45 63.85 189.29 84.59 0.004). Serum positively...

This study aimed to evaluate the effectiveness of fetal left ventricular modified myocardial performance index in predicting adverse perinatal outcomes for intrahepatic cholestasis pregnancy.A cross-sectional was conducted, including 51 women with pregnancy and 80 healthy controls. Using Doppler ultrasonography, E-wave, A-wave, isovolumetric contraction time, relaxation ejection time were recorded measured.Findings showed that mean index, values statistically significantly higher while E/A...

This study was conducted to determine the fear of birth and coronavirus disease 2019 in pregnant women who applied high-risk pregnancy outpatient clinic during pandemic investigate whether there is a relationship between these fears.

Amaç: Bu araştırmanın amacı bir milyonu aşkın nüfusa hizmet veren jinekolojik onkoloji cerrahisinin yapıldığı üçüncü basamak hastanesine ait pandemi öncesi ve sürecindeki endometrium kanseri vakalarının incelenmesidir.&#x0D; Gereç Yöntem: araştırma ülkemizde başlayan Covid-19 pandemisinden önceki altı ay ile dönemindeki ilk süresinde retrospektif olarak incelendiği kesitsel tipte tanımlayıcı araştırmadır. araştırmada yaş, VKİ, komorbidite, Ca-125 tümör belirteci, çapı, invazyonu, çevre organ...

Objective: To investigate the role of aspartate aminotransferase (AST), alanine (ALT) and platelet values in predicting intrahepatic cholestasis pregnancy (ICP) together with fibrosis-4 (FIB-4) score.Methods: This study consisted a patient group diagnosed ICP (n=44) control (n=53).Laboratory tests both groups were analyzed retrospectively.Receiver operating characteristic (ROC) analysis was performed to determine cut-offs for first trimester FIB-4 score, AST, ALT predict development ICP....

To evaluate the serum levels of serine proteinase inhibitor kallistatin in women with preeclampsia (PE).The clinical and laboratory parameters 55 consecutive early-onset PE (EOPE) late-onset (LOPE) were compared 110 gestational age (GA)-matched (±1 week) pregnant an uncomplicated pregnancy appropriate for fetus.Mean was significantly lower to GA-matched-controls (27.74±8.29 ng/mL vs. 37.86±20.64 ng/mL, p<0.001); EOPE that control group GA-matched (24.85±6.65 33.37±17.46 p=0.002); LOPE...

Introduction: This study aimed to retrospectively evaluate the perinatal outcomes of cases followed up in our clinic for Intrahepatic cholestasis pregnancy (ICP).Methods: In this study, medical records 71 patients who applied Sakarya University Training and Research Hospital, Gynecology Obstetrics Clinic between April 2015 March 2021 were diagnosed with ICP analyzed retrospectively.Results: The mean age was 28.9±4.8years.At time diagnosis, week gestation 31.9±2.4weeks, at birth 36.7±1.5...