Zong Li

ORCID: 0000-0002-7478-3402
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About
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Research Areas
  • Structural Load-Bearing Analysis
  • Bacteriophages and microbial interactions
  • Geoscience and Mining Technology
  • Geomechanics and Mining Engineering
  • Structural Engineering and Vibration Analysis
  • Structural Analysis and Optimization
  • High voltage insulation and dielectric phenomena
  • Simulation and Modeling Applications
  • Advanced Drug Delivery Systems
  • Industrial Technology and Control Systems
  • Knee injuries and reconstruction techniques
  • Advanced Sensor and Control Systems
  • Advanced Algorithms and Applications
  • Power Transformer Diagnostics and Insulation
  • Vibration and Dynamic Analysis
  • Nanoparticle-Based Drug Delivery
  • RNA Interference and Gene Delivery
  • Advanced Computational Techniques and Applications
  • Hydrological Forecasting Using AI
  • Advanced Decision-Making Techniques
  • Migration, Ethnicity, and Economy
  • Embedded Systems and FPGA Design
  • Catalytic Processes in Materials Science
  • Structural Behavior of Reinforced Concrete
  • Power Systems and Technologies

Zhejiang Sci-Tech University
2025

Tsinghua University
2013-2025

North China University of Science and Technology
2025

Peking University Third Hospital
2019-2024

Shanghai Electric (China)
2024

Nanjing University of Aeronautics and Astronautics
2022-2024

University of Chinese Academy of Sciences
2012-2024

Peking University
2019-2024

North China University of Water Resources and Electric Power
2023-2024

Shaanxi Normal University
2024

Abstract Degradation of extracellular matrix (ECM) underlies loss cartilage tissue in osteoarthritis, a common disease for which no effective disease-modifying therapy currently exists. Here we describe BNTA, small molecule with ECM modulatory properties. BNTA promotes generation components cultured chondrocytes isolated from individuals osteoarthritis. In human osteoarthritic explants, treatment stimulates expression while suppressing inflammatory mediators. Intra-articular injection delays...

10.1038/s41467-019-09839-x article EN cc-by Nature Communications 2019-04-23

Meniscus deficiency, the most common and refractory disease in human knee joints, often progresses to osteoarthritis (OA) due abnormal biomechanical distribution articular cartilage abrasion. However, its anisotropic spatial architecture, complex microenvironment, limited vascularity, meniscus repair remains a challenge for clinicians researchers worldwide. In this study, we developed 3D printing-based biomimetic composite tissue-engineered scaffold consisting of polycaprolactone (PCL)/silk...

10.7150/thno.44270 article EN cc-by Theranostics 2020-01-01

An ultrathin FeS–FeSe<sub>2</sub> lateral heterojunction photocatalyst with nanoscale precision for H<sub>2</sub> evolution.

10.1039/c8ta11456k article EN Journal of Materials Chemistry A 2019-01-01

Multifunctional nanomedicines with active targeting and stimuli-responsive drug release function utilizing pathophysiological features of the disease are regarded as an effective strategy for treatment rheumatoid arthritis (RA). Under inflammatory environment RA, activated macrophages revealed increased expression folate receptor elevated intracellular reactive oxygen species (ROS) level. In this study, we successfully conjugated to polyethylene glycol 100 monostearate film-forming material...

10.3390/pharmaceutics11110582 article EN cc-by Pharmaceutics 2019-11-06

Silk fibroin (SF) is a natural polymer with low immunogenicity and good biocompatibility. However, most silk-based hydrogels formed through chemical or physical cross-linking are brittle, the preparation of which also inevitably introduces cytotoxic agents. Herein, simple strategy presented for synthesizing SF tunable mechanical properties by combining γ-ray radiation ethanol treatment. Neither toxic initiators nor agents utilized during whole procedure. For "soft" hydrogels, compressive...

10.1021/acsabm.9b01062 article EN ACS Applied Bio Materials 2019-12-26
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