A5045894044- Cleft Lip and Palate Research
- Burn Injury Management and Outcomes
- Cutaneous Melanoma Detection and Management
- Reconstructive Surgery and Microvascular Techniques
- Reconstructive Facial Surgery Techniques
- Wound Healing and Treatments
- Nonmelanoma Skin Cancer Studies
- Surgical Sutures and Adhesives
- COVID-19 and healthcare impacts
- Craniofacial Disorders and Treatments
- Bone fractures and treatments
- Animal Virus Infections Studies
- AI in cancer detection
- Full-Duplex Wireless Communications
- Pressure Ulcer Prevention and Management
- Muscle and Compartmental Disorders
- Tracheal and airway disorders
- Antenna Design and Analysis
- Virus-based gene therapy research
- Polyomavirus and related diseases
- Orthopedic Surgery and Rehabilitation
- Ear Surgery and Otitis Media
- Dental Education, Practice, Research
- Breast Implant and Reconstruction
- Global Health Workforce Issues
Morriston Hospital
2013-2024
Swansea Bay University Health Board
2014-2024
Cardiff University
2024
Welsh Centre for Printing and Coating
2024
Royal Hospital for Sick Children
2021
Royal Hospital for Children
2021
Swansea University
2020
Children's Hospital at Westmead
2019
Buckinghamshire Healthcare NHS Trust
2012-2014
Stoke Mandeville Hospital
2010-2013
Objectives : Resources for repair of cleft lip and palate may be lacking in low- middle-income countries. The Smile Train is a registered charity that supports resource-poor settings. In the global health care challenge, it has been suggested many babies born with palates are not repaired. This study aims to determine whether any variation exists proportion repairs undertaken Methods Data were obtained from database 352,191 consecutive operations performed between 2008 2011...
Approximately 45,000 women are diagnosed with breast cancer in the UK each year. The success of screening and introduction adjuvant therapies have meant that prognosis is improving an increasing number patients seeking reconstruction following mastectomy. purpose this study was to evaluate deep inferior epigastric perforator (DIEP) flap reconstructions performed Stoke Mandeville Hospital and, through analysis complications, detail evolution current care pathway.A retrospective all DIEP by...
The liver has long been recognized as having tolerogenic properties. We investigated whether recombinant adenoassociated virus (rAAV)-mediated expression of donor major histocompatibility complex in recipient livers could induce tolerance to donor-strain grafts.Naive B10.BR (H-2) or recipients primed with a H-2K-expressing (K) skin graft were injected rAAV-expressing H-2K (rAAV-K) K on hepatocytes 7 days before challenge graft. K-specific responses measured by interferon (IFN)-γ ELISpot and...
Abstract Background The use of sentinel lymph node biopsy (SLNB) in the older population, defined as those over 70 years old, has been debated since adoption SLNB into routine practice. Interestingly, there remains a paucity evidence, especially regarding rates positivity, complications, and subsequent adjuvant therapy with positivity. Method Data on patient's comorbidities, positivity rates, complication treatments were collected prospectively from 998 patients (644 < 354 ≥ old) between...
Following a High-Throughput Screening campaign to discover inhibitors of acid ceramidase, we report the novel and extremely potent covalent inhibitor,
The aim of this article is to provide an overview on paediatric facial paralysis, looking into aetiology, epidemiology, assessment and investigation subsequent treatment options available. Facial paralysis describes the inability activate muscles fascial expression. Overall, it affects 2.7 per 100 000 children under 10 years old 10.1 over each year. There are many causes outcomes necessary treatments vary depending cause. mainstays medical management corticosteroids therapy; however, when...
Metabolism is a tightly regulated sequence of events, supported by key reactions between enzymes and enzyme-specific substrates. These have the potential to produce metabolic side products that can deleterious effects further reactions. The nicotinamide repair system consists two partner enzymes, NAD(P)HX epimerase (NAXE) dehydratase (NAXD). regulate levels products. Here we present case an 11-month old child who presented our paediatric department with pyrexia, lethargy multiple cutaneous...
The first confirmed cases of SARS-CoV-2 cornovirus disease (COVID-19) in the UK were on 29th January 2020. On 23rd March, a UK-wide "stay at home" lockdown period commenced, restricting freedom movement an effort to mitigate viral spread and protect NHS resources. At time writing, has had over 300,000 COVID-19 with death toll 43,000 people.1Coronavirus Resource Centre. Johns Hopkins University. https://coronavirus.jhu.edu. [Accessibility verified June 26, 2020].Google Scholar Many hospitals...
Keloid scars are notoriously difficult to treat with very high recurrence rates despite a range of treatment options. We present case report 43-year-old man resistant keloid scar on his left ear from piercing. After 15 years multimodal treatments including surgery, steroid and 5-fluorourcil injections, the persisted. It has responded well single intralesional cryotherapy (trademark: CryoShape, Etgar Group International Ltd). The authors would now consider as useful tool in their...
Animal models have been used for many years in surgical research to develop different techniques, improve understanding of anatomy and physiology hone skills. The benefit such has particularly important developing relatively young specialties like plastic surgery techniques are designed studied animals long before they humans. We describe raising several reliable reproducible abdominal flaps rodents, including transverse rectus abdominis myocutaneous rats mice, superficial inferior...
In recent years, there has been an increasing interest in the practical applications of virtual reality (VR) healthcare. One discussed application this technology is to reduce anxiety during procedures for paediatric patients. Following skin loss patients, careful management wound with appropriate dressings and frequent dressing changes a key part treatment process. children, continued are often source anxiety, which complicates causing distress child, their parents staff members. VR systems...