A5057388317- Health Systems, Economic Evaluations, Quality of Life
- Clinical Nutrition and Gastroenterology
- Pharmaceutical Economics and Policy
- Nutrition and Health in Aging
- Economic and Financial Impacts of Cancer
- Asthma and respiratory diseases
- Electrolyte and hormonal disorders
- Abdominal Surgery and Complications
- Biosimilars and Bioanalytical Methods
- Cardiac, Anesthesia and Surgical Outcomes
- Atrial Fibrillation Management and Outcomes
- Cardiac Valve Diseases and Treatments
- Lung Cancer Treatments and Mutations
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Pharmaceutical studies and practices
- CAR-T cell therapy research
- Anesthesia and Sedative Agents
- Cancer Genomics and Diagnostics
- Inhalation and Respiratory Drug Delivery
- Antiplatelet Therapy and Cardiovascular Diseases
- Enhanced Recovery After Surgery
- Blood Pressure and Hypertension Studies
- Intensive Care Unit Cognitive Disorders
- Hemophilia Treatment and Research
- Chronic Lymphocytic Leukemia Research
Health Economics and Outcomes Research (United Kingdom)
2008-2024
Center for Outcomes Research and Clinical Epidemiology
2010-2024
Torino e-district
2005-2023
Ibero American University
2023
Respons
2015
Advanced Research Institute
2007-2008
University of Turin
2002-2004
Introduction To date, for all non-small cell lung cancer (NSCLC) cases, it is recommended to test driver alterations identify actionable therapeutic targets. In this light, comprehensive genomic profiling (CGP) with next generation sequencing (NGS) has progressively gained increasing importance in clinical practice. Here, the aim of assessing distribution and real-world frequency gene their correlation patient characteristics, we present outcomes obtained using FoundationOne (F1CDx)...
473 Background: The absence of validated prognostic and predictive biomarkers constitutes a significant barrier to appropriate selection among immune checkpoint inhibitor combinations (ICI-C) for individual patients (pts) with mccRCC. Our study aimed evaluate the value single-gene alterations (GAs) gene clusters in large real-world case series Methods: This employed data from US-based de-identified Flatiron Health-Foundation Medicine Inc. (FH-FMI) CGDB, comprising 858 mccRCC pts diagnosed...
BACKGROUND: The benefits of triple therapy for Chronic Obstructive Pulmonary Disease (COPD) have been established in two 52-week phase-3 randomized controlled trials. current systematic literature review (SLR) appraised available evidence on the real-world outcomes single-inhaler (SITT) when prescribed by general practitioners (GPs).METHODS: Using PICOS (Population, Intervention, Comparator, Study design) framework, a search was conducted to identify suitable studies review. PubMed and...
Previous studies and a meta-analysis in surgical patients indicate that supplementing parenteral nutrition regimens with n-3 polyunsaturated fatty acids (PUFAs), particular eicosapentaenoic acid (EPA) docosahexaenoic (DHA), is associated improved laboratory clinical outcomes the setting of hyper-inflammatory conditions. Refined or synthetic fish oils are commonly used as source EPA DHA. The objective present was to evaluate PUFA-enriched elective intensive care unit (ICU) patients. Medline...
Abstract: The aim of this document is to provide a set indications on the national best practice management knee osteoarthritis based an analysis existing literature and contribution experts in field. During first phase project, agreement with multidisciplinary panel experts, main guidelines topic were selected. Each guideline was assessed through AGREEII system identify their strong/weak points summary recommendations contained various documents drawn up. drew up list therapeutic options be...
Objective. Omalizumab is a biological treatment for difficult-to-treat allergic asthma. Its mechanism of action relies on impeding the binding immunoglobulin E (IgE) to specific cellular receptors, thus blocking inflammatory cascade. At present, no long-term data are available its cost/effectiveness. The aim this study assess clinical outcomes and measure cost/utility omalizumab use in asthmatics. Methods. clinical, economic, quality-of-life (QoL) 36-month add-on therapy were compared...
Disease-related malnutrition (DRM) is a prevalent condition that significantly increases the risk of adverse outcomes in hospitalized patients, particularly those with critical illness. Limited data available on economic burden DRM and cost-benefit nutrition therapy high-risk populations Latin America. The aims present study were to estimate evaluate supplemental parenteral (SPN) critically ill patients who fail receive adequate nutrient intake from enteral (EN) America.Country-specific cost...
Background & aimsThe Swiss supplemental parenteral nutrition (SPN) study demonstrated that optimised energy provision combining enteral (EN) and SPN reduces nosocomial infections in critically ill adults who fail to achieve targeted delivery with EN alone. To assess the economic impact of this strategy, we performed a cost-effectiveness analysis using data from study.MethodsMultivariable regression analyses were characterise relationships between SPN, cumulative deficit, infection, resource...
Hospital malnutrition is a highly prevalent condition that leads to an increased risk of clinical complications and corresponding increase in healthcare resource utilisation. Despite the high prevalence adverse consequences, limited data are available on magnitude economic burden associated with hospital Asian countries. The aim present analysis was calculate country-specific estimates Asia.Country-specific cost were used incremental costs attributable 11 countries Asia. cost-of-illness...
Background and study aims Artificial intelligence (AI)-assisted colonoscopy has proven to be effective compared with alone in an average-risk population. We aimed evaluate the cost-utility of GI GENIUS, first marketed real-time AI system Italian high-risk Methods A 1-year cycle cohort Markov model was developed simulate disease evolution a individuals positive on fecal immunochemical test (FIT), aged 50 years, undergoing or without system. Adenoma colorectal cancer (CRC) were identified...
Background: We aimed to estimate the economic and clinical impacts of a novel diagnostic test called LIAISON® MeMed BV® (LMMBV), which can differentiate bacterial from viral infections, in patients with community-acquired pneumonia (CAP) emergency departments. Methods: A cost-impact simulation model was developed investigate financial consequences introduction LMMBV into standard care (SOC) process Italy, Germany, Spain. Clinical outcomes were expressed as antibiotic days saved, reduced...