A5024859627- Epilepsy research and treatment
- Pharmacological Effects and Toxicity Studies
- Pharmaceutical studies and practices
- Nutrition and Health Studies
- Pregnancy and Medication Impact
- Psychosomatic Disorders and Their Treatments
- Neurological disorders and treatments
- EEG and Brain-Computer Interfaces
- Neuroscience and Neuropharmacology Research
- Diet and metabolism studies
- Pharmaceutical Economics and Policy
- Bipolar Disorder and Treatment
- Drug Transport and Resistance Mechanisms
- Neurological and metabolic disorders
- Maternal Mental Health During Pregnancy and Postpartum
- Neural dynamics and brain function
- Breastfeeding Practices and Influences
- HIV/AIDS Research and Interventions
- Functional Brain Connectivity Studies
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Cardiovascular Syncope and Autonomic Disorders
- Metabolism and Genetic Disorders
- RNA modifications and cancer
- Neurogenetic and Muscular Disorders Research
- Amino Acid Enzymes and Metabolism
Postgraduate School of Molecular Medicine
2012-2025
Neuro Device (Poland)
2025
Centrum Medyczne Kształcenia Podyplomowego
2005-2017
Medical University of Warsaw
2017
Institute for Postgraduate Medical Education
1999
<h3>Objective:</h3> To assess the risk of major congenital malformations (MCMs) in association with maternal use valproic acid (VPA) monotherapy or adjunctive therapy, and its relationship dose. <h3>Methods:</h3> The analysis was based on prospectively acquired data from EURAP, a registry enrolling women treated antiepileptic drugs (AEDs) early pregnancy, which primary outcome is presence MCMs at 1 year after birth. Exposure defined as type dose AEDs time conception. A comparison made among...
Abstract The contemporary use of interictal scalp electroencephalography (EEG) in the context focal epilepsy workup relies on visual identification epileptiform discharges. high-specificity performance this marker comes, however, at a cost only moderate sensitivity. Zero-crossing interval analysis is an alternative to Fourier for assessment rhythmic component EEG signals. We applied method standard recordings 78 patients divided into 4 subgroups: temporal lobe (TLE), frontal (FLE),...
Clinical diagnosis of epilepsy depends heavily on the detection interictal epileptiform discharges (IEDs) from scalp electroencephalographic (EEG) signals, which by purely visual means is far straightforward. Here, we introduce a simple signal analysis procedure based EEG zero-crossing patterns can extract spatiotemporal structure voltage fluctuations. We analyzed simultaneous and intracranial recordings patients with pharmacoresistant temporal lobe epilepsy. Our data show that large...
The objective of this multinational open‐label, prospective study was to collect, under naturalistic conditions, data on the effectiveness and tolerability first‐line monotherapy with valproate in subjects newly or recently diagnosed focal onset epilepsy. Patients were treated sustained release sodium valproate. Seizure control occurrence adverse events assessed after 6 months. Around 1192 adults 792 children included. mean daily dose 683 mg 987 adults. retention rate at months 90.0%. At...
Data from literature suggest that the rate of caesarean section (CS) in women with epilepsy (WWE) is higher than general population. In Poland, there neither a national registry nor another data set to access outcome pregnancy WWE. Therefore, we address this gap by prospectively studying CS rates among 1021 WWE pregnancies at single centre, their trends over time, and factors increasing likelihood CS. To determine whether diagnosis itself increased likelihood, mixed models were used analyse...
The resection of an epileptic focus provides a chance for seizure outcome regression, which markedly influences the level patients' quality life. One its dimensions is satisfaction with one's sexual Patients epilepsy usually report low due to commonly diagnosed disturbances functions characterized by multifactorial etiology. aim study was assess their life in patients after surgical focus. group included 63 who had undergone neurosurgical ward. conducted present authors' own tool consisting...
The effectiveness of the treatment depends on adequate dosage medications. In clinical practice, drugs are often used at doses that too low, which results in suboptimal levels improvement. aim study was to evaluate effects increasing dose previously taken pregabalin a group patients with focal epilepsy and generalized anxiety disorder (GAD).This open involved 993 (46 ± 14 years old) suffering from seizures concomitant GAD treated add-on therapy. severity assessed GAD-7 Scale. number...