A5053249473- Animal Disease Management and Epidemiology
- Animal Virus Infections Studies
- Effects of Environmental Stressors on Livestock
- Viral gastroenteritis research and epidemiology
- Reproductive Physiology in Livestock
- Virus-based gene therapy research
- Viral Infections and Immunology Research
- Immune Response and Inflammation
- Microbial infections and disease research
- Animal Behavior and Welfare Studies
- Milk Quality and Mastitis in Dairy Cows
- Immune Cell Function and Interaction
- Genetic and phenotypic traits in livestock
- Mycobacterium research and diagnosis
- Animal Nutrition and Physiology
- Vector-Borne Animal Diseases
- Animal health and immunology
- Cytokine Signaling Pathways and Interactions
- Tuberculosis Research and Epidemiology
- T-cell and Retrovirus Studies
- Viral Infectious Diseases and Gene Expression in Insects
- Influenza Virus Research Studies
- IL-33, ST2, and ILC Pathways
- SARS-CoV-2 and COVID-19 Research
- Ruminant Nutrition and Digestive Physiology
University of Brescia
1993-2022
Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna "Bruno Ubertini"
2012-2021
University of Aosta Valley
2013
Istituto Zooprofilattico Sperimentale del Piemonte Liguria e Valle d'Aosta
2013
Istituto Nazionale di Ricerca per gli Alimenti e la Nutrizione
2010
Istituto Zooprofilattico Sperimentale delle Venezie
1997-2005
Istituti Ospitalieri di Cremona
1997
Dry and early lactation periods represent the most critical phases for udder health in cattle, especially highly productive breeds, such as Holstein Friesian (HF). On other hand, some autochthonous cattle Rendena (REN), have a lower prevalence of mastitis transition-related diseases. In this study, milk microbiota 6 HF 3 REN cows, all raised on same farm under conditions, was compared. A special focus placed transition period to define bacterial groups’ with plausible effect mammary gland...
Subclinical ketosis (SCK) may impair white blood cell (WBC) function and thus contribute to the risk of disease postpartum. This preliminary study investigated changes occurring in immune system before onset elucidate their role occurrence SCK. A group 13 Holstein dairy cows were housed tie-stalls retrospectively divided into 2 groups based on levels β-hydroxybutyrate (BHB) measured plasma between calving day 35 d from (DFC). Levels BHB <1.4 mmol/L found 7 (control cows, CTR group) >1.4 6 at...
African swine fever (ASF) is a devastating disease for which there no vaccine. The ASF virus (ASFV) can infect dendritic cell (DC), but despite the critical role these cells play in induction of adaptive immunity, few studies investigated their response to ASFV infection. We characterized vitro interactions porcine monocyte-derived DCs (moDC) with virulent (22653/14), low (NH/P68) and an avirulent (BA71V) strain. At high multiplicity infection (MOI = 1), all three strains infected immature...
Immunostimulants represent a modern and promising tool in aquaculture, enhancing the resistance of cultured fish to disease stress. This study investigated effect combination dietary glucans, alpha-tocopherol ascorbic acid on innate immune response sea bass (Dicentrarchus labrax). After 5 weeks adaptation commercial diet containing 100 p.p.m. 200 alpha-tocopherol, were switched supplemented with 2% beta-1.3/beta-1.6 glucans at 500 The was given body weight per day over 2-week period, every 3...
Many apparently healthy cows show marked inflammatory conditions around calving, associated with endocrine and metabolic changes. To prevent the above conditions, a low-dose, oral interferon-alpha (IFN-alpha) treatment was carried out on periparturient, multiparous dairy cows. In first trial, 10 received IU of IFN-alpha/kg BW daily during last 2 wk pregnancy. second 4 0.5 until d 5 lactation. both trials, homogenous group untreated used as control. All were monitored, month before after for...
African Swine Fever Virus (ASFV) has tropism for macrophages, which seems to play a crucial role in disease pathogenesis and viral dissemination. Previous studies showed that ASFV developed mechanisms evade type I interferon (IFN) responses. Hence, we analyzed the ability of strains diverse virulence modulate IFN-β IFN-α Porcine monocyte-derived macrophages un-activated (moMΦ) or activated with (moMΦ + FN-α) were infected virulent (22653/14) attenuated (NH/P68) strains, expressions 17...
AbstractIn pigs, the genetic selection for lean, large muscle blocks and fast growth has been linked to an increased prevalence of metabolic diseases such as porcine stress syndrome mulberry heart disease. These are associated with cardiovascular inadequacy, which may lead oxidative stress. In present study, reactive oxygen metabolites (ROMs) anti-oxidant power (OXY) in sera different swine groups were investigated. The following selected (each around 80 kg body weight): wild boars (WB),...
The aim of this study was to investigate the effects long-distance road transport (19 h, from Poland Italy) during 2 seasons (summer vs. winter) on clinical and hematological variables in calves. environmental temperature range that could compromise thermoregulation system (thermal stress) calves tested. For 7 Holstein each transport, BW rectal (RT) were measured, blood samples collected at farm origin, before loading transit center (T2), after unloading destination (T3), 1, 2, 3, 4 d...
The study was based on data collected during 5 yr (2003-2007) and aimed at assessing the effects of month, slaughter house destination (differing for stocking density, openings, brightness, cooling device types), length journey, temperature-humidity index (THI) mortality heavy pigs (approximately 160 kg live weight) transport lairage. Data were obtained from 24,098 journeys 3,676,153 transported 1,618 farms to 3 houses. Individual shipments unit observation. terms dead arrival (DOA) in pen...
Clinical immunological and haematological parameters, along with clinical conditions growth rate, were studied in 413 male Holstein Frisian calves introduced into a large centre for genetic selection different seasons of the year. Abnormalities revealed by laboratory tests great majority after transportation stress, general tendency to restoration physiological values being evident thereafter. Laboratory parameters highly correlated disease conditions: three exceptions only, animals showed...
Interferon-alpha (IFN-α) shows potent immunomodulatory properties, which underlies its use for low-dose oral treatments of diverse viral infections and immunopathological conditions. The studies on administration have been hampered by the lack recognized in vitro models, reproducing vivo control action IFN-α over inflammatory cytokine responses. Owing to these reasons, aim our study was validate IPEC-J2 (a continuous cell line porcine intestinal epithelial cells) as a reporter system...
ABSTRACT Avian influenza A viruses have gained increasing attention due to their ability cross the species barrier and cause severe disease in humans other mammal as pigs. H3 particularly H3N8 viruses, are highly adaptive since they found multiple avian hosts. not been isolated yet from humans; however, a recent report showed that equine (IAVs) can be pigs, although an established infection has observed thus far this host. To gain insight into possibility of IAVs vitro experiments...