A5075601805- Tracheal and airway disorders
- Respiratory Support and Mechanisms
- Obstructive Sleep Apnea Research
- Airway Management and Intubation Techniques
- Neuroscience of respiration and sleep
- Ear and Head Tumors
- Cleft Lip and Palate Research
- Medical Coding and Health Information
- Vascular Malformations and Hemangiomas
- Artificial Intelligence in Healthcare
- Cardiac, Anesthesia and Surgical Outcomes
- Dysphagia Assessment and Management
- Pediatric Pain Management Techniques
- Voice and Speech Disorders
- Machine Learning in Healthcare
Queensland Children’s Hospital
2019-2024
The University of Queensland
2023
Mater Misericordiae Hospital
2023
Children’s Health Queensland Hospital and Health Service
2019
Anti-carbohydrate antibodies (Abs) play crucial roles in pathogen control, but their generation remains poorly understood. By studying responses to Streptococcus pyogenes humans, we reveal that the glycan-targeted response shifts from IgM towards IgG and IgA memory with age antigen exposure across blood, spleen, tonsils. Both natural colonization controlled human infection S. increased class-switched B cells, evidence of within-clone switching. Glycan-specific cells readily participated...
To determine the incidence, outcomes, and evaluate diagnostic modalities for postoperative vocal cord dysfunction (VCD) following cardiothoracic surgery in children.A prospective mixed-methods study using principles of implementation science was completed. All patients undergoing involving aortic arch, ductus, or ligamentum arteriosum vascular rings from September 2019 to December 2020 were enrolled. Patients underwent speech pathology assessment, laryngeal ultrasound, flexible direct...
The clinical prioritisation criteria (CPC) are a decision support tool that ensures patients referred for public specialist outpatient services to Queensland Health assessed according their urgency. Medical referrals manually triaged and prioritised into three categories by the associated health service before appointments booked. We have developed method using artificial intelligence automate process of categorizing medical based on prioritization guidelines. Using machine learning...
Hypoxaemia during anaesthesia for tubeless upper airway surgery in children with abnormal airways is common due to the complexity of balancing adequate depth maintenance spontaneous breathing and providing an uninterrupted field view surgeon. High-flow nasal oxygenation (HIGH-FLOW) can prolong safe apnoea time be used but date has not been compared alternative technique low-flow (LOW-FLOW). The aim investigate if use HIGH-FLOW reduce number hypoxaemic events requiring rescue LOW-FLOW....
Aim Tonsillectomy procedures are a core element of paediatrics; however, perioperative management differs. This study aimed to describe tonsillectomy management, including the burden pain, nausea and delayed recovery. Methods A prospective cohort was undertaken through an audit practice recovery survey interviews with family members 7–14 days post‐surgery. The at Australian tertiary referral paediatric hospital between June September 2016. Results included 255 children undergoing...
Pyogenic granulomas are benign vascular lesions occurring on skin and mucous membranes, most commonly in the oral cavity. A case report of a woman her 80s who presented with one episode haemoptysis, secondary to an atypical epiglottic lesion is discussed. The patient denied associated symptoms, such as dyspnoea, dysphasia or recent weight loss. Flexible nasendoscopy CT scan confirmed highly pedunculated mass left laryngeal surface epiglottis. was completely excised there no sign recurrence...
Background: Tubeless upper airway surgery in children is a complex procedure where surgeons and anaesthetists share the same operating field. These procedures are often interrupted for rescue oxygenation. The efficacy of nasal high-flow oxygenation to decrease frequency interruptions undergoing unknown.Methods: In this multicentre randomised trial conducted 5 tertiary hospitals Australia, aged 0-16 years age requiring tubeless were (1:1) receive either or standard-care during surgery. oxygen...
Abstract Obstructive sleep apnoea (OSA) is a common problem in children, and can result developmental cognitive complications if untreated. The gold-standard tool for diagnosis polysomnography (PSG); however, it an expensive time-consuming test to undertake. Overnight oximetry has been suggested as faster cheaper alternative PSG be performed at home using limited, reusable equipment. This study aims evaluate the effectiveness of service (implemented response extended waiting times routine...