A critical challenge arising during a surgical procedure for tumor removal is the determination of margins. Gold nanorods (GNRs) conjugated to epidermal growth factor receptors (EGFR) (GNRs-EGFR) have long been used in detection cancerous cells as expression EGFR dramatically increases once tissue becomes cancerous. Optical techniques identification these GNRs-EGFR are intensively developed based on unique scattering and absorption properties GNRs. In this study, we investigate distribution...

Over the past 2 decades, vertical scar reduction mammaplasty techniques have been gaining more acceptance. However, many surgeons are still hesitant to use it routinely because of uncertainty effectiveness in managing lower pole skin excess. We aimed test its efficacy by using objective anthropometric measurements evaluate long-term breast shape and stability. The study population included 40 129 consecutive women with short-scar followed up for at least 1 year. Breasts were measured...

Abstract Introduction Pediatric burn patients face significant risks of fever and complications, impacting morbidity, mortality, healthcare costs. Despite advancements in care, early identification management these remain challenging. This study aimed to develop validate a Machine Learning (ML) based predictive model using Random Forest (RF) algorithms forecast the likelihood related complications hospitalized pediatric patients. Methods We conducted retrospective analysis admitted tertiary...

Abstract We aimed to characterise the response of locally advanced basal cell carcinoma (BCC) systemic treatment with Vismodegib, a Hedgehog pathway inhibitor, by changes in expression levels genes. Data were collected prospectively on 12 patients treated systemically for BCC. Biopsy samples taken admission and after cessation analysed pathologically NanoString nCounter system quantify 40 signaling Findings compared before treatment, between complete partial responders, localised BCC from 22...

Abstract The coronavirus disease 2019 (COVID-19) pandemic has been challenging global health, in many countries all non-urgent medical treatments were postponed order to focus health systems, workforce and other resources on crucial for COVID-19 patients. pediatric cases are a minority of patients might present atypically. Due an increase burn we decided establish outpatient pre-hospital clinic as intermediate “station”, triage into those who at our hospital, treated via telemedicine. We...

Esthetic concerns and psychosocial distress often accompany auricular deformities malformations in both children their parents. Approximately 30% of newborns are affected by anomalies, with 15% to 20% resulting permanent defects. While surgical intervention is typically considered the gold standard for malformations, a non-surgical approach, such as splinting, molding, or other non-invasive techniques, can effectively address deformations if promptly administered specialist. Microtia,...

Abstract Approximately 30% of newborns have some degree congenital ear anomalies, the minority will resolve spontaneously. Deformations can be treated non-surgically, when diagnosed early, whereas malformations surgically only. The authors use EarWell system proven to achieve excellent results in treating deformations. Although prematurity might raise risk ear-deformations compared term infants, our experience, there is a longer time frame until effective treatment initiated due cartilage...

Minimally-invasive endoscopic strip-craniectomy (or suturectomy) for the repair of craniosynostosis combined with postoperative cranial orthotic molding has been widely adopted in past 2 decades, proving itself as a safe and effective procedure. Over time authors transitioned from performing an strip-craniectomy, to same surgery without endoscope. The here describe our technique compare its results those published literature suturectomies.A retrospective chart review was performed patients...

Diffusion reflectance spectroscopy measurements targeted with gold nanoparticles (GNPs) can identify residual cutaneous squamous cell carcinoma (SCC) in excision borders. Human SCC specimens were stained hematoxylin and eosin to tumor borders, reflected onto an unstained deparaffinized section. reflection of three sites (normal SCC) measured before after GNPs targeting. Hyperspectral imaging showed a mean 2.5 per specimen 1.2 tumor-free (p < 0.05, t-test). detected 25/30 (sensitivity...

Abstract The aim of this report is to describe the combination Crouzon syndrome and acanthosis nigricans with fibrous dysplasia maxilla. diagnosis was confirmed clinically pathologically during Le Fort III osteotomy midface advancement distraction osteogenesis. a known an incidence 1:1,000,000. This first in literature combined dysplasia. As all 3 pathologies are related fibroblasts, they may be different manifestations malfunction single molecular pathway. detection patient important...

Breast reconstruction incidence increased, including preventive surgery. In this context, providing women best surgical care and results is crucial, with minimum complications, such as wound dehiscence skin flap necrosis. Tension-free closure of flaps mandatory for successful healing. However, since not always possible, various techniques have been developed to reduce tension from margins, facilitate primary closure, minimize improve scarring. These investigated in breast surgeries. The aim...

Abstract The Swords of Iron (SOI) War is an armed conflict between Israel and Hamas, which has been taking place in Gaza from October 2023 until the present time writing this article. This war characterized by urban close contact combat. combat equipment, weaponry, protective measures employed, differ markedly those previously documented major conflicts, significantly impacting types injuries sustained soldiers. study examines number injured soldiers combat, field mortality rates, incidence...

Background: The Millard rotation-advancement cleft lip repair is the most commonly performed repair. An extended perialar incision allows for further advancement of lateral element and improved positioning alar base. There a lack data evaluating differences in nasal growth when utilized. This study compares long-term effects on surface area unilateral patients who underwent Methods: Thirty-seven with diagnosis treated primary were studied. A was utilized 16 while 21 standard 3dMD facial...

The temple is an intriguing region of the face with unique anatomic features, such as temporal hairline, concave contour, and close proximity to vital structures like frontal branch facial nerve. However, cancerous skin lesions can plague this sun-exposed and, when excised, it result in large significant defects. Reconstruction area a formidable challenge for surgeons, requires comprehensive knowledge morphology use creative techniques order minimize disruption surrounding functional...

The injection of large volumes silicone oil for lip augmentation can lead to the formation abnormally prominent or projected lips. Conservative treatment measures are largely ineffective. This observational study describes application a surgical technique developed at our center correction oil-induced deformities.Fifty-nine patients presented tertiary medical over 6-year period with complaints deformities caused by injections 2 4 years previously. All had proven refractory conservative...

Department of Plastic and Reconstructive Surgery, Rabin Medical Center, Beilinson Hospital, Petach Tikva, Affiliated With Sackler Faculty Medicine, Tel Aviv University, Aviv, Israel Address correspondence reprint requests to: Asaf Olshinka, MD, Tikva 49100, Israel, or e-mail: [email protected] The authors have indicated no significant interest with commercial supporters.