A5101408407- Bone Tissue Engineering Materials
- biodegradable polymer synthesis and properties
- Dental Implant Techniques and Outcomes
- Graphene and Nanomaterials Applications
- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Thyroid Disorders and Treatments
- Synthesis and properties of polymers
- Silicone and Siloxane Chemistry
- Electrochemical sensors and biosensors
- Antimicrobial agents and applications
- Conducting polymers and applications
- Composting and Vermicomposting Techniques
- Orthopaedic implants and arthroplasty
- Thyroid Cancer Diagnosis and Treatment
- Advanced biosensing and bioanalysis techniques
- Animal Virus Infections Studies
- Molecular Sensors and Ion Detection
- Head and Neck Anomalies
- Ginkgo biloba and Cashew Applications
- Fiber-reinforced polymer composites
- Hepatitis B Virus Studies
- Carbon Nanotubes in Composites
- Facial Trauma and Fracture Management
- Waste Management and Recycling
Yan'an University
2018-2024
Qinghai University
2023-2024
Qinghai Provincial Peoples Hospital
2023-2024
Southwest University
2023
Huazhong Agricultural University
2023
Beihai People's Hospital
2023
Chongqing Medical University
2022
The Affiliated Yongchuan Hospital of Chongqing Medical University
2022
Ministry of Education of the People's Republic of China
2019
Northwest University
2019
Among various biomaterials employed for bone repair, composites with good biocompatibility and osteogenic ability had received increasing attention from biomedical applications. In this study, we doped selenium (Se) into hydroxyapatite (Se-HA) by the precipitation method, prepared different amounts of Se-HA-loaded poly (amino acid)/Se-HA (PAA/Se-HA) (0, 10 wt%, 20 30 wt%)
To investigate the adult iodine nutrition and prevalence of thyroid diseases in Qinghai Province, analyze correlation between diseases, so as to provide a basis for adjusting salt iodization plan Province.Using cluster stratified sampling method select 2628 permanent residents over 18 years old Province questionnaire survey, physical examination, color ultrasound, laboratory index detection.1. The coverage iodized adults is 99.71%. 2. detection rates disorders were follows: Clinical...
To investigate the epidemiological characteristics of hypothyroidism in Qinghai Province, analyze its related influencing factors, establish normal reference range thyroid function, and explore relationship between hormone (THs), stimulating (TSH) metabolic syndrome (MS) population within range, so as to provide some scientific basis for prevention treatment Province.
Abstract Bacterial cellulose (BC) and goat bone apatite (GBA) composites were fabricated by a dissolving method. The 4‐methylmorpholine‐4‐oxide (NMMO) served as the solvent for BC. Goat was added to NMMO solution of BC, so shape material could be easily controlled using appropriate molds. expected from immersion in water‐bath formed lyophilization. results indicated that GBA homogenously distributed into BC matrix some interaction at interface between GBA. crystallinity decreased with...
A ternary composite of poly(amino acid), hydroxyapatite, and calcium sulfate (PAA/HA/CS) was prepared using in situ melting polycondensation method evaluated terms mechanical strengths, vitro degradability, bioactivity, as well vivo biocompatibility. The results showed that the exhibited a compressive strength 147 MPa, bending 121 tensile 122 modulus 4.6 GPa. After immersion simulated body fluid, decreased from to 98 MPa for six weeks 75 eight weeks, both them kept stable following soaking...
‘Aniono’ double helicates and grids were constructed using PO<sub>4</sub><sup>3−</sup> anions a bis–tris(urea) ligand interconverted by changing the counter-cation.
Chiral nanoparticles (C-NPs) play a crucial role in biomedical applications, especially their biological effects on cytotoxicity and metabolism. However, there are rare reports about the antivirus property of C-NPs working mechanism. Here, three different types chiral ZnO NPs (l-ZnO, d-ZnO, dl-ZnO) were prepared as enantioselective antivirals. Biocompatibility test results showed that varied significantly cytotoxicity. Evaluation against porcine reproductive respiratory syndrome virus...
A kind of novel poly(phenylene sulfide)s ( PPSs ) containing a chromophore group were synthesized by the reaction dihalogenated monomer and sodium sulfide Na 2 S . x H O) via nucleophilic substitution polymerization under high pressure. The polymers characterized Fourier transform infrared spectroscopy, ultraviolet fluorescence XRD, DSC, TGA, mechanical testing dissolvability experiments. intrinsic viscosity obtained with optimum synthesis conditions was 0.22 − 0.38 dl g −1 (measured in...
Ternary biocomposites of dicalcium phosphate (DCP), calcium sulfate (CS), and poly(amino acid) copolymer (PAA) could be used as a promising degradable biomimic bone substitute. Using an in vitro degradation model, we evaluated the influence polymerization conditions, initial amino acids, (DCP + CS)/PAA ratio on resulting materials. PAA was affected by both conditions DCP/CS/PAA composites ratio. certain acids (75% ε‐aminohexanoic acid, 19% γ‐aminobutanoic 4% l ‐proline, 2% ‐lysine) (i.e.,...
Poly(amino acid) (PAA)‐based nanocomposites were synthesized by in situ melting polycondensation with various carbon nanotube (CNT) loadings; the morphology, thermal, mechanical, electrical, and biocompatible properties of resulting investigated characterized. The nanotubes dispersed within polymer matrix without need for coupling agents or surfactants. crystallization temperature showed a gradual rise increasing CNT loading, confirming that act as nucleating PAA crystallization. increased...
The aim of this study was to evaluate the thermal properties and in vivo interface performance poly(amino acid) (PAA) a composite containing PAA, hydroxyapatite (HA), calcium sulfate (CS), with respect their suitability for skull repair. Biocompatibility evaluated by implantation materials into muscles rabbits eight weeks. Skull repair assessed implanting compact PAA/HA/CS (c-PAA/HA/CS), one-side-porous (p-PAA/HA/CS) rabbit calvarial defects. results showed that possessed good heat...
ABSTRACT In this study, we focused on the surface modification of a novel poly(amino acid) (PAA)/hydroxyapatite/calcium sulfate composite and effect its cellular responses. The was performed by sandblasting (sample S2), calcium chloride ethanol saturated solution etching S3), formic acid S4) followed in vitro culturing osteoblast‐like cells. obtained results indicate that new interface formed during modification, modified changed with respect to morphology physical abrasion. etchant etched...
Abstract Bacterial infection caused by medical material is a common problem in the field of medicine. In this work, we aim to develop novel antimicrobial bioplastic with potential value. A composite composed polyamino acid (PAA) and titanium dioxide/silver nanoparticles (TiO 2 /Ag NPs) was synthesized situ melting polycondensation different TiO loadings. The morphological, antibacterial, mechanical, thermal, cytotoxicity properties PAA/TiO composites were investigated. results showed that...
A thiourea-detecting fluorescence sensor with Hg2+ as a switch was developed using nitrogen-doped graphene quantum dots (N-GQDs). The surface of N-GQDs had many organic functional groups on which effectively bound and turned off the N-GQDs. by thiol group thiourea that strongly formed Hg2+/thiourea complexes. After constructing sensor, experimental conditions parameters, such pH concentration, were investigated optimized. Under optimum conditions, constructed showed high sensitivity to at...
A poly(amino acid)/β‐Ca 2 SiO 4 (PAA/β‐Ca ) bioactive composite was prepared by in situ melting polymerization. The composition, structure, and morphology were characterized infrared spectrometry, X‐ray diffraction, photoelectron spectroscopy, scanning electron microscopy, differential calorimeter. results indicated that the β‐Ca particles uniformly distributed PAA matrix some interaction found at interface between . crystallinity of decreasing with increase content. bioactivity evaluated...
A composite of hydroxyapatite (HA) and polymers prepared from amino acids glycolic acid (PAG) was synthesized using an in situ melting polycondensation method. The vitro degradability bioactivity the were evaluated, as well its vivo biocompatibility based on subcutaneous osseous implantation samples New Zealand white rabbits for 8 weeks. results showed that PAG/HA had higher than PAG a typical apatite morphology after immersion simulated body fluid 5 days. Both alone excellent...
Abstract Traditional Chinese medicines (TCMs)/nanopreparations as viral antagonists exhibited a structure–function correlation, i.e., the differences in surface area/volume ratio caused by variations shape and size could result different biochemical properties biological activities, suggesting an important impact of morphology structure on antiviral activity TCM-based nanoparticles. However, few studies paid attention to this aspect. Here, effect nanoparticles with morphologies their was...