A5090666733- DNA Repair Mechanisms
- Lung Cancer Research Studies
- Genetic factors in colorectal cancer
- Cancer Genomics and Diagnostics
- Cancer therapeutics and mechanisms
- Cancer Mechanisms and Therapy
- Cancer, Lipids, and Metabolism
- Pituitary Gland Disorders and Treatments
First Hospital of Jiaxing
2022
Jiaxing University
2022
Excision repair cross-complementation group 6 like (ERCC6L), a polo-like kinase 1 (PLK1)-interacting checkpoint helicase, confers high risk of cancer and enhances the progression variety cancers. The present investigation aimed to elucidate pan-cancer expression patterns ERCC6L examine possibility using this gene for patient diagnosis prognosis.The in normal patients at various clinical stages were explored based on TCGA datasets. Subsequently, Bioinformatics techniques then used analyze...
Previous studies have suggested that pituitary tumor transforming gene family serves as an oncogene in human cancers. However, the underlying molecular mechanisms of (PTTG) gastric cancer are unclear. This study aimed to explore expression patterns, biological functions, and potential regulatory mechanism PTTG cells. Results showed genes were highly expressed tissues correlated with low survival outcomes. Further, it was noted regulation PTTG3P associated miR-129-5p miR-383-5p. A...
Background: Mitochondria are at the heart of a number metabolic pathways providing enormous energy for normal cell growth and regulating tumor as well survival. Mitochondrial topoisomerase I (TOP1MT) is type IB found in mitochondria vertebrates. However, no pan-cancer analysis TOP1MT has been reported. This study aims to explore expression tissues identify whether it can be target mitochondrial anticancer therapy. Methods results: The original data 33 different types cancer patients were...