A5020194366- Neonatal Respiratory Health Research
- Respiratory Support and Mechanisms
- Tracheal and airway disorders
- Congenital Diaphragmatic Hernia Studies
- Airway Management and Intubation Techniques
- Neuroscience of respiration and sleep
- Pneumonia and Respiratory Infections
- Congenital Heart Disease Studies
- Neonatal Health and Biochemistry
- Cardiac Arrest and Resuscitation
- Esophageal and GI Pathology
- Infant Development and Preterm Care
- Emergency and Acute Care Studies
- Streptococcal Infections and Treatments
- Neonatal and fetal brain pathology
- Mechanical Circulatory Support Devices
- Central Venous Catheters and Hemodialysis
- Infant Nutrition and Health
- Sepsis Diagnosis and Treatment
- Thermal Regulation in Medicine
- Neonatal and Maternal Infections
- Metabolism and Genetic Disorders
- Trauma and Emergency Care Studies
- Respiratory viral infections research
- Birth, Development, and Health
Taipei Veterans General Hospital
2016-2025
National Yang Ming Chiao Tung University
2016-2025
Chinese Medical Association
2021-2022
National Yang Ming University Hospital
1997-2021
Hungkuang University
2021
Sigma Theta Tau International
2020
Taipei Institute of Pathology
2018
Academy of Emergency Medicine and Care
1992-2009
Temple University
2001-2006
Alfred I. duPont Hospital for Children
2002-2006
Abstract Background Early antibiotic exposure may disrupt gut microbiome and affect the gut-lung axis. We examined impact of prolonged during early life on growth subsequent acute lung injury (ALI) in a rat pup model. Methods Thirty-four 7-day-old pups were divided into Control, Antibiotics (Anti), Lung (LI), Antibiotics-Lung Injury (Anti-LI) groups. The Anti Anti-LI groups received oral Amoxicillin-Clavulanic acid from 7 to 40 days old, while Control LI sham water. ALI was induced with...
Atopic dermatitis (AD) is one of the common allergic diseases in children. The presence was found to have association with risk developing attention-deficit hyperactivity disorder (ADHD) or autistic spectrum (ASD) children, but it still inconclusive. This study investigate longitudinal relationship between AD developed during toddlerhood and subsequent development ADHD ASD later childhood. Toddlers born 1998 2008 diagnosed at age younger than 3 years older 1 month were retrieved from...
Abstract Objective To evaluate the clinical role of flexible bronchoscopy (FB) in pediatric and neonatal intensive care units (ICUs). Design A retrospective review all patients receiving FB procedures between January 2005 December 2009. Setting Pediatric ICUs a tertiary multi‐disciplinary teaching hospital located northern Taiwan. Patients total 358 ICU (223 males) who received 725 procedures. Measurements Main Results The medical records were reviewed analyzed. Mean age for first time was...
Background The relationship between congenital heart disease (CHD) and malignancies has not been determined. This study aimed to explore the association of CHD with examine risk factors for development cancer after a diagnosis CHD. Patients Methods nationwide, population-based cohort on evaluated 31,961 patients newly diagnosed using Taiwan National Health Insurance Research Database (NHIRD) 1998 2006. standardized incidence ratios (SIRs) all specific types were analyzed, while Cox...
Background: The use of antibiotics in the early lives premature infants may alter microbiota and influence their clinical outcomes. However, whether administration probiotics can these outcomes remains unknown. In our study, were routinely administered unless contraindicated. We explored increased antibiotic exposure with routine was associated necrotizing enterocolitis (NEC) or bronchopulmonary dysplasia (BPD). Methods: A retrospective cohort study conducted, enrolling very low birth weight...
Acute fulminant cerebral edema in children following SARS-CoV-2 infection has been rarely reported. Such patients frequently demonstrate rapid progression and are usually fatal. In this retrospective study, we describe the detailed clinical, laboratory, neuroimaging features of six fatal cases Taiwan. All had shock initially, five showed to multiorgan failure disseminated intravascular coagulation, three developed acute respiratory distress syndromes. The inflammatory biomarkers first 3...
Hyperbilirubinemia is one of the most common causes for hospital admission in neonatal infants. Previous studies have found that jaundice may be initial symptoms related to urinary tract infection (UTI) This study evaluate incidence and factors infants with presentation hyperbilirubinemia final diagnosis UTI a tertiary teaching hospital.We retrospectively investigated medical records admitted younger than 8 weeks old between January December 2008. The jaundiced having tests urinalysis were...
Group B Streptococcus (GBS) infection is one of the major causes neonatal morbidity and mortality. Universal GBS screening with intrapartum antibiotic prophylaxis (IAP) in pregnant women were initiated 2012 Taiwan. This study aimed to analyze most recent maternal colonization rate changes from 2011 2016. All their live born neonates between January June 2016 retrospectively reviewed. Whether was done, results, presence risk factors, use antibiotics, outcome analyzed. In addition,...
Streptococcus agalactiae, or group B (GBS), remains to be one of the leading pathogens causing invasive infections in infants. The clinical GBS isolates from sterile sites patients younger than 18 years old were collected October 1998 December 2014 two hospitals Taiwan. Medical records retrospectively reviewed. Every isolate was serotyped with a multiplex PCR assay. Multilocus sequence typing (MLST) performed representative different serotypes. A total 205 181 182 infection episodes....
Background: Pediatric drug intoxication is a significant public health issue worldwide. The present study aimed to delineate the epidemiology, exposure-related conditions, and outcome severity of pediatric cases in Taiwan for over 36-year period. Methods: This retrospective cohort analyzed registered Taiwan’s National Poison Control Center (PCC) database between 1985 2020. Data on patient demographics, toxic substances, were extracted analyzed. Descriptive statistics used summarize findings....
Abstract This review article presents a comprehensive overview of the advancements in diagnosis and management pediatric acute respiratory distress syndrome (PARDS) as delineated Second Pediatric Acute Lung Injury Consensus Conference (PALICC-2) guidelines published 2023. The manuscript revisits initial definition (ARDS) nuanced distinctions between ARDS PARDS to provide foundational understanding. An approach algorithm for has been developed improve precision disease detection. Central...
Spirometry is a well-known technique for evaluating pulmonary function, but few studies have focused on preschool children. The aim of this study was to determine reference values forced spirometric parameters in young Chinese children, aged 3-6 years, Taiwan. Spirometric measurements were performed at day care centers by experienced pediatricians. Of 248 children without history chronic respiratory illness, least two valid attempts obtained from 214 (109 boys and 105 girls; age: 36-83 [mean...
Antibiotic resistance is a global problem, and the inappropriate overuse of antibiotics major cause. Among children seeking medical help, acute respiratory tract infections (ARTIs) are most common tentative diagnosis made by physicians leading condition for which prescribed. This study aimed to examine trends prescribing in pediatric ambulatory care Taiwan over 10-year period.Children younger than 18 years old being diagnosed as having ARTIs [International Classification Diseases, Ninth...
BackgroundDue to the increase of breastfeeding in infants, iron deficiency anemia (IDA) related prolonged, predominant should be concern. Mostly, manifestation IDA is indistinguishable and enthusiastic advocacy without concomitant education complementary food may lead ignorance breast milk-related IDA, which result impaired psychomotor development baby. This retrospective study was conducted re-emphasize this easily ignored but still prevalent illness.MethodsThis involved 15 babies who were...
Background The mortality risk associated with congenital airway anomalies (CAA) in children heart disease (CHD) is unclear. This study aimed to investigate the factors CAA, and risk, among CHD. Methods nationwide, population-based evaluated 39,652 CHD aged 0–5 years between 2000 2011, using Taiwan National Health Insurance Research Database (NHIRD). We performed descriptive, logistic regression, Kaplan–Meier, Cox regression analyses of data. Results Among CHD, 1,591 (4.0%) had concomitant...
The early detection and prediction of bacteremic sepsis in preterm term neonates remains a challenging task because their nonspecific clinical presentations. We aimed to investigate the risk factors associated with bacteremia find cutoff values predictive markers achieve accurate diagnosis neonatal sepsis.Not-doing-well suspected were retrospectively enrolled between January 2015 December 2017 Taipei Veterans General Hospital. Blood culture, hemogram, serum procalcitonin (PCT), C-reactive...
Esophageal atresia (EA), tracheoesophageal fistula (TEF), or both is a complicated problem. The purpose of this study was to evaluate the outcomes and postoperative complications in patients with EA/TEF who were admitted our hospital.In total, 15 enrolled from 1994 2003, including 8 males 7 females. Patient demographics, associated anomalies, analyzed.The most common variant EA distal TEF (type C), which occurred 12 (80%). latter had congenital cardiac anomalies frequent, occurring (53.3%)....