The fibula free flap became popular in orthopedic oncology for limb-sparing long bone tumor resection. It is particularly suitable intercalary or resection arthrodesis options. In the present series, a surgical reconstruction algorithm was used, enabling each patient to receive personalized technique. During years 1998 2002, 30 patients underwent surgery sarcoma. There were 18 males and 12 females. Their mean age 23 (range, 9 70 years). diagnoses Ewing's sarcoma (11 patients), osteogenic...

The role of tissue expanders in breast reconstruction is well established. Little information exists, however, regarding the incidence and etiology premature removal expander before planned exchange to a permanent implant. purpose this study was review our 10-year experience with identify factors relating expander. This retrospective 770 consecutive patients who underwent over past 10 years. Breast immediate 90 percent patients. Patients were expanded weekly, adjuvant chemotherapy begun...

Over the past 2 decades, vertical scar reduction mammaplasty techniques have been gaining more acceptance. However, many surgeons are still hesitant to use it routinely because of uncertainty effectiveness in managing lower pole skin excess. We aimed test its efficacy by using objective anthropometric measurements evaluate long-term breast shape and stability. The study population included 40 129 consecutive women with short-scar followed up for at least 1 year. Breasts were measured...

Abstract Introduction Pediatric burn patients face significant risks of fever and complications, impacting morbidity, mortality, healthcare costs. Despite advancements in care, early identification management these remain challenging. This study aimed to develop validate a Machine Learning (ML) based predictive model using Random Forest (RF) algorithms forecast the likelihood related complications hospitalized pediatric patients. Methods We conducted retrospective analysis admitted tertiary...

Solid organ recipients are at an increased risk of developing various malignancies. We investigated the incidence, clinical features, and outcome patients diagnosed with head neck cancer after transplantation.A retrospective analysis was undertaken who underwent solid transplantation (kidney, liver, lung, heart) treated our institution from 1992 to 2010.Of 2817 recipients, 175 (6.1%) developed 391 Cutaneous malignancies were most common (93%): squamous cell carcinoma (SCC; 51%) basal (BCC;...

Immunosuppression is strongly associated with an increased risk of developing cutaneous squamous cell carcinoma (cSCC). Studies on solid organ transplant recipients (SOTR) and chronic lymphocytic leukemia (CLL) patients have already demonstrated higher rates aggressive cSCC tumors in these populations compared to immunocompetent controls. other immunosuppressed patient groups are scarce. This study was aimed at assessing the effects different immunomodulating conditions diagnosed cSCC. We...

Abstract Background A myriad of technologies are available for the treatment aging skin. These, however, still lack ability to combine immediate, short‐term and long‐term aesthetic results with no downtime. Furthermore, fine wrinkles on large surfaces remains challenging, as does delicate regions, such dorsal hand, neck, chest. Objectives The aims this study were evaluate well efficacy safety a new skin remodeling device that pneumatically accelerates jet hyaluronic acid (HA) solution under...

Background: Improvements in burn care during the last two decades call for new prediction models of morbidity and mortality. The aim study was to identify parameters that are predictive major factors risk mortality patients with injury. Methods: charts 249 (236 survivors) aged 1 94 years who were treated second- third-degree burns from 1995 2002 reviewed. A multivariate linear stepwise regression model fitted data predict length hospitalization, operations, rate. Results: Survivors' mean...

Breast reconstruction and augmentation have become a standard surgical treatment worldwide as advancements in medicine technology enable safer simpler procedures. A variety of implants is used to mimic natural breast both appearance texture. The most common complication such procedures capsular contracture encircling the implant, occurring approximately 10%. As date, mainly estimated by physical examination breast, which standardized according Baker score.In cross-sectional study, we...

Increasing evidence suggests that adipose tissue contains mesenchymal stem cells (MSC) possess the ability to transdifferentiate into other cell types including hepatocytes, similar bone marrow-derived cells. The existence of precommitted in MSC population may explain transdifferentiation.Our aim was identify a putative hepatocyte-like precursor human tissue.We analysed 'basal' hepatic potential undifferentiated, naïve adipose-derived (hADMSC). hADMSC were isolated from and characterized for...

Abstract Background Antecedent trauma has been implicated in the causation of soft tissue tumors. Several criteria have established to define a cause-and-effect relationship. We postulate possible mechanisms genesis tumors following antecedent traumatic injury. Case presentation present 27-year-old woman with paraspinal desmoid tumor, diagnosed 3-years motor vehicle accident. Literature is reviewed. Conclusion Soft arising at site previous may be desmoids, pseudolipomas or rarely, other...

Amelanotic melanomas (AMMs) account for a small proportion of all melanomas. They pose risk delayed diagnosis and, consequently, poor prognosis. AMMs may atypically present as pyogenic granuloma-like lesion. This study sought to investigate the prevalence and clinical histological features AMM masquerading granuloma. The database tertiary medical center was screened patients pathologically diagnosed with melanoma in 2005-2016. Those suspected primary (i.e. pre-excision) granuloma were...

BACKGROUND Angiokeratomas of Fordyce are typically asymptomatic vascular lesions characterized by blue-to-red papules with a scale surface, most often located on the scrotum. Although considered benign, may bleed, either spontaneously or secondary to rupture, leading patient anxiety and social embarrassment. OBJECTIVE The objective was determine safety effectiveness 585-nm pulsed dye laser for treatment angiokeratomas Fordyce. METHODS Twelve patients Fitzpatrick skin type II IV were treated...

Autologous muscle flaps are commonly used to reconstruct defects that involve impairment. To maintain viability and functionality of these flaps, they must be properly vascularized innervated. Tissue-engineered muscles could potentially replace autologous tissue, but still require establishment sufficient innervation ensure functionality. In this study, we explored the possibility innervating engineered grafts transplanted an abdominal wall defect in mice, by transferring native femoral...

Demand for nonsurgical esthetic body procedures has led to the development of noninvasive techniques reducing localized subcutaneous adipose tissue.This study assessed multiple treatments with nonthermal focused ultrasound abdominal treatment excess fat deposits.Subjects were randomly assigned Group 1 a 4-week control phase before undergoing 3 reduction treatments, at 2-week intervals, or 2 immediate treatment. Weight, circumference, tolerability treatment, subject satisfaction, and adverse...

The integrity of each the components auricle is important for its overall aesthetic appearance. Cartilage-exposing nonhelical defects that are too large to be closed primarily without distorting may reconstructed with local flaps.The objective was present our experience reconstruction medium-sized using a variety simple, one-stage flaps.Eighteen patients who underwent auricular flaps at center from 2003 2006. Defect size ranged about 10 20 mm. Various methods were used as follows: conchal...

Abstract We aimed to characterise the response of locally advanced basal cell carcinoma (BCC) systemic treatment with Vismodegib, a Hedgehog pathway inhibitor, by changes in expression levels genes. Data were collected prospectively on 12 patients treated systemically for BCC. Biopsy samples taken admission and after cessation analysed pathologically NanoString nCounter system quantify 40 signaling Findings compared before treatment, between complete partial responders, localised BCC from 22...

Background: Suicide bomb injuries vary in form and magnitude. From the onset of second Palestinian "intifada" October 2000 until January 2004, 577 victims suicide bombings were admitted to Hadassah-Hebrew University Medical Center. A single bomber carrying a handbag or belt containing multiple metal objects explosives carried out most attacks. As result, many suffered massive tissue destruction addition conventional blast injuries. Methods: This article describes management this...

A series of 20 patients (15 men and 5 women) suffering from malignant melanoma the scalp is reported. Their epidemiologic data outcome are described. The ages ranged 48 to 78 years (mean 63 years). Analysis cases demonstrated that lesions occurring posterior tragal line (in hair-bearing area) have worst prognosis. 5-year survival rate was poor; 12 died within this period. Two representative described, preventable aspects disease emphasized.