A5052921134- Education and Learning Interventions
- Cerebral Palsy and Movement Disorders
- Tendon Structure and Treatment
- Educational Systems and Policies
- Neonatal and fetal brain pathology
- Diverse Approaches in Healthcare and Education Studies
- Musculoskeletal pain and rehabilitation
- Shoulder Injury and Treatment
- Dysphagia Assessment and Management
- Spine and Intervertebral Disc Pathology
- Educational Research and Pedagogy
- Semiconductor materials and devices
- Psychosocial Factors Impacting Youth
- Sports injuries and prevention
- Tracheal and airway disorders
- Mitochondrial Function and Pathology
- Consumer Perception and Purchasing Behavior
- Esophageal and GI Pathology
- Nerve Injury and Rehabilitation
- Myofascial pain diagnosis and treatment
- Hip and Femur Fractures
- Education, Safety, and Science Studies
- Orthopedic Surgery and Rehabilitation
- Botulinum Toxin and Related Neurological Disorders
- Diverse Topics in Contemporary Research
CHA Bundang Medical Center
2015-2025
CHA University
2015-2025
SK Group (South Korea)
2022-2023
Bridge University
2022
Yonsei University
2021
Severance Hospital
2021
JSR (Japan)
2015
Eulji University
2014
Samsung (South Korea)
2010
Korea University
2007
Allogeneic umbilical cord blood (UCB) has therapeutic potential for cerebral palsy (CP). Concomitant administration of recombinant human erythropoietin (rhEPO) may boost the efficacy UCB, as it neurotrophic effects. The objectives this study were to assess safety and allogeneic UCB potentiated with rhEPO in children CP. Children CP randomly assigned one three parallel groups: pUCB group, which received rhEPO; EPO placebo UCB; Control rhEPO. All participants rehabilitation therapy. main...
Tendinopathy is a common musculoskeletal condition causing pain and dysfunction. Conventional treatment surgical procedures for tendinopathy are insufficient; accordingly, recent research has focused on tendon-healing regenerative approaches. Tendon injuries usually occur in the hypoxic critical zone, characterized by increased oxidative stress mitochondrial dysfunction; thus, exogenous intact mitochondria may be therapeutic. We aimed to assess whether transplantation could induce...
Objective The incidence of hip fractures is increasing worldwide with the aging population, causing a challenge to healthcare systems due associated morbidities and high risk mortality. After in frail geriatric patients, existing comorbidities worsen new complications are prone occur. Comprehensive rehabilitation essential for promoting physical function recovery minimizing complications, which can be achieved through multidisciplinary approach. Recommendations required assist providers...
This study evaluated the efficacy of umbilical cord blood (UCB) cell for patients with cerebral palsy (CP) in a randomized, placebo-controlled, double-blind trial and also assessed factors mechanisms related to efficacy. Thirty-six children (ages 6 months 20 years old) CP were enrolled treated UCB or placebo. Muscle strength gross motor function at baseline 1, 3, after treatment. Along measurements, each subject underwent 18F-fluorodeoxyglucose positron emission tomography 2 weeks Cytokine...
3D ferroelectric NAND (Fe-NAND) Quad-level cell (QLC) operation has been demonstrated for the first time to our knowledge, using CTN test vehicle mass production. The Fe-NAND is optimized by engineering stack layers, enlarging a program/erase (PE) window up 10.5 V. QLC successfully verified with minimum gap margin of 0.24 Endurance and data retention characteristics are also reported.
Dysphagia is a common clinical condition characterized by difficulty in swallowing. It sub-classified into oropharyngeal dysphagia, which refers to problems the mouth and pharynx, esophageal body esophagogastric junction. can have significant negative impact one's physical health quality of life as its severity increases. Therefore, proper assessment management dysphagia are critical for improving swallowing function preventing complications. Thus guideline was developed provide...
The purpose of this study was to define the acoustic voice and speech characteristics patients with Parkinson disease (PD). Seven female PD seven healthy controls participated in study. Each subject instructed
To compare quantitative muscle activation between erect and slouched sitting postures in the muscles around scapula, to investigate correlation angle of thoracic kyphosis alteration activity depending on two different postures.Ten healthy males participated study. Unilateral surface electromyography (SEMG) was performed for serratus anterior, middle trapezius (MT), lower (LT), which are scapular stabilizer muscles, as well latissimus dorsi. Participants elevated their shoulders 3 seconds up...
Tendinopathy is a term used to describe tendon disorders that are marked by pain and loss of function. Recent studies demonstrated inflammation plays an important role throughout the broad spectrum tendinopathy. Conventional treatments such as steroid injections, analgesics, physical modalities simply give relief do not alter disease progression without regeneration effect. Tenocytes responsible for maintaining matrix understanding how they function essential studying new Our previous study...
Concomitant administration of allogeneic umbilical cord blood (UCB) infusion and erythropoietin (EPO) showed therapeutic efficacy in children with cerebral palsy (CP). However, no clinical studies have investigated the effects UCB EPO combination therapy using a 2 × four-arm factorial blinded design four arms. This randomized placebo-controlled trial aimed to identify synergistic individual efficacies cell for treatment CP.Children diagnosed CP were randomly segregated into groups: (A)...
An in vitro culture period of at least 2 weeks is required to produce sufficient natural killer (NK) cells for immunotherapy, which are the key effectors hematological malignancy treatment. Mitochondrial damage and fragmentation reduce NK cell immune surveillance capacity. Thus, we hypothesized that transfer healthy mitochondria could enhance their anticancer effects. Allogeneic isolated from WRL-68 were transferred cells. We evaluated cells' proliferative capacity, cycle, cytotoxic capacity...
Background: A nationwide Rehabilitation at Home Care Pilot Program for patients undergoing lower extremity orthopedic surgeries has been ongoing since 2020.The program was designed to improve clinical outcomes through early mobilization and rehabilitation after discharge.This study aimed analyze the interim data assess its effectiveness suggest improvements, particularly older who are more vulnerable compared younger patients.Methods: We analyzed of 872 from seven hospitals.Patients were...
Postherpetic neuralgia (PHN) is a sequela of herpes zoster that adversely affects quality life seriously. The risk factors for PHN are well known but the effective interventions reduce incidence less studied. objective this study to evaluate efficacy treatment with gabapentin in patients acute preventing PHN. We performed prospective randomized controlled 120 participants diagnosed zoster, aged 50 and over complaining moderate severe pain. All were treated valacyclovir acetaminophen. Half...
The objective of this study was to identify the differences in medication effect according pain characteristics spinal cord-injured patients.This is a prospective, randomized, crossover study. Fifty-five patients and 66 locations neuropathic were included. Pain classified into four spontaneous three evoked characteristics. Oxcarbazepine (Na channel blocker) pregabalin (calcium α2-δ ligand medication) tried. Patients divided two groups: present absent. Overall average visual analog scale...
To observe changes in pharyngeal pressure during the swallowing process according to postures normal individuals using high-resolution manometry (HRM).Ten healthy volunteers drank 5 mL of water twice while sitting a neutral posture. Thereafter, they same amount head rotation and tilting postures. The time deglutition for each posture were measured with HRM. data obtained these two compared those from posture.The maximum pressure, area, rise time, duration velopharynx (VP) tongue base (TB)...
In this study, we demonstrate for the first time multi-level capable 3D ferroelectricNAND (Fe-NAND) device using NAND test vehicle mass production. The present ferroelectric shows potential cell operation with 3.4 V program/erase window. We also reported cycling and retention characteristics.
A highly manufacturable multi-level NAND flash memory with a 27nm design rule has been successfully developed for the first time. Its unit cell size is 0.00375um <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> (with overhead). Self Aligned Reverse Patterning used to improve initial Vth distribution induced from DPT (Double Technology) process. By using advanced channel doping technique, junction leakage minimized and Vpass window...
ABSTRACT Vitamin D (Vit D) increases calcium absorption in the intestine after binding to Vit receptor (VDR). The VDR has also been identified muscle cells. supplementation resulted improved strength. However, there is a paucity of studies role on tenocytes. We investigated effects damaged Human tenocytes were treated with dexamethasone (Dex) induce cell injury. Expression tenocyte‐related markers tenomodulin (Tnmd), tenascin C (Tnc), scleraxis (Scx), mohawk (Mkx), and collagen (Col) 1 3...
There is no evidence that one exercise program better than another for rehabilitation of patients with chronic low back pain (CLBP).To identify the safety and efficacy a gradable stabilization protocol in CLBP.This study retrospective cohort 65 patients. The group received 3 weeks over 6-8 visits, while control did not receive any protocol. All subjects were evaluated visual analog scale (VAS), Oswestry Disability Index (ODI), Fear-Avoidance Belief Questionnaire (FABQ), active sit-up test...
To investigate the predictive value of enhanced-magnetic resonance imaging (MRI) and fluoroscopic factors regarding effects transforaminal epidural steroid injections (TFESIs) in low back pain (LBP) patients with lumbosacral radiating pain.A total 51 who had LBP were recruited between January 2011 December 2012. The patient data classified into two groups 'favorable group' 'non-favorable after 2 weeks follow-up results. favorable group was defined as those a 50%, or more, reduction severity...
Umbilical cord-mesenchymal stem cell-conditioned medium (UC-MSC-CM) has emerged as a promising cell-free therapy. The aim of this study was to explore the therapeutic effects UC-MSC-CM on insulin resistance in C2C12 cell. Insulin induced by palmitate. Effects were evaluated using glucose uptake, transporter type 4 (GLUT4) translocation, insulin-signaling pathway, and mitochondrial contents functions Glucose uptake improved UC-MSC-CM. treatment increased only membranous GLUT4 expression, not...