A5040760348- Spectroscopy Techniques in Biomedical and Chemical Research
- Gold and Silver Nanoparticles Synthesis and Applications
- Biosensors and Analytical Detection
- Spectroscopy and Chemometric Analyses
- Advanced biosensing and bioanalysis techniques
- Quantum Dots Synthesis And Properties
- Plasmonic and Surface Plasmon Research
- Heavy Metals in Plants
- Nonlinear Optical Materials Studies
- Banana Cultivation and Research
- Hormonal and reproductive studies
- Electrochemical Analysis and Applications
- Nanoparticles: synthesis and applications
- Melamine detection and toxicity
- Electrochemical sensors and biosensors
- Agricultural and Food Sciences
- Protein Interaction Studies and Fluorescence Analysis
CIC biomaGUNE
2022
Centro de Investigación Biomédica en Red
2022
Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine
2022
The Ohio State University
2020-2021
University of Victoria
2017-2021
Universidade Estadual de Campinas (UNICAMP)
2015-2017
Single molecule surface-enhanced Raman spectroscopy (SM-SERS) has the potential to revolutionize quantitative analysis at ultralow concentrations (less than 1 nM). However, there are no established protocols generalize application of this technique in analytical chemistry. Here, a protocol for quantification using SM-SERS is proposed. The approach aims take advantage stochastic nature single-molecule regime achieved lower limits (LOQ). Two emerging contaminants commonly found aquatic...
The ability to locate and identify molecular interactions in cells has significant importance for understanding protein function biology. Functionalized metallic nanoparticles have been used as probes tracking drug delivery because of their carry therapeutic agents readily functionalized surfaces. In this work, we present a super-resolution surface-enhanced Raman scattering (SERS) approach imaging membrane receptors interacting with peptide-functionalized gold nanostars (AuNS). αvβ3 integrin...
Signal intensity fluctuations are a ubiquitous characteristic of single-molecule surface-enhanced Raman scattering (SERS). In this work, we observed SERS (SIFs) from single nanoparticles fully coated with an adsorbate layer. Fluctuations dry, assigned to dynamic molecule/metal environment wherein atomic-scale reconstructions support SERS. Using super resolution imaging techniques, were able pinpoint the positions subparticle precision. We that fluctuation events separated spatially,...
Surface-enhanced Raman scattering (SERS)-encoded nanoparticles are used for bioimaging, on account of their well-defined spectra and biocompatibility, which allow long incubation times with high signal stability no cytotoxicity. However, reliable analysis SERS bioimaging requires quantification the amount encoded that have been taken up by cells effect subsequent dilution due to cellular division (mitosis). Although methods such as elemental flow cytometry can be quantify nanoparticle...
Challenges investigating molecules on plasmonic nanostructures have limited understanding of these interactions. However, the chemically specific information in surface-enhanced Raman scattering (SERS) spectrum can identify perturbations adsorbed to provide insight relevant applications sensing, catalysis, and energy conversion. Here, we demonstrate spectrally resolved SERS imaging, simultaneously image collect spectra from individual nanoparticles. We observe intensity frequency...