A5079637173- Hormonal and reproductive studies
- Hypothalamic control of reproductive hormones
- Neuroendocrine regulation and behavior
- Stress Responses and Cortisol
- Neuroscience and Neuropharmacology Research
- Neuroinflammation and Neurodegeneration Mechanisms
- Estrogen and related hormone effects
- Circadian rhythm and melatonin
- Neurogenesis and neuroplasticity mechanisms
- Memory and Neural Mechanisms
- Biochemical effects in animals
- Sexual function and dysfunction studies
- Neurological Disease Mechanisms and Treatments
- Anesthesia and Neurotoxicity Research
- Menopause: Health Impacts and Treatments
- Sleep and Wakefulness Research
- Sexual Differentiation and Disorders
- Neurobiology and Insect Physiology Research
- Sperm and Testicular Function
- Ovarian function and disorders
- Parasitic infections in humans and animals
- Insect and Pesticide Research
- Steroid Chemistry and Biochemistry
- Acute Ischemic Stroke Management
- Cell death mechanisms and regulation
Mexican Social Security Institute
1982-2019
Hospital de Especialidades
2006-2013
Centro Medico Nacional Siglo XXI
1997-2012
Universidad Autónoma Metropolitana
1976-2003
Universidad Nacional Autónoma de México
1971-1994
National Institute of Nutrition
1994
Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán
1990
Autonomous University of Tlaxcala
1982-1986
University of Gothenburg
1976
Abstract: Consensus on neuroprotection has pointed out the relevance of long‐term morphological and functional evaluation effectiveness putative neuroprotective procedures. In present study, place learning (Morris water maze) working memory (eight‐arm Olton radial were evaluated in adult male rats 90 days after 15 min global cerebral ischemia (four‐vessel occlusion) followed by continuous i.v. infusion (10 mg/kg/hr) melatonin (Isch + Mel) or vehicle Veh) for 6 hr, pyramidal neuron population...
The effect of 5-α-dihydrotestosterone (DHT) on ovarian compensatory hypertrophy (OCH) and estrous behavior were studied in Wistar rats. Unilateral ovariectomy 5 day cycling rats resulted significant the remaining ovary IS days after operation. Administration 50, 200 or 1000 μg DHT propionate daily for 15 blocked OCH. degree blockade was dose dependent. Bilateral implantation free medial hypothalamus inhibited OCH, while unilateral either pituitary failed to prevent Treatment ovariectomized...
Purpose: To assess the long-term neuroprotective effects of progesterone (P $_{4}$ ) and allopregnanolone (ALLO) on functional morphological parameters integrity hippocampus, after global cerebral ischemia. Methods: Adult male Sprague-Dawley rats were subjected to a transient severe (20 min) forebrain ischemia (Isch) episode treated with P $_4$ or ALLO (8 mg/kg i.v.) its vehicle, at 20 min, 2, 6, 24, 48 72 h Rats Sham procedures, intact included as non-ischemic controls. Three months...
Purpose: To analyze the cytoarchitectural characteristics of remaining pyramidal neurons in hippocampal CA1 subfield rats, four months after global cerebral ischemia (GCI) and progesterone treatment. Methods: Dendritic arborization, density shape dendritic spines brains intact or rats submitted 120 days earlier to GCI treatment with (8 mg/kg) its vehicle, at 15 min, 2, 6, 24, 48, 72 h onset reperfusion, were analyzed samples processed by a modified Golgi method. Results: Few impregnated...
The synthetic steroid 7α-methyl-19-nortestosterone (MENT) binds with high affinity to the androgen receptor and exerts biological effects at some peripheral target tissues a potency greater than that of naturally occurring androgens. In vivo, MENT does not undergo enzymatic 5α-reduction as consequence, its biologic action on prostate other organs male reproductive tract is amplified testosterone (T). Thus, in castrated rats, dose will maintain normal muscle mass gonadotropin levels seminal...