- Glycosylation and Glycoproteins Research
- Soybean genetics and cultivation
- Polymer Surface Interaction Studies
- Agriculture, Soil, Plant Science
- Advanced Biosensing Techniques and Applications
- Monoclonal and Polyclonal Antibodies Research
- Legume Nitrogen Fixing Symbiosis
- Viral Infectious Diseases and Gene Expression in Insects
- Nanofabrication and Lithography Techniques
- Food Quality and Safety Studies
- Bone Tissue Engineering Materials
- Advanced biosensing and bioanalysis techniques
- Carbohydrate Chemistry and Synthesis
- Vibrio bacteria research studies
- Bacteriophages and microbial interactions
- Biosensors and Analytical Detection
- Electrospun Nanofibers in Biomedical Applications
- Nanoparticle-Based Drug Delivery
- Bacterial Genetics and Biotechnology
- Silk-based biomaterials and applications
- Protein purification and stability
- 3D Printing in Biomedical Research
- Microbial Metabolites in Food Biotechnology
- Enzyme Catalysis and Immobilization
- Agronomic Practices and Intercropping Systems
Yeungnam University
2016-2025
Rural Development Administration
2019-2024
Wonkwang University
2024
Korea Pharma (South Korea)
2024
Eulji University
2023
Eulji University Hospital
2023
RELX Group (Netherlands)
2023
Institute of Crop Science
2021
Chungbuk National University
2021
Pohang University of Science and Technology
2007-2016
Hydrogel systems based on cross-linked polymeric materials which could provide both adhesion and cohesion in wet environment have been considered as a promising formulation of tissue adhesives. Inspired by marine mussel adhesion, many researchers tried to exploit the 3,4-dihydroxyphenylalanine (DOPA) molecule cross-linking mediator synthetic polymer-based hydrogels is known be able achieve cohesive hardening well adhesive bonding with diverse surfaces. Beside DOPA residue, composition other...
During implant surgeries, antibacterial agents are needed to prevent bacterial infections, which can cause the formation of biofilms between implanted materials and tissue. Mussel adhesive proteins (MAPs) derived from marine mussels bioadhesives that show strong adhesion coating ability on various surfaces even in wet environment. Here, we proposed a novel surface-independent strategy based fusion MAP silver-binding peptide, synthesize silver nanoparticles having broad activity. This sticky...
The solubility of commonly used anti-inflammatory drugs has become a significant concern in contemporary medicine. Furthermore, inflammatory arthritis stands out as the most prevalent chronic disease globally. disease's pathology is characterized by heightened inflammation and oxidative stress, culminating pain loss joint functionality. Fenofibric acid (FFA) exhibits notable potential. This research assesses effects FFA, both its standalone form inclusion complexes (ICs) with β-cyclodextrin...
We found the expression of neurofilament was very low in undifferentiated human adult bone marrow mesenchymal stem cells (hMSCs), but its could be significantly induced after treatment with combination growth factors. Approximately 16% hMSCs differentiated into expressing a FGF and RA, retinoic acid. also examined effect five different cell culture substrates on neurofilament. One specific that particularly effective provoking pre-neuronal differentiation culturing fibronectin-coated dishes...
Here, we report on the development and characterization of a carbonic anhydrase (CA)-based biocatalyst encapsulated in biosilica matrix for use environmental CO2 sequestration. Encapsulation occurred simultaneously with autonomous silica synthesis by silica-condensing R5 peptide that was fused to recombinant CA. The encapsulation efficiency greater than 95%, CA not leached from matrix, demonstrating highly efficient R5-mediated autoencapsulation process. catalytic efficiencies both esterase...
ABSTRACT Carbonic anhydrase is an enzyme that reversibly catalyzes the hydration of carbon dioxide (CO 2 ). It has been suggested recently this remarkably fast can be used for sequestration CO , a major greenhouse gas, making promising alternative chemical mitigation. To promote economical use enzymes, we engineered carbonic from Neisseria gonorrhoeae ( ng CA) in periplasm Escherichia coli thereby creating bacterial whole-cell catalyst. We then investigated application system to by mineral...
Effective surface immobilization is a prerequisite for numerous carbohydrate-related studies including carbohydrate–biomolecule interactions. In the present work, we report simple and rapid modification technique diverse carbohydrate types in which direct oriented onto gold accomplished by coupling amine group of thiol group-bearing aminophenyl disulfide as new reagent with an aldehyde terminal reducing sugar carbohydrate. To demonstrate generality this proposed reductive amination method,...
Complex coacervation is a liquid-liquid phase separation in colloidal system of two oppositely charged polyelectrolytes or colloids. The interfacial tension the coacervate key parameter for micelle formation and interactions with encapsulating material. However, relationship between tensions various salt solutions poorly understood complex coacervation. In present work, dynamics recombinant mussel adhesive protein (MAP) hyaluronic acid (HA) were determined presence Hofmeister series ions....
Unique adhesive and biocompatibility properties of mussel proteins (MAPs) are known for their great potential in many tissue engineering biomedical applications. Previously, it was successfully demonstrated that redesigned hybrid type MAP, fp-151, mass-produced Gram-negative bacterium Escherichia coli, could be utilized as a promising biomaterial. However, purification recombinant fp-151 has been unsatisfactory due to its nature polarity which make separation contaminants (especially,...
Silk has recently been exploited in various fields due to its superior mechanical properties. However, this material's lack of biological functions and relatively poor biodegradation have hindered wide use applications related cells tissues. Here, we improved the overall characteristics silkworm silk fibroin (SF) by introduction RGD peptide-fused recombinant mussel adhesive protein (MAP-RGD). Simple blending MAP-RGD provided not only bulk-scale ability but also microscale adhesiveness...
Relaxivity tuning of nanomaterials with the intrinsic T1- T2 dual-contrast ability has great potential for MRI applications. Until now, relaxivity T1 and dual-modal nanoprobes been accomplished through dopant, size, morphology nanoprobes, leaving room bioapplications. However, a surface engineering method was seldom reported. Here, we report novel based on dual-mode (DMNPs), along protein interaction monitoring DMNPs as biosensor application. Core nanoparticles (NPs) europium-doped iron...
ABSTRACT Several fusion strategies have been developed for the expression and purification of small antimicrobial peptides (AMPs) in recombinant bacterial systems. However, some these efforts limited by product toxicity to host cells, proteolysis, low levels, poor recovery yields, sometimes an absence posttranslational modifications required biological activity. For present work, we investigated use baculoviral polyhedrin (Polh) protein as a novel partner production model AMP (halocidin...
Abstract Mussel adhesive protein (MAP) type 3 (fp-3) is considered one of the key components for mussel adhesion. However, its bulk strength has not been characterized due to availability in limited quantities. In present work, a feasible production (∼47 mg l−1) recombinant fp-3 was achieved, and measured first time; ∼0.57 MPa unmodified form ∼0.94 ∼2.28 3,4-dihydroxy-L-phenylalanine (DOPA)-modified form, having 9.6% yield without with oxidant treatment, respectively. Furthermore, values...
Phytophthora root and stem rot (PRSR), an infection caused by sojae in soybean [ Glycine max (L.) Merr.], is important threat to production South Korea; however, the precise genetic mechanisms related PRSR resistance remain largely unclear, limiting development of resistant cultivars. This study aimed identify candidate ( R ) genes soybeans through a genome-wide association (GWAS). We evaluated 205 accessions inoculated with P. isolates GJ3053 or AD3617 using hypocotyl inoculation method...
A method for capture and release of cells was developed using a photolabile linker antibody-attached glass surface with poly(ethylene glycol) (PEG)-pattern.