Dong Keun Han

ORCID: 0000-0003-4641-7883
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About
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Research Areas
  • Electrospun Nanofibers in Biomedical Applications
  • Bone Tissue Engineering Materials
  • Polymer Surface Interaction Studies
  • biodegradable polymer synthesis and properties
  • Tissue Engineering and Regenerative Medicine
  • Coronary Interventions and Diagnostics
  • 3D Printing in Biomedical Research
  • Osteoarthritis Treatment and Mechanisms
  • Mesenchymal stem cell research
  • Nanoparticle-Based Drug Delivery
  • Graphene and Nanomaterials Applications
  • Extracellular vesicles in disease
  • Hydrogels: synthesis, properties, applications
  • Silk-based biomaterials and applications
  • Nanoplatforms for cancer theranostics
  • Periodontal Regeneration and Treatments
  • Advanced Polymer Synthesis and Characterization
  • RNA Interference and Gene Delivery
  • MicroRNA in disease regulation
  • Orthopaedic implants and arthroplasty
  • Photopolymerization techniques and applications
  • Surgical Sutures and Adhesives
  • Photochromic and Fluorescence Chemistry
  • Dental materials and restorations
  • Peripheral Artery Disease Management

CHA University
2017-2025

Beijing University of Technology
2024

Sungkyunkwan University
2003-2023

University of Virginia Health System
2023

Tokyo Institute of Technology
2023

CHA Bundang Medical Center
2023

Kangwon National University
2023

Kyungpook National University
2023

Gyeonggi Research Institute
2021

Seonam University
2019-2020

Hydrogel systems based on cross-linked polymeric materials which could provide both adhesion and cohesion in wet environment have been considered as a promising formulation of tissue adhesives. Inspired by marine mussel adhesion, many researchers tried to exploit the 3,4-dihydroxyphenylalanine (DOPA) molecule cross-linking mediator synthetic polymer-based hydrogels is known be able achieve cohesive hardening well adhesive bonding with diverse surfaces. Beside DOPA residue, composition other...

10.1021/bm4017308 article EN Biomacromolecules 2014-03-20

Capture and release: The material-independent surface chemistry of a poly(norepinephrine) (pNE) which exhibits perfect smoothness at the nanometer scale is controlled by 3,4-dihydroxybenzaldehyde-norepinephrine (DHBA-NE) conjugates. pNE layer containing DHBA-NE serves to store release small therapeutics such as nitric oxide. As service our authors readers, this journal provides supporting information supplied authors. Such materials are peer reviewed may be re-organized for online delivery,...

10.1002/anie.201301646 article EN Angewandte Chemie International Edition 2013-07-10

Abstract Biodegradable polymers, such as poly(glycolic acid) (PGA), poly(L-lactic (PLLA) and poly(lactic-co-glycolic (PLGA), were dissolved individually in the proper solvents then subjected to electrospinning process make nanofibrous scaffolds. Their surfaces chemically modified using oxygen plasma treatment situ grafting of hydrophilic acrylic acid (AA). The fiber thickness, pore size porosity estimated 200–800 nm, 2–30 μm 94–96%, respectively, these properties insignificant PGA, PLLA PLGA...

10.1163/156856207780424997 article EN Journal of Biomaterials Science Polymer Edition 2007-01-01

10.1016/j.progpolymsci.2014.10.004 article EN Progress in Polymer Science 2014-10-30

Exosomes derived from mesenchymal stem cells (MSCs) have been studied as vital components of regenerative medicine. Typically, various isolation methods exosomes cell culture medium developed to increase the yield exosomes. Moreover, exosome-depletion process serum has considered result in clinically active and highly purified medium. Our aim was compare methods, ultracentrifuge (UC)-based conventional method, tangential flow filtration (TFF) system-based method for separation with high...

10.1177/20417314211008626 article EN cc-by-nc Journal of Tissue Engineering 2021-01-01

Nanocomplex immobilized scaffold effects on anti-inflammation, antibacterial activity, angiogenesis, and bone regeneration.

10.1126/sciadv.abj1083 article EN cc-by-nc Science Advances 2021-12-08

New lactide-based poly(ethylene glycol) (PEG) polymer networks (GL−PEGs) have been prepared by UV photopolymerization using two nontoxic macromers, triacrylated lactic acid oligomer emanating from a glycerol center (GL) and monoacrylated PEG. These materials developed for use as scaffolds in tissue engineering, which cell-adhesion resistant, ligand-immobilizable, biodegradable characteristics. The GL−PEG cross-linked obtained were glassy transparent, the gel content was approximately 90%,...

10.1021/ma970302u article EN Macromolecules 1997-10-01

Surfaces of commercial polyurethanes (PUs) were modified by poly(ethylene oxide) (PEO) grafting and/or heparin immobilization for long-term biomedical applications. PU surfaces treated with diisocyanate and then reacted PEO or heparin. The immobilized various methods on the surface was very stable, concentrations 1.45–1.84 m̈g/cm2. Surface structure characteristics each examined performing following analyses: attenuated total reflection infrared (ATR-IR), electron spectroscopy chemical...

10.1002/jbm.820231309 article EN Journal of Biomedical Materials Research 1989-04-01

Cadmium is known to exert toxic effects on multiple organs, including the testes. To determine if alpha-tocopherol, an antioxidant, could protect testicular tissues and spermatogenesis from of cadmium, six-week old male Sprague-Dawley rats were randomized receive cadmium at doses 0 (control), 1, 2, 4 or 8 mg/kg by intraperitoneal route (Group A) alpha-tocopherol for 5 days before being challenged with B) in identical dose-dependent manner. When both groups received 1 mg/kg, there no changes...

10.3346/jkms.2006.21.3.445 article EN Journal of Korean Medical Science 2006-01-01

Regenerative medicine, one of the most exciting and dynamic life science fields, is an emerging biomedical technology for assisting accelerating regeneration repair lost or damaged organs body parts. Modern regenerative medicine increasingly using three-dimensional structured scaffolds because they represent a wide range morphological geometric in vivo possibilities that can be tailored each specific application. This review focuses on polymeric scaffolds, highly promising strategy,...

10.1080/15583724.2010.537800 article EN Polymer Reviews 2011-01-13
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