Summary Background Microneedle fractional radiofrequency has been reported to be effective for improving wrinkles, enlarged pores and various scars. Sublative shown induce both ablation of epidermis upper dermal remodelling, which had rejuvenation effects in photoaged skin. Both modalities may have the potential synergy improve acne Objective To evaluate efficacy safety combined microneedle sublative scars Asian Methods Twenty subjects comprised 11 males 9 females (mean age 23.65 ± 2.94,...

Recent studies suggest that dipeptidyl peptidase 4 (DPP-4) inhibitors are associated with an increased risk of developing bullous pemphigoid (BP). Population-based on the association between DPP-4 and BP limited.To characterize potential use BP.This retrospective, nationwide, population-based, case-control study using Korean insurance claims data from January 1, 2012, to December 31, 2016, included patients newly diagnosed diabetes. Control diabetes (and without BP) were randomly obtained...

ABSTRACT BACKGROUND AND PURPOSE We present the nerve ultrasound findings in chronic inflammatory demyelinating polyneuropathy (CIDP) and examine their correlation with electrophysiology functional disability. METHODS A total of 75 healthy controls 48 CIDP patients underwent clinical, sonographic electrophysiological evaluation a mean 3.9 years(SD+/−2.7) after disease onset. RESULTS Nerve revealed statistically significant higher cross‐sectional area (CSA) values median ( P <.0001), ulnar...

Statement of Retraction We, the Editors and Publisher Journal Cosmetic Laster Therapy, have retracted following article: Kyu Young Seo, Dong Hyun Kim, Sang Eun Lee, Moon Soo Yoon & Hee Jung Lee (2013) Skin rejuvenation by microneedle fractional radiofrequency a human stem cell conditioned medium in Asian skin: randomized controlled investigator blinded split-face study, Laser 15:1, 25-33, https://doi.org/10.3109/14764172.2012.748201 Since publication, concerns been raised about originality...

Abstract Background For skin rejuvenation, microneedle fractional radiofrequency (RF) is a recently developed minimally invasive method for delivering RF energy directly into the using microneedle. Objective We evaluated efficacy and safety of rejuvenation in Asian also conducted immunohistochemical analysis before after treatment. Patients Methods Twenty‐five females (mean age 54.2, Fitzpatrick phototypes III–IV) received three consecutive treatment at 4‐week intervals. Outcome assessments...

This study investigated the utility of pain-related evoked potentials (PREP's) elicited by a nociceptive electrical stimulation skin (= electrically potentials) in early detection diabetic small-fiber neuropathy.We studied 36 'young' (19-35 years) and 24 'older' (36-65 healthy subjects as well 35 patients (35-64 with diabetes neuropathic symptoms 22 (34-64 without symptoms. Only normal standard nerve conduction testing were included.In symptoms, we found significant increase PREP latencies...

Background.—To develop a German language questionnaire for screening migraine, tension‐type headache, and trigeminal autonomic cephalgias. Objective.—Aim of the study was to self‐administered headache migraine (MIG), (TTH), trigeminal‐autonomic cephalgias (TAC). Methods.—Questionnaire‐based diagnoses were blindly compared with those experts. Results.—Overall 278 patients (MIG = 97, TTH 60, TAC 98, MIG plus 23) as well 42 low back pain without 47 healthy subjects studied. The Cohen's kappa 7...

A minimally invasive fractional radiofrequency microneedle (FRM) device has been used in skin rejuvenation and acne scars, a recent pilot study demonstrated the positive therapeutic effect on acne. We evaluated efficacy of FRM for vulgaris Asians conducted objective measurement to assess its sebum production.Twenty Korean patients with received single full-face treatment. Outcome assessments included standardized photography, physician's global assessment, patient's satisfaction scores,...

Postherpetic neuralgia (PHN) is a sequela of herpes zoster that adversely affects quality life seriously. The risk factors for PHN are well known but the effective interventions reduce incidence less studied. objective this study to evaluate efficacy treatment with gabapentin in patients acute preventing PHN. We performed prospective randomized controlled 120 participants diagnosed zoster, aged 50 and over complaining moderate severe pain. All were treated valacyclovir acetaminophen. Half...

AbstractBackground: Intense focused ultrasound (IFUS) has been used successfully for skin tightening.Objective: To investigate the efficacy of IFUS in treating enlarged pores and to evaluate changes elasticity sebum production following IFUS.Materials methods: Twenty-two subjects with were randomized receive a single treatment using 1.5-mm transducer on one side face, 3.0-mm other. Objective clinical assessments made by blinded photographic evaluation. Subjective satisfaction adverse effects...

Hyaluronic acid (HA)-based microneedle patch has recently been studied for wrinkle improvement. Cross-linked HA (CLHA) is widely used in dermal fillers. Acetyl hexapeptide-8 (AHP-8) and epidermal growth factor (EGF) are cosmetic ingredients.This study aimed to verify the efficacy of CLHA/HA-based with microstructure (microneedle patch) containing AHP-8 or EGF.A total 52 Korean females were enrolled a double-blind, randomized, controlled, split-face trial. The subjects divided into 3 groups:...

Primary inoculation tuberculosis results from the direct of Mycobacterium into skin a person who has no natural or artificially acquired immunity to organism. The pathogenesis requires break in an abrasion injury that allows entry tubercle bacilli. We report 3 cases primary resulting illegal acupuncture. Three patients over 70 years old presented with erythematous, ulcerative, indurated plaques on back. Skin lesions had developed at acupuncture sites 1 2 weeks after session acupuncture,...

Abstract Plate‐like osteoma cutis ( PLOC ) is a dermatological disorder characterized by superficial ossification and rarely occurs without any underlying tissue abnormalities or pre‐existing calcification. The hereditary form of mainly due to inactivating mutation in the GNAS gene. Inactivating gene associated with several diseases, which commonly manifest heterotopic hormonal resistance; however, development malignant neoplasm has never been reported. Herein, we report case patient novel...

Background and Objective Skin aging results in physiological alterations keratinocyte activities epidermal function, as well dermal changes. Yet, the cellular molecular mechanisms that cause dysfunction during skin are not understood. Recently, role of hyaluronan (HA) an active regulator dynamic processes is getting attention HA metabolism thought to be important age‐related dysfunction. Microneedle fractional radiofrequency (RF) has shown effects for improving cutaneous aging. However,...

Congenital syphilis occurs when Treponema pallidum crosses the placenta during pregnancy or from contact with an infectious genital lesion delivery. Cutaneous manifestations of congenital are relatively common, occurring in approximately 30% to 70% patients. Maculopapular lesions, vesiculobullous condylomata lata annular and erythema multiforme-like targetoid lesions have been reported. We report on a premature newborn who presented generalized bullous pustular eruption desquamation at birth.

Background An objective measurement of scar is important for evaluating treatment outcomes. However, to date, there no ‘gold standard’ quantitative properties hypertrophic scar. Existing modalities are neither portable nor easy use. Objective This study aims validate the correlation between measurements with SkinFibrometer ® , SkinGlossMeter and Mexameter subjective assessment Vancouver Scar Scale ( VSS ) keloid Methods A total 25 patients keloids scars were enrolled in this study. Patients...

Abstract Bowen's disease ( BD ) usually occurs on sun‐exposed areas in elderly patients. rarely childhood and lesions of the nail unit periungual area are likely associated with human papillomavirus infection. Herein, we report a case presenting 12‐year‐old boy which was successfully treated two sessions photodynamic therapy.

Abstract Background: Although the pattern of cancer incidence in South Korea is not same as that western countries, urological will become one major cancers near future. The becoming steadily similar to countries. It is, therefore, important understand epidemiological features cancer. Surveillance and mortality trends provides clues etiology helps assess effects improved diagnostic, screening intervention measures. Methods: subjects study were 13 208 patients living Korea, newly diagnosed...

Objective To describe an indwelling urethral catheter coated with gentamicin sulphate on the inner and outer surface of catheter, to evaluate efficacy safety this in preventing catheter‐associated infections rabbits. Materials methods Sixty rabbits were divided equally into control experimental groups which then subdivided according duration catheterization (1, 3 5 days). Silicone‐treated latex catheters used group gentamicin‐releasing group. Urine samples swabs from cultured for...