A5004939754- Lichen and fungal ecology
- Biochemical Acid Research Studies
- Medicinal plant effects and applications
- Botany and Plant Ecology Studies
- Natural product bioactivities and synthesis
- Human Health and Disease
- Drug-Induced Hepatotoxicity and Protection
- Pharmacological Effects of Natural Compounds
- Electromagnetic Fields and Biological Effects
- Genomics, phytochemicals, and oxidative stress
- Neurological Disease Mechanisms and Treatments
- Phytochemistry and Biological Activities
- Bioactive Compounds and Antitumor Agents
- Circadian rhythm and melatonin
- Essential Oils and Antimicrobial Activity
- Urinary Bladder and Prostate Research
- Vitamin C and Antioxidants Research
- Nitric Oxide and Endothelin Effects
- Morinda citrifolia extract uses
- Spaceflight effects on biology
- Medicinal Plants and Neuroprotection
- Phytochemicals and Antioxidant Activities
- Antioxidant Activity and Oxidative Stress
- Fatty Acid Research and Health
- Nigella sativa pharmacological applications
Atatürk University
2015-2025
Cambridge University Press
2010
New York University Press
2010
University of Veterinary Medicine
2010
Erciyes University
2004
Abstract The antioxidant activities (AA), reducing powers (RP) and total phenolic contents (TPC) of methanol water extracts three lichen species, Usnea longissima Ach., florida (L.) Weber ex Wigg. Lobaria pulmonaria Hoffm. were determined in vitro . Of the tested, showed potent activities. extract L. also had highest (87.9 mg/g lyophylisate). For this there was a strong correlation between activity contents. However, similar not observed for U. Although lower content (38.6 lyophylisate), it...
α-Lipoic acid (ALA) has been termed the ‘ideal’ antioxidant, a readily absorbed and bioavailable compound capable of scavenging number free radicals, it used for treating diseases in which oxidative stress plays major role. The present study was designed to gain better understanding positive effects ALA on models acute chronic inflammation rats, also determine its anti-oxidative potency. In an model, three doses (50, 100 200 mg/kg) one dose indomethacin (25 or diclofenac were administered...
One of the common lethal complications septic shock, a major cause morbidity and mortality in patients with severe trauma so on, is acute lung injury. alpha-Lipoic acid (ALA), antioxidant properties, popular agent. Thus, we investigated potential protective effects ALA (200 mg/kg) on sepsis-induced Rats were exposed to cecal ligation puncture (CLP) induce sepsis. Rat groups designed as (a) sham operated, (b) operated + treated, (c) CLP applied, (d) treated. Sixteen hours after induction,...
Inflammation and oxidative stress (OxS) contribute to the pathogenesis of diabetic kidney disease (DKD) contrast-induced nephropathy (CIN). Patients with DKD were found be more prone CIN. Interleukin-33 (IL-33) is a proinflammatory cytokine, but its role in CIN unknown.Thirty male Sprague-Dawley rats enrolled. The first group was comprised healthy (HRs), whereas other four groups made up (DRs), (CIN + DRs), melatonin-treated (MTDRs), DRs (MTCIN DRs). All except HRs received 50 mg/kg/day...
In this study, 1 steroidal and 8 phenolic compounds from Lobaria pulmonaria (L.) Hoffm. Usnea longissima Ach. were isolated their chemical structures characterized by ^1H-NMR, ^{13}C-NMR, DEPT, ^1H-^1H COSY, HMQC, HMBC, IR, UV, MS spectroscopic methods as stictic acid, isidiophorin, rhizonaldehyde, rhizonyl alcohol, pulmonarianin, vesuvianic ergosterol peroxide, usnic diffractaic acid. Among these compounds, L. pulmonaria, was for the first time a natural compound. addition to isolation...
The effect of 900-MHz radiofrequency electromagnetic fields during the adolescence on histological structure rat testis and its androgen estrogen receptors localization
Aims: We examined the protective effect of natural product osajin against sepsis-induced brain damage by targeting 8-hydroxydeoxyguanosine (8-OHdG)/Bcl-2-associated×protein (Bax)/caspase-3 pathway in tissue septic rats. Methods: Osajin was isolated from Maclura pomifera fruit, structure confirmed, and a rat model established cecal ligation puncture (CLP) method. administered to animals with sepsis-associated at 150 300 mg/kg. Following euthanasia, histopathological examination, detection...
Summary Antioxidant vitamins are commonly used as colorant, preventive, sweetener, nutritive and antioxidant materials in food industry. Thus, many studies have been conducted recent years. We performed the present study to understand effects of α‐lipoic acid (ALA), vitamin C E, added into rations Japanese quails, on chronic heat stress. This was carried out five groups as: control, stress, ALA, E groups. Heat stress is applied all except control group. Superficial pectoral muscles tissues...
Gastroprotective effects of α-lipoic acid (ALA) against oxidative gastric damage induced by indomethacin (IND) have been investigated. All doses (50, 75, 100, 150, 200, and 300 mg/kg body weight) ALA reduced the ulcer index with 88.2% to 96.1% inhibition ratio. In biochemical analyses stomach tissues, administration decreased level lipid peroxidation (LPO) activities myeloperoxidase (MPO) catalase (CAT) in which were increased after IND application. also glutathione (GSH) superoxide...
We investigated the effects of antioxidant α-tocopherol on early- and late-phase fracture healing in a rat model. Sixty male Sprague-Dawley rats were randomized into two groups. The right tibia each was fractured manually under anaesthesia, sites fixed with intramedullary Kirschner wires. group received 20 mg/kg intraperitoneally; control intraperitoneal saline injections. Ten from sacrificed day 15, 45 60. In group, malondialdehyde concentrations, measure lipid peroxidation associated...
Abstract Lobaria pulmonaria , a lichen species, has been used in traditional medicine for the treatment of various diseases. This study was designed to determine gastroprotective effect methanol extract L. an indometacin‐induced ulcer model rats. The results showed that gastric lesions were significantly reduced dose‐dependent manner. Furthermore, administration indometacin caused significant decrease levels superoxide, glutathione peroxidase and increase lipid peroxidation level....
Despite efforts to find effective drugs for sepsis-associated acute kidney injury (SA-AKI), mortality rates in patients with SA-AKI have not decreased. Our study evaluated the protective effects of isoflavone osajin (OSJ) on rats by targeting inflammation, oxidative stress, and apoptosis, which represent cornerstones pathophysiological mechanism SA-AKI. Polymicrobial sepsis was induced via cecal ligation puncture (CLP) technique. Markers stress were tissues using biochemical methods. The...