A5101999063- Cardiovascular and Diving-Related Complications
- High Altitude and Hypoxia
- Circular RNAs in diseases
- Human Pose and Action Recognition
- MicroRNA in disease regulation
- Advanced Welding Techniques Analysis
- Extracellular vesicles in disease
- Colorectal Cancer Surgical Treatments
- Human Motion and Animation
- Cancer, Hypoxia, and Metabolism
- RNA modifications and cancer
- Gastric Cancer Management and Outcomes
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Ombudsman and Human Rights
- Welding Techniques and Residual Stresses
- Bone Metabolism and Diseases
- Global Political and Economic Relations
- Image and Object Detection Techniques
- Cancer-related molecular mechanisms research
- Microstructure and mechanical properties
- Nerve injury and regeneration
- Gun Ownership and Violence Research
- Policing Practices and Perceptions
- Enhanced Recovery After Surgery
- Ferroptosis and cancer prognosis
Zhengzhou University
2023-2025
Zhengzhou Children's Hospital
2023-2025
KTH Royal Institute of Technology
2021-2024
Chengdu University
2015-2024
Second Military Medical University
2018-2023
Chinese Academy of Sciences
2022
Shanghai Institute of Materia Medica
2022
Peking University People's Hospital
2022
Peking University
2022
Qilu Hospital of Shandong University
2017-2020
Abstract Background As important players in cell-to-cell communication, exosomes (exo) are believed to play a similar role promoting fracture healing. This study investigated whether derived from bone marrow mesenchymal stem cells (BMMSC-Exos) could improve healing of nonunion. Methods BMMSC-Exos were isolated and transplanted into the site rat model femoral nonunion (Exo group) every week. Moreover, equal volumes phosphate-buffered saline (PBS) exosome-depleted conditioned medium (CM-Exo)...
Severe spinal cord injury (SCI) is caused by external mechanical injury, resulting in unrecoverable neurological injury. Recent studies have shown that exosomes derived from bone marrow mesenchymal stem cells (BMSCs-Exos) might be valuable paracrine molecules the treatment of SCI. In this study, we designed SCI models vivo and vitro then investigated possible mechanism successful repair BMSCs-Exos. vivo, established one Sham group two model groups. The Basso, Beattie, Bresnahan (BBB) scores...
The evolution of autonomous driving has made remark-able advancements in recent years, evolving into a tangible reality. However, human-centric large-scale adoption hinges on meeting variety multifaceted requirements. To ensure that the system meets user's intent, it is essential to accurately discern and interpret user commands, especially complex or emergency situations. this end, we propose leverage reasoning capabilities Large Language Models (LLMs) infer requirements from in-cabin...
Moisture infiltration significantly impacts the mechanical response of composite materials, thus diminishing their protective capabilities. To enhance performance materials under submersion and impact conditions, waterproofing treatments using a hydrophobic agent polyurea for were proposed fabricating total 10 types waterproof composites. The effects various on dynamic properties energy absorption characteristics rigid flexible composites before after exposure to salt spray aging...
Neonates with pneumonia (NWP) may experience unidentified life-threatening sepsis, yet distinguishing NWP from neonates sepsis (NWS) based solely on clinical presentation remains challenging. This study aimed to evaluate the diagnostic utility of C-reactive protein platelet ratio (CPR) in neonatal late-onset (LOS) among NWPs. From February 2016 March 2022, a total 1385 NWPs aged over 3 days were included. Of these, 174 confirmed positive blood cultures categorized into cohort, while...
Microbiota and its induced inflammation in colorectal mucosa have been considered risk factors for the development of carcinogenesis. Previous studies demonstrated that coexisting elements microbiota gut, such as short chain fatty acids (SCFAs) lipopolysaccharides (LPS), which exhibited regulatory effects on intestinal epithelial cells individually. Unfortunately, association between butyrate toll-like receptor (TLR) signaling pathway colon cancer is not fully elucidated. In present study,...
// Jun Li 1 , Shengke Yang 2 Junjie Hu 3 Hao Liu 4 Feng Du 5 Jie Yin 6 Sai 7 Ci 8 Shasha Xing 9 Jiatian Yuan Bo Lv Fan Shusheng Leng Xin Zhang and Bing Wang General Surgery Department, Affiliated Hospital/Clinical Medical College of Chengdu University, Chengdu, People’s Republic China Sichuan Cancer Hospital/Institution, Gastrointestinal Tumor Hubei Hospital, Wuhan, 2nd Hospital Jilin Changchun, Internal Medicine-Oncology, Institute/Hospital, Peking Union Chinese Academy Sciences,...
Exosomes derived from mesenchymal stem cells are of therapeutic interest because their important role in intracellular communication and biological regulation. On the basis previously studied nerve conduits, we designed a polydopamine-modified chitin conduit loaded with cell-derived exosomes that release sustained stable manner. In vitro experiments revealed rat enhanced Schwann cell proliferation secretion neurotrophic growth factors, increased expression Jun Sox2 genes, decreased Mbp...
Abstract Studies of quadruped animal motion help us to identify diseases, understand behavior and unravel the mechanics behind gaits in animals. The horse is likely best-studied this aspect, but data capture challenging time-consuming. Computer vision techniques improve extraction, development relies on reference datasets, which are scarce, not open-access often provide from only a few anatomical landmarks. Addressing gap, we introduce PFERD, video 3D marker dataset horses using full-body...
Objective To explore the clinical characteristics and treatment strategies of hip fracture triad (acetabular fracture, dislocation combined with proximal femur fracture). Methods A retrospective analysis was performed on 11 patients admitted to Shandong Provincial Hospital from January 2014 December 2020. There were 9 males 2 females; age (38.7 ± 12.2) years old (range 12–53 years). After all are hospital, a plan will be formulated based type associated injuries, long-term follow-up...
To establish machine learning(ML) models for the diagnosis of clinically significant prostate cancer (csPC) using multiparameter magnetic resonance imaging (mpMRI), texture analysis (TA), dynamic contrast-enhanced (DCE-MRI) quantitative and clinical parameters to evaluate stability these in internal temporal validation.The dataset 194 men was split into training (n = 135) validation 59) cohorts, a 58) used evaluation. The lesions with Gleason score ≥ 7 were defined as csPC. Logistic...
// Bo Lv 1, * , Xin Zhang Jun Li 2 Shusheng Leng 1 Shuqiang Yunlong Zeng Bing Wang Jiatian Yuan Fan Shasha Xing Ci 3 General Surgery Department, Affiliated Hospital/Clinical Medical College of Chengdu University, Chengdu, 610081, P.R. China Central Laboratory, Pathology These authors contributed equally to this work Correspondence to: Li, email: junl_paper@sina.com Keywords: absorbable clip, appendicitis, appendix stump closure, laparoscopic appendectomy Received: October 30, 2015 Accepted:...
// Jin Yang 1, * , Shasha Xing Jun Li 2, 3 Shengke 4 Junjie Hu 5 Hao Liu 6 Feng Du 7 Jie Yin 8 Sai 9 Ci 10 Jiatian Yuan 2 Bo Lv 1 Central Laboratory, Affiliated Hospital/Clinical Medical College of Chengdu University, Chengdu, China General Surgery Department, Department Surgery, Zhongshan Hospital, Fudan University Colorectal Cancer Research Center, Shanghai, Sichuan Gastrointestinal Tumor Hubei Wuhan, 2nd Hospital Jilin Changchun, Internal Medicine-Oncology, Institute, Peking Union and...
In this paper we present our preliminary work on model-based behavioral analysis of horse motion. Our approach is based the SMAL model, a 3D articulated statistical model animal shape. We define novel for horses new template, skeleton and shape space learned from $37$ toys. test accuracy hSMAL in reconstructing mocap data images. apply to problem lameness detection video, where fit images recover pose train an ST-GCN network data. A comparison with same trained points illustrates benefit approach.
Unit variance (UV) scaling, mean centering (CTR) and Pareto (Par) scaling are three commonly used algorithms in the preprocessing of metabolomics data. Based on our NMR-based studies, we found that clustering identification performances these methods were dramatically different as tested by spectra data 48 young athletes' urine samples, spleen tissue (from mice), serum cell Staphylococcus aureus) samples. Our suggested for extraction information, UV could serve a robust approach NMR analysis...
The aim of this study was to investigate the role miR-138 in osteoporosis and its underlying mechanism. Hydrogen peroxide (H2O2) used induce osteoporotic injury osteoblasts. cell viability apoptosis MC3T3-E1 cells assessed using MTT assay flow cytometry, respectively. transfection carried out modulate expression levels TIMP-1 cells. Luciferase reporter gene performed determine interaction between 3'UTR. In present study, H2O2 inhibited osteoblasts growth induced intracellular endoplasmic...
Neoadjuvant therapy (NT) for rectal cancer (RC) reduces primary tumors and involved lymph nodes. While a prognostic value of tumor regression grade (TRG) has been identified, node (LRG) not systematically evaluated. Here, we evaluated the association LRG with oncologic outcomes RC patients after NT followed by radical surgery. 347 locally advanced who received then underwent surgery were retrospectively recruited between 2004 2011. Response to was 3-tier TRG based on ratio residual fibrosis....
Resveratrol (Res), a naturally occurring polyphenolic compound, has been reported to exert many biological effects like anti-inflammatory and anti-oxidant effects.