A5061563698- Plant-Microbe Interactions and Immunity
- Plant Molecular Biology Research
- Plant Reproductive Biology
- Plant Pathogens and Fungal Diseases
- Biofuel production and bioconversion
- Microbial Natural Products and Biosynthesis
- 14-3-3 protein interactions
- Fungal Biology and Applications
- Bacterial Genetics and Biotechnology
- Plant Gene Expression Analysis
- Microbial Metabolism and Applications
- Enzyme Production and Characterization
- Bacterial biofilms and quorum sensing
- Legume Nitrogen Fixing Symbiosis
- Plant Pathogenic Bacteria Studies
- Microbial Metabolites in Food Biotechnology
- Photosynthetic Processes and Mechanisms
- Enzyme-mediated dye degradation
- Microtubule and mitosis dynamics
- Plant pathogens and resistance mechanisms
- Glioma Diagnosis and Treatment
- Slime Mold and Myxomycetes Research
- Microbial Metabolic Engineering and Bioproduction
- Fungal and yeast genetics research
- Insect and Pesticide Research
Guangxi University
2022-2023
State Key Laboratory For Conservation and Utilization of Subtropical Agro-Bioresources
2023
Nanjing Agricultural University
2018-2022
Chinese Academy of Sciences
2021
Zhejiang Cancer Hospital
2021
University of Chinese Academy of Sciences
2021
Nanjing Forestry University
2018-2019
Purdue University West Lafayette
2000
University Medical Center
1991
University Hospital and Clinics
1991
Understanding the driving forces and intrinsic mechanisms of microbial competition is a fundamental question in ecology. Despite well-established negative correlation between exploitation phylogenetic distance, process interference that exemplified by antagonism remains controversial. Here, we studied genus Bacillus, commonly recognized producer multifarious antibiotics, to explore role patterns biosynthetic gene clusters (BGCs) mediating relationship phylogeny. Comparative genomic analysis...
srfA is an operon required for the production of lipopeptide antibiotic surfactin, competence development, and efficient sporulation in Bacillus subtilis. The expression induced after end exponential growth dependent on products late-growth regulatory genes comP, comA, spo0K. To begin to understand mechanism regulation, promoter region was identified characterized. examine activity, fused lacZ inserted into B. subtilis chromosome as a single copy at SP beta prophage. location transcription...
Members of the Mi14-3-3 gene family interact with target proteins that are widely involved in plant hormone signal transduction and physiology-related metabolism play important roles growth, development stress responses. In this study, 14-3-3s members identified by bioinformatic analysis mango (Mangifera indica L.) genome. The structures, chromosomal distributions, genetic evolution, expression patterns these genes physical chemical properties conserved motifs their analysed systematically....
Background: Melanoma is a highly aggressive, malignant skin tumor with statistically high mortality rate. N6-methyladenosine (m6A) modification involved in variety of biological processes, including tumorigenesis. m6A modifications regulate the fate and functions RNA, such as mRNA stability, nuclear processing, transport, localization, translation, primary microRNA (miRNA) RNA-protein interactions. Several members (including METTL3, METTL14, FTO, ALKBH5, YTHDF2) are actively human cancers....
Mitogen-activated protein kinase (MAPK) signaling pathway plays key roles in sensing extracellular signals and transmitting them from the cell membrane to nucleus response various environmental stimuli. A MAPKKK CgMck1 Colletotrichum gloeosporioides was characterized. Phenotypic analyses of ∆Cgmck1 mutant showed that required for vegetative growth, fruiting body development, sporulation. Additionally, CgMCK1 deletion significant defects wall integrity, responses osmotic stresses. The...
Rhizobacteria devote a relatively large percentage of their genomes to encode bioactive natural products that are important for competition in the rhizosphere. In this study, plant beneficial rhizobacterium Bacillus velezensis SQR9 was discovered produce novel antibacterial fatty acids, Bacillunoic which encoded on genomic island (GI). This GI contains hybrid type I acid synthase (FAS)-polyketide (PKS) system and an ABC transporter. The FAS predicted synthesize primer transferred PKS acids....
ABSTRACT Efficient biofilm formation and root colonization capabilities facilitate the ability of beneficial plant rhizobacteria to promote growth antagonize soilborne pathogens. Biofilm by plant-beneficial Bacillus strains is triggered environmental cues, including oxygen deficiency, but pathways that sense these signals regulate have not been thoroughly elucidated. In this study, we showed ResDE two-component regulatory system in growth-promoting rhizobacterium amyloliquefaciens strain...
Bacterial fruit blotch, caused by seed-borne pathogen Acidovorax citrulli , poses a serious threat to the production of cucurbits globally. Although disease can cause substantial economic losses, limited information is available about molecular mechanisms virulence. This study identified that, random transposon insertion mutant impaired in ability elicit hypersensitive response on tobacco. The disrupted gene this was determined be Aave_0638 which predicted encode YggS family pyridoxal...
S-RNase plays vital roles in the process of self-incompatibility (SI) Rutaceae plants. Data have shown that rejection phenomenon during self-pollination is due to degradation pollen tube RNA by S-RNase. The cytoskeleton microfilaments tubes are destroyed, and other components cannot extend downwards from stigma and, ultimately, reach ovary complete fertilisation. In this study, four gene sequences were identified 'XiangShui' lemon genome ubiquitome. Sequence analysis revealed conserved RNase...
Acidovorax citrulli is a seedborne pathogen that causes bacterial fruit blotch (BFB), global threat to watermelon production. Treating seeds eliminate A. critical component of BFB management, and several strategies have been evaluated mitigate the impact disease. In China, seed producers routinely incubate in juice (fermentation) reduce risk infection by seedling transmission BFB. However, there has limited effort evaluate efficacy fermentation mitigating infection. The current study showed...
Abstract Understanding the driving forces and intrinsic mechanisms of microbial competition is a fundamental question in ecology. Despite well-established negative correlation between exploitation phylogenetic distance, process interference that exemplified by antagonism remains controversial. Here, we studied genus Bacillus , commonly recognized producer multifarious antibiotics, to explore role patterns biosynthetic gene clusters (BGCs) mediating relationship phylogeny. Comparative genomic...
Background: This study aimed to explore the expression of forkhead box Q1 (FOXQ1) and its effects on proliferation apoptosis in human osteosarcoma cell line U2OS. Methods: The FOXQ1 was detected by Western blotting U2OS cells were divided into three groups: experimental group (FOXQ1-siRNA group), negative control (NC-siRNA group) blank (untransfection group). FOXQ1-targeted siRNA transfected FOXQ1-siRNA NC-siRNA group, respectively. mRNA protein levels determined real-time reverse...
目的 探讨星形细胞瘤质子MR波谱(1H-MRS)表现与肿瘤增殖潜力的相关性.方法 术前进行MRI和1H-MRS检查且经手术病理证实的34例星形细胞瘤患者,其中Ⅰ、Ⅱ级(低级别)26例,Ⅲ、Ⅳ级(高级别)8例.34例星形细胞瘤患者中有21例(低级别17例,高级别4例)为均质性肿瘤.增殖细胞核抗原(PCNA)免疫组织化学染色,研究PCNA在高、低级别星形细胞瘤中的表达水平,并与星形细胞瘤1H-MRS的胆碱(Cho)/N-乙酰天冬氨酸(NAA)、Cho/肌酸和磷酸肌酸(Cr)相比较,明确两者间的关系.结果...